Bringing a new perspective on material properties of biomolecular condensates by quantifying sequences dependent flow activation energies! A fantastic collaborative science with friends from @BanerjeeLab_UB
New research presents MELON-4D, a method for describing mesoscale organization of DNA within cell nuclei. Applied to the Drosophila nucleus, it shows how internal forces sculpt nuclear geometry in eukaryotes.
Read the paper: https://t.co/GqdjXj5XTl.
The first paper from a chem PhD student, Will Brown on phase separation of multicomponent peptide mixtures. Imagine cooking up a soup of peptides containing all 20 residues!!! How would the condensates turn out? Read on to find out😊 #hydration#LLPS
https://t.co/Gqn1jhcysG
Capping off a fantastic year with the group. And get this – this snapshot was taken right in the thick of winter, in the middle of December... in Iowa, no less! :D #grateful#globalwarming#ISU
We are on the cover of PLoS Comp Bio, Woohoo! 🥳🥳🥳 Thanks to the impeccable artistic and scientific skills of the Ph.D. student in our group Dan Burns. https://t.co/Pej2ApaJNu
Our foray into the dark world of low-complexity RNAs 🕵️♀️Using MD/ML, we try to make sense of the contributions of the polyphosphate backbone
vs. base to the heterogeneous conformational ensembles of Polynucleotides. Preprint by our talented second-year PhD student Vyskah.
Full nuclear alert!☢️A preprint by our incredible postdoc Dr. Rabia Laghmach on 4D modeling of eukaryotic nuclei (MELON-4D) 🍉. Rabia has pioneered mesoscale models resolving chromatin dynamics in full-nuclei. The paves the way for nuclear mechanobiology!
https://t.co/4u7fFkTHmC
Fresh preprint, just in time for #APSMarch. @RLaghmach is showing just how far a model of chromatin, based on a multiphase liquid condensate physics goes in predicting the nuclear organization and dynamics. #LLPS#Chromatin#Nucleus#MELON https://t.co/JKhZcx5gIU
If you want to learn more about our recent fascinating work on the 3D nuclear chromatin organization and dynamics, come check out my presentation at #APSMarch, on Thursday (tomorrow) at 12:06 PM CDT (Session S13 Physics of genome organization I). https://t.co/h2lgV8OUDv
We are excited to announce the official launch of the BIAPSS platform! https://t.co/34PGQ7CIkT A massive body of work done completely and independently by Dr. Aleksandra Badaczewska-Dawid. Hope the LLPS community will find it useful :) @Pha_Tran_Papers https://t.co/YBd1fJ9UNk
I am beyond thrilled and honored for receiving support from @RCSA1 What a fantastic opportunity to further our efforts in teaching and research. Excited to meet the fellow Cottrell Scholars 🤠