Sam Levi

Med Chemist @Pfizer | Former PhD @chemical_phd @HarvardCCB

[Sam Levi @SamuelMLevi]

@Chemjobber @nytimes made the same mistake last year but never bothered to correct it!

[Zack Hauseman @ZHauseman]

What an amazing opportunity to be able to spearhead this project! Really enabled by the collaborative NIBR environment, a unique framework from the innovation postdoc fellowship, and top notch scientific mentorship.

[Sam Levi @SamuelMLevi]

Thanks so much @Dereklowe for highlighting our paper! I’m so lucky to be part of this fantastic collaboration. Can’t wait to see what @JacobsenLab has coming up!

[Sam Levi @SamuelMLevi]

The heart of the paper was inspired by the @KiesslingGroup’s AWESOME work on C-H pi interactions in glycan recognition, which drive the observed catalyst-controlled regioselectivity. I strongly recommend reading these papers immediately!
@ChemicalBiology

https://t.co/OfoZZwcHtP

[Sam Levi @SamuelMLevi]

The final chapter of my PhD has just been published @Nature! It was a true team effort getting this out with @AlisonWendlandt, Qiuhan, @CorinWagen, and @JacobsenLab. Thank you @NIH_CommonFund @NSF @HarvardCCB @chemical_phd for all your support! #glycotime

https://t.co/CsiBu7OFTC

[Sam Levi @SamuelMLevi]

@med_chemist But I’d rather make a glue…

[Sam Levi @SamuelMLevi]

@med_chemist When someone suggests we make a PROTAC

[Sam Levi @SamuelMLevi]

@med_chemist I love a good “Fact of the Day” on thermodynamics!

[Sam Levi @SamuelMLevi]

@KRHornberger I’ve been wondering what sorts of pharma/biotech positions are open to entry level PhD chemists that don’t require wet chemistry/lab based work?

I love my work in the Pfizer design role, but how common is it outside big pharma? (It’s a frequent question from new grads IMO)

[Sam Levi @SamuelMLevi]

@med_chemist Tecfidera. I’m not sure this exactly fits your definition since the “hit” was fumaric acid described as early as 1959 for MS, which was developed into the drug, dimethyl fumarate, and approved less than a decade ago.

https://t.co/2GmrdkUU7q

[The New York Times @nytimes]

Breaking News: Pfizer said its pill to treat Covid-19 had been found to be highly effective at preventing severe illness among at-risk people. It appears to be more effective than a similar offering from Merck, which is awaiting U.S. authorization. https://t.co/v89RrXaAKq

[Science Magazine @ScienceMagazine]

Researchers report the discovery of PF-07321332, an orally active, small-molecule inhibitor of the #SARSCoV2 main protease, a key viral target. In a phase I clinical trial, it achieved concentrations expected to inhibit the virus based on in vitro studies https://t.co/b3jLVzCNzE

[Sam Levi @SamuelMLevi]

@Dereklowe Thanks so much @Dereklowe for the write up!

[Sam Levi @SamuelMLevi]

From physical organic chemists to chemical biologists, we hope everyone finds elements of this outlook to enjoy! A big thank you to @ACSCenSci for hosting #openaccess

#PfizerChemistry #PFEColleague #MerckChemistry

[Sam Levi @SamuelMLevi]

Our new outlook in @ACSCentSci explores targeted protein degradation through a reactivity lens, shedding light on our growing understanding of ligand design and future opportunities in #TargetedProteinDegradation #TPD #chemicalbiology #chemistry

https://t.co/mlmJhKPM0t

[Sam Levi @SamuelMLevi]

I’m so happy to share our work on HPK1, a negative immune regulator, from my time at Merck. Congratulations @bran_chem and everyone involved!

#drugdiscovery #cancerresearch #Immunotherapy #immunooncology #MerckChemistry

https://t.co/tOBYNOawgn

[Science in the News @SITNBoston]

Chelsea Powell-postdoc at Harvard Medical School-discusses her experience transitioning into a new job right before the shutdown and shares important tips for incoming grad students.

Recorded: 5 November 2020
Featuring: Wei Li, Chelsea Powell

#scicomm

https://t.co/8Ccl8H3ghH

[Minnesota Department of Transportation @MnDOT]

The votes are in: After more than 122,000 votes cast, we’re excited to announce the winners of our Name a Snowplow contest! These eight names will soon be on snowplows across the state. Learn more: https://t.co/4BFXpnrtaz

[Steven Banik @StevenMBanik]

Check out this amazing video 1st year grad student @tineisadora (conceived, shot, edited and compiled the music!) put together to show off the chemistry and biology we do in the Banik Lab! Excited to have our first virtual visit @StanfordUChem, @Stanford_ChEMH, @CarolynBertozzi

[Sam Levi @SamuelMLevi]

Looking forward to hearing from this incredible group of speakers next week! #glycotime @KiesslingGroup @MillerGroupYale @NPohl_Group @MCGalan_Bristol @tang_weiping @JacobsenLab

[Alexei Demchenko, PhD, ACSF @glycoworld]

Please RT. #ACSCARB is a proud co-sponsor of this exciting #glycotime event organized by @glyco_pm @NPohl_Group @xiichen_XiChen Hien Nguyen and @glycoworld. Here is the link for more info and to register: https://t.co/YondbPyk6a Inviting @glyconet_nce @CarbGroupUK @CarboMet_EU