@StefanDiezLab@digsbb@BCUBE_TUDresden Congrats Rachele - well done! ๐๐ผ ๐๐ผHope you had a great time with your family - it was great fun to be with them!
Finally published-here we show opposite polarity motors bound to vesicular cargo are sufficient for directional reversals. Motors engage in a brief tug-of-war which is resolved by stochastic fluctuations in the number of engaged dynein and kinesin motors diffusing on cargo.
Our preprint is out in @NatureComms where we (with Santen Lab @Saar_Uni) show that vesicles transported by dynein and kinesin exhibit bidirectional motility (with reversals, pauses and fast runs) without any regulators. @digsbb@BCUBE_TUDresden@PoLDresden
https://t.co/HBn000NNbX
Listening to this while downloading some articles from Sci-hub. What an enormous contribution Alexandra Elbakyan! Hats off to you. I hope the Indian courts rules in your favor. Thanks for reporting this โฆ@Radiolabโฉ https://t.co/8ze7YiUfzO
To move or not to move: A novel in vitro assay successfully recreates intracellular bidirectional cargo transport.
๐ https://t.co/bfka60V1U1
@DivyaA_Pathak covers a #preprint from the @StefanDiezLab and Santen lab, led by Ashwin D'Souza (@ashwin47). Includes author comments ๐
@StefanDiezLab@Saar_Uni Long range motility of vesicular cargo propelled by opposite polarity motors, mimicking intercellular transport, reconstituted in a minimal system.
If you are interested to know how MAPs influence the vesicular transport. Do they favor Kinesin or Dynein please come visit my poster 92 #EESMicrotubules