Samuel Mar

PhD cand. @NeuroOnco_USZ | System/#CancerNeuroscience | #BrainResearch 🧠🇪🇺 🇩🇪 🇨🇭 | Views are my own.

[Samuel Mar @Sam_Brains]

@JustinLathia I would have been honored to give you a tour in the city, enjoy your visit!

[Matthias Klumpp | @[email protected] @matxpp]

I am excited to announce our publication of "Syntalos" in @NatureComms: A software to easily and reliably record from multi-modal data sources and design closed-loop interventions, with a focus on (neuro)scientific experiments, all while keeping timestamps synchronized! 🧵1/9

[Samuel Mar @Sam_Brains]

@matxpp @NatureComms Big congratulations 🎉👏!

[Samuel Mar @Sam_Brains]

@to123w Amazing 🎉!

[Tobias W. @to123w]

Here a concise overview of our perspective on the role of functional precision medicine in the field of neuro-oncology
https://t.co/BshfsuyEDk

[Tobias W. @to123w]

Grateful for the opportunity to contribute to this fantastic article on leptomeningeal metastases, just published in Nature Reviews Clinical Oncology https://t.co/lZCuKuXRPp

[Neuro-Oncology_USZ @NeuroOnco_USZ]

Last week we had a wonderful time at our annual lab retreat with stimulating discussions! 🇨🇭

[Unispital_USZ @Unispital_USZ]

In einer Studie der @ETH Zürich und des USZ erwies sich ein bekanntes Antidepressivum als vielversprechende Lösung zur Behandlung aggressiver #Hirntumoren.
#Glioblastom
https://t.co/44NklAGrWV

[Samuel Mar @Sam_Brains]

https://t.co/Je881iC3GF

[Samuel Mar @Sam_Brains]

https://t.co/5WZa9LgS3c

[Samuel Mar @Sam_Brains]

https://t.co/hkjkBevfez

[Samuel Mar @Sam_Brains]

Check out our recent paper on #CNS drug discovery and biomarkers research in #Fragile_X-Syndrome mouse model🎉🧠🐀.
https://t.co/vgYyjOoFik

[Samuel Mar @Sam_Brains]

Check out our recent paper on auditory brainstem processing in Neurexin1α knockout rats, a model for neurodevelopmental disorders like schizophrenia and autism spectrum disorders. Published now @SciReports
https://t.co/okP52SSJCD

[Michael Okun @MichaelOkun]

Boom! Cerebrospinal fluid (CSF) flow extends to peripheral nerves. Alexander Ligocki, Ed Scott and colleagues @UF @UFHealth blow our minds. New paper @ScienceAdvances. What will we call it now? Cerebro-spinal-nerve fluid (CSNF)? or maybe brain-spinal-nerve fluid (BSN)? Just when you think you have a few ground truths of the brain and nervous system, you are humbled again.
Key Points:
- The authors point out that dogma holds that cerebrospinal fluid is responsible for 'maintaining brain homeostasis through nutrient delivery and waste removal for only the central nervous system.'
- They show extensive CSF flow throughout the peripheral nervous system.
- They traced multimodal 1.9-nanometer gold nanoparticles.
- These nanoparticles were roughly the size of CSF circulating proteins.
- They squirted them into the lateral cerebral ventricle.
-They showed incredibly that the particles transitioned from central to peripheral nervous systems at root attachments and transition zones.
- They showed the particles could make it all the way to the axoplasm of distal peripheral nerves.
- Bigger 15-nanometer gold particles were not able to make the journey.
My take: We know that the nervous system does not contain the more traditional lymphatics and has a force field called the blood brain barrier. We know that CSF delivers nutrients and removes waste from the brain and central nervous system. Our previous ground truth was established by studies using dye tracers. Using small gold nanoparticles these authors 'tore down the dogma.' So the real question is whether it is time for a name change? Cerebrospinal fluid (CSF) or cerebro-spinal-nerve fluid (CSNF)? or maybe brain-spinal-nerve fluid (BSN)? Thoughts? Sartor resartus – the tailor re-tailored our view on this important aspect of neuroscience. BRAVO!
https://t.co/63yeOGTaru #parkinson #CSF #cerebrospinal #Alzheimers

[Samuel Mar @Sam_Brains]

Check out our recent paper on using #ABRs combined with pharmacological tests in Sprague Dawley #WT and #Neurexin1α KO rats.
https://t.co/bBIcjjIt4t

[Samuel Mar @Sam_Brains]

@JulienHiblot @ScienceMagazine Very nice, congratulations to the whole team 🎉😁!

[EANO @EANOassociation]

#EANO2023 Congrats to Maximillian Mastall for being awarded with the Young Investigator Travel Scholarship! We look forward to meeting young scientists and physicians in #NeuroOncology. Registration is still open https://t.co/By6VxD2znl #btsm @max5tall @OncoAlert @theIBTA

[Samuel Mar @Sam_Brains]

Very inspiring talk from @VarunVenkatara2 !
A big honour to hear about the cutting-edge advancements in #CancerNeuroscience at 2023 ZNZ Symposium @ETH.

[Manuel Valiente @valientelab]

1/19 In our @Cancer_Cell paper we propose a novel mechanism by which brain mets could impact neuronal activity, independently of the mass effect.
https://t.co/KblvpEVOmT

[Earl K. Miller @MillerLabMIT]

New paper!
In vivo ephaptic coupling allows memory network formation
https://t.co/l19mN19xgJ

Neurons are like members of a huge orchestra. They need to coordinate to play a song. Ephaptic coupling spreads influences at the speed of light.
Work by @dimitrispp