Indeed, clearly supporting the idea that NuA4/TIP60 does not use the same molecular mechanism as SRCAP to engage nucleosomes in order to incorporate H2A.Z. The multiplicity of histone mark reader modules in NuA4 likely playing a role.
Over the moon about my postdoc work @ScienceMagazine ! Ever wonder about how mammalian cells selectively degrade unwanted nuclear proteins without involving ubiquitination? Check out our paper on a non-canonical protein degradation mechanism! https://t.co/2geodpUuP5
Happy to see the preprint of the work I collaborated with during my postdoc at @EricGreerLab finally out! 🙌🏻 NOP16, a histone mimic protein that regulates H3K27me3 in breast cancer. https://t.co/IrkVpEVbdj
Thrilled to share that our paper is finally online @NeuroCellPress ! We address a paradox - how a short-lived #mRNA , Arc, can maintain long-lasting protein levels to execute its functions for #memory! A short thread...
https://t.co/Oxyv6tcDgk
Incredibly excited to share that I will be joining the #HHMINEWS family as a Freeman Hrabowski Scholar. This award will fund our work on neuroimmunological mechanisms of brain development and function over the next 5 - 10 years.
Are you interested in cell lineage tracing in a rapidly aging vertebrate? If so, you might want to check out a cool new preprint from @ItamarHarel lab: https://t.co/fxTZHYJz3h