WHO R&D Blueprint

Global action plan to prevent epidemics by accelerating R&D.
RTs ≠ endorsements #epidemicpreparedness #EIDs #publichealth #vaccines #diagnostics #medicines

[NEJM @NEJM]

In the phase 3 mRNA-1273 trial participants received 2 doses of vaccine or placebo 28 days apart. The mRNA-1273 vaccine showed 94.1% efficacy in preventing #SARSCoV2, including severe disease. #IDTwitter

[WHO R&D Blueprint @rd_blueprint]

@WHO thanks the nearly 1500 clinical researchers working in over 400 hospitals in 30 countries around the world for collecting this data in record time. Now for the next phase of the trial. @doctorsoumya @jarottingen @DrTedros

[Eric Topol @EricTopol]

Context for this important @WHO trial, beyond the results: 1300 participating doctors, >11,000 patients who got the answers so quickly 🙏
https://t.co/f1ZATWpg9P by @kakape w/ @JeremyFarrar @doctorsoumya
@virusninja @jarottingen @AnaMaraHenaoRe1 @BhadeliaMD @ScienceMagazine

[WHO R&D Blueprint @rd_blueprint]

@WHO congratulates @MTamfum, @inrb_kinshasa, @NIH
and WHO colleagues in the field for the critical trial with the @Regeneron monoclonal that is the first ever licensed treatment for Ebola virus disease https://t.co/CCYUhzIl0x

[Ghassan Karam @GhassanKaram]

Number of COVID-19 #clinicaltrials in the #ICTRP database https://t.co/pt4t96i23J @WHO @doctorsoumya

[Soumya Swaminathan @doctorsoumya]

The #Solidarity trial harnesses global cooperation in research to answer important public health questions related to #COVID19. @WHO @rd_blueprint created to undertake ethical research during emergencies @DrTedros @CPHO_Canada @jarottingen @JeremyFarrar @trevormundel @JEPaquetEU

[Helen Branswell 🇨🇦 @HelenBranswell]

It seems China's clinical trials may not have generated enough data to tell the world if repurposed drugs work against #Covid19. @WHO has launched a multi-arm, multi-country trial to fill this critical knowledge gap. https://t.co/uRR6WJlPYh

[Kai Kupferschmidt @kakape]

@WHO @DrTedros @DrMikeRyan @mvankerkhove Details on SOLIDARITY trial for #covid19 treatment: adaptive design, countries can choose, drugs can be added, but starting with 5 arms.
- standard of care
- remdesivir
- lopinavir and ritonavir
- lopinavir, ritonavir and interferon-beta
- chloroquine

[Kai Kupferschmidt @kakape]

@WHO @DrTedros SOLIDARITY trial provides simplified procedures so even overloaded hospitals can participate. Argentina, Bahrain, Canada, France, Iran, Norway, South Africa, Spain, Switzerland and Thailand already confirmed to participate.

[WHO R&D Blueprint @rd_blueprint]

There are now 508 COVID-19 trials listed on WHO ICTRP https://t.co/IOIhvueJmd

[Vasee Moorthy MD PhD @vaseemoorthy]

https://t.co/TVvvlL4T2w
4-pager distilling ethical guidance on COVID-19 research.
Great work from ethics group formed out of WHO R&D Blueprint COVID-19 research forum
@rd_blueprint @WHO

[Tedros Adhanom Ghebreyesus @DrTedros]

The potential spread of the #coronavirus to countries with weaker health systems is one of our biggest concerns. @WHO thanks @UNCERF for releasing $15 million to help these countries battle the spread of the virus. https://t.co/4VlGKHhfNd

[Tedros Adhanom Ghebreyesus @DrTedros]

Our message to all countries is: this is not one-way street. We can push this #coronavirus back.

Your actions now will determine the course of the #COVID19 outbreak in your country.

There’s no choice but to act now.

[WHO African Region @WHOAFRO]

An emotional day in #Beni #DRC as Masiko, the last #Ebola patient in DRC leaves the Ebola treatment centre in #Beni! Our @WHO team was delighted to share this victory with Masiko, @MinSanteRDC, our partners, & the people of Beni.

[Jeremy Farrar @JeremyFarrar]

#COVID19 issues. 3) Since SARS fundamental postive reforms in China and @WHO - the China Centre Disease Control professionalised, clinical care within China, Health Emergencies Programme @WHO, @DrTedros personal leadership, @DrMikeRyan @doctorsoumya @rd_blueprint & team

[World Health Organization (WHO) @WHO]

@DrTedros "The transition from #Ebola to universal health coverage provides a unique opportunity to strengthen the entire #DRC health system, as long as the political commitment translates into the adequate & progressive mobilization of domestic resources"-@DrTedros

[World Health Organization (WHO) @WHO]

Both Chinese & external expert groups are trying to identify the animal source of 2019-nCoV.
Identifying it would help to ensure that there will be no further similar outbreaks & will also help to understand the initial spread of #COVID19 in the Wuhan area, 🇨🇳

[World Health Organization (WHO) @WHO]

Daily press conference on #COVID19 with @DrMikeRyan. #coronavirus https://t.co/nJ2o3ilsTY

[Tedros Adhanom Ghebreyesus @DrTedros]

Look forward to joining President Felix Tshisekedi, @Presidence_RDC at the launch of #DRC 🇨🇩‘s National #UHC Strategy tomorrow.
In my absence, @DrMikeRyan briefed media on the #coronavirus response.

[Tedros Adhanom Ghebreyesus @DrTedros]

I'm really grateful to all the laboratory #healthworkers around the world, including those in 🇰🇭 in this photo, who are conducting #COVID19 tests with such great care. Their expertise & humanity are fundamental to stop #coronavirus from spreading further.

📷: @PasteurCambodia

[Tedros Adhanom Ghebreyesus @DrTedros]

We convened experts & R&D funders at @WHO to set priorities for stopping the #COVID19 outbreak, incl:
-how to apply diagnostics
-the best approaches for infection prevention
-potential therapies that could be used now
-existing vaccine candidates
-how to address the infodemic