Rohan Bhattacharya, Ph.D.

@BloodCancerUtd Fellow @Leonard_zon Lab Macrophage-MDS-AML @BostonChildrens @Harvardmed | Ph.D. @ProfSamiraMusah @DukeU CHD-AKI-CKD |Prev @novartis

[Rohan Bhattacharya, Ph.D. @rohanbme]

Thrilled to share that a part of my Ph.D. work from @DukeU @DukeCBTE @ProfSamiraMusah Lab is now out in @natBME!
We investigated the impact of CHD-linked SMAD2 variants on kidney development using engineered human iPS cells in a microphysiological system.

[Kyle.kimler @KimlerKyle]

1/8 The Human Gut Cell Atlas (HGCA) v1.0 is out on bioRxiv! https://t.co/VW1XOkr9SI
Built by the gut community, for the gut community. For this HCA resource, we aimed for high-resolution healthy cell subtypes and robustness for downstream tasks like label transfer.

[Rohan Bhattacharya, Ph.D. @rohanbme]

Thrilled to receive the CDP Fellow Award from @BloodCancerUtd to support my research on leukemia & macrophages! Grateful to my postdoc mentor @leonard_zon and collaborators for their guidance & support. Excited to advance this work & contribute to the fight against blood cancer.

[Rohan Bhattacharya, Ph.D. @rohanbme]

@yanirisma__ Congratulations!!!

[Katalin Susztak @KSusztak]

We updated our Susztaklabbiobank website https://t.co/IHMd3V0EW7
For almost two decades our laboratory has collected and profiled human kidney tissue, paired it with mouse and rat models and with the genetics of millions of people, and built one of the most complete maps of the human kidney that exists. This site is where we share it: genome-wide association results, expression, methylation, protein and open-chromatin maps, single-cell and single-nucleus atlases, spatial transcriptomes and animal-model resources, each in an interactive browser you can query today. Please send your suggestions how we could improve our site. Let's cure kidney disease together !

[Jennifer Trowbridge @TrowbridgeLab]

The Jackson Laboratory is a wonderful, collaborative place to pursue basic & translational science. On the faculty job market? I strongly encourage you to consider joining us in Bar Harbor, Maine!
Apply: https://t.co/blNIfvWMNG
#JAXresearch #JAXstemcellsdev

[Daniel Bauer @danielevanbauer]

Inspired by Gibson cloning, we describe prime assembly, now published, for in cellulo targeted integration of gene-sized DNA fragments using prime editing. https://t.co/XfNDIFkmzs

[Dr. Len Zon @leonard_zon]

Every so often, a major event happens in your life to validate years of work. SRRK’s ISEMBYLD was FDA approved. Having participated in its development from basic science to approval, as a physician-scientist, this is one of my best days. Happy for ISEMBYLD to help SMA patients.

[Rohan Bhattacharya, Ph.D. @rohanbme]

@leonard_zon Huge congratulations, Len!! @leonard_zon

[Rohan Bhattacharya, Ph.D. @rohanbme]

@annetkiraboc1 Congratulations, Annet!!

[Lara Wahlster @LWahlster]

We cut the ribbon & the Wahlster Lab is officially open! 🎉🔬

#NewPI #NewLab #PediatricCancer #CancerResearch #Hematology #HumanGenetics #Genomics #PhysicianScientist

🙏 to @bloodgenes @BostonChildrens @DanaFarber @BWFUND @ASH_hematology @DamonRunyon

[Rohan Bhattacharya, Ph.D. @rohanbme]

@KSusztak Wishing you a very Happy Birthday!! Have a wonderful weekend! :)

[Vijay Sankaran @bloodgenes]

🚨Two complementary preprints from our group reveal convergent mechanisms of inherited B-ALL predisposition. Check out this terrific work led by @LWahlster, @ALNeehus & #AndrewLee!
https://t.co/dUgwHcMyHo
https://t.co/M6keNjn1b0

[Karuna Ganesh @KarunaMDPhD]

Thrilled to share our latest work is out today in @Nature

ZFP36L2 orchestrates stress-adaptive plasticity in regeneration and cancer.

https://t.co/YFOTEapoB8

[Rohan Bhattacharya, Ph.D. @rohanbme]

@KSusztak @NatureGenet So cool! Huge congratulations to you and your team! :)

[Dr. Len Zon @leonard_zon]

We’re incredibly grateful to Legal Sea Foods for their continued support of my lab at Boston Children’s Hospital. This year, Matt King, Brand President & COO, presented a donation made possible through proceeds from kids' meals at Legal Sea Foods. Thank you for your support!

[Shiv Grewal @grewalsh]

Introns have a hidden regulatory role! 🧬🎉
Delighted to share our latest paper showing that inefficiently spliced introns and spliceosomal proteins direct RNA methylation, engaging RNAi to silence retrotransposons and regulate gene expression
https://t.co/tVTWTewauk

[Katalin Susztak @KSusztak]

😍🆕Great to see our APOL1 proteomics score (APRS) featured by @NatureGen . The work demonstrates how large-scale human proteomics can bridge the gap between genetic risk and clinical disease, bringing us closer to precision medicine for patients at risk of kidney failure. Congratulations to the entire team. @novartis @chenyu Penn Medicine Biobank https://t.co/QuUkB90EVC

[Michael Honigberg, MD, MPP @mchonig]

Delighted to contribute to this story now in @Nature led by T. Gerhardt & @cam_phd -

In humans & 🐭, exercise and 🛌 showed mutation-specific effects on clonal hematopoiesis, selectively reprogramming mutant cells toward less inflammatory states.

https://t.co/GmVkNSNdYP

[Katalin Susztak @KSusztak]

🤪🆕📰Our lab's newest paper ! KDM1A regulates nephron progenitor programs and is associated with human kidney disease risk https://t.co/A9Lbk4fnUE by @KLPrasu @DhanunjayMukhi Jonathan Levinsohn , Andi Bergerson , @Yan186186 @Hongbo919Liu @briancapell @Neph_Times @NDTsocial

[Katalin Susztak @KSusztak]

🗞️📸🌟🤩Beautiful work led by @BernhardDumoul1 with the team builds a single cell spatial atlas of human DKD using Xenium + CosMx + snRNA-seq. @Nature This is not incremental. This is a new layer of pathology. Diabetic kidney disease (DKD) is still treated as one disease. That is the problem. Patients look similar clinically but behave very differently. We asked: is there a biologically distinct subgroup we are missing?
https://t.co/Au83tayvR9