In this piece, my mentor Stu Orkin and I (1) marvel at prime editing—discovery to disease correction for 2 patients after just 6 yr—wow Liu, Anzalone, Gori, Malech et al! & (2) consider the challenges to deliver genetic medicine’s promise for 2^n patients https://t.co/ni2hs4btt9
1/6 🍍🍕🧬 What do a photo of Italians savoring pineapple pizza and a synthetic DNA sequence have in common? Both can be intricately crafted by generative AI! Introducing DNA-Diffusion, our AI model set to advance #SyntheticBiology and #GeneRegulation: https://t.co/rK4MzRnvw7
A wonderful read about Stu Orkin and @danielevanbauer and the road to Casgevy, a landmark for medicine and gene editing.
Collaborating with Dan and Stu was a highlight of my professional life and I personally will forever be in their debt for choosing to work with my team.
I'm thrilled to announce that our work, 'Epitope Editing Enables Targeted Immunotherapy of Acute Myeloid Leukemia,' is out today in Nature journal!
Link: https://t.co/nC05EjWMPw
doi: https://t.co/t8CWop6Z4k
In deepest grief, the Laboratory of Organic Chemistry at @ETH_DCHAB at @ETH_en announces that our friend and colleague, Prof. em. Albert Eschenmoser passed away peacefully, at the age of 97, on July 14, 2023.
Albert #Eschenmoser shaped organic chemistry as did few others. 1/3
I don’t usually post personal news but Clinicians have told us to pull every lever.
Our daughter has with #dipg Brain cancer. There is no cure and typically 9m life expectancy.
If anyone knows of trials then please get in contact! #braincancer#childrenscancer@CR_UK
Looking for postdocs for a couple of exciting projects on directed evolution and peptide catalysts. Come join our lab! https://t.co/FSTxvkl0a3 Please RT
"Unless things change dramatically, the millions of people #CRISPR could save will never benefit from it. We must, and we can, build a world with #CRISPR for all."
#healthjustice@igisci@nytimes
https://t.co/7VjfFdkLzJ
Please share! Our young team of biosynthetic designers @LeibnizHKI (Jena, D) is looking for a postdoc with experience in handling RNA. Thanks to the Boehringer Ingelheim Foundation for the Exploration Grant. More info in the job offer below & upon request.
https://t.co/3OXqJrKjIM
Die SVP verlangte heute an einer "ausserordentlichen Session" tatsächlich die Aufhebung der ausserordentlichen Lage gemäss Epidemiengesetz.
DIe Empfehlung des SVP-Sprechers Fredi Heer zur Bewältigung der #COVID-Pandemie? Sich beruhigen und Tee trinken.
#EinBildFuerDieGeschicht
It's Targeted Protein Degradation week! I had the pleasure to give an introduction to this exiting research area at the Prague-Weizmann Drug Discovery School @WeizmannScience today. The TPD summit @HansonWade starts tomorrow & the agenda is amazing! Many tweets will follow!
Keeping the ball rolling with my next manuscript from the @MartinJinek lab! We solved several
structures of intermediary binding states of Cas9 to elucidate the mechanism of target DNA binding and conformational activation!
https://t.co/DMrfLCCI0a
Good morning! The 70th Lindau Nobel Laureate Meeting starts today at 13.30 CEST with the Opening Ceremony. Find the full #LINO70 programme, the livestream, information on all participating Nobel Laureates and more on our website: https://t.co/wFapgujagP
Our latest https://t.co/HK2W5Fs10c, led by fantastic Divya Vinjamur, is out in Nature Genetics: We found a new HbF regulator (ZNF410) with wide therapeutic index and unique molecular mechanism. Bauerlab is recruiting new members https://t.co/UacI65Qe6G! 1/7