Sebastian Ols

Researcher in vaccine immunology, avid cyclist, and world traveller. Postdoc in the King lab @UWproteindesign. he/him

[Rodrigo Arcoverde Cerveira @CerveiraRodrigo]

It's finally out as a paper :D

🧵1/ Introducing scifer, our R/Bioconductor package developed with B cell receptor (BCR) sequences in mind, but adaptable to other sequence types. Pre-trained on real datasets, scifer is designed to streamline index cell sorting sequencing workflow

[The Nobel Prize @NobelPrize]

This year’s #NobelPrize laureates in chemistry have revealed proteins’ secrets through computing and artificial intelligence.

Chemists have long dreamed of fully understanding and mastering the chemical tools of life – proteins. This dream is now within reach. 2024 chemistry laureates Demis Hassabis and John M. Jumper have successfully utilised artificial intelligence to predict the structure of almost all known proteins. This year’s chemistry laureate David Baker has learned how to master life’s building blocks and create entirely new proteins. The potential of their discoveries is enormous.

The ability to create proteins that are loaded with new functions is just as astounding. This can lead to new nanomaterials, targeted pharmaceuticals, more rapid development of vaccines, minimal sensors and a greener chemical industry – to name just a few applications that are for the greatest benefit of humankind.

[The Nobel Prize @NobelPrize]

BREAKING NEWS
The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”

[Immunity @ImmunityCP]

We want to extend our warm congratulations to 2023 @NobelPrize Laureates Katalin Karikó and Drew Weissman! It was an honor to publish their key findings for the Physiology or Medicine prize: https://t.co/AqhPFAe5jG @kkariko @WeissmanLab @pennmedicine #NobelPrize

[Immunity @ImmunityCP]

One man's niche is another man's treasure 😀

[Sebastian Ols @sebbeols]

@GeoffreyHutch11 @CDzuvor @ImmunityCP Thanks Geoff!

[Sebastian Ols @sebbeols]

Happy to share our latest publication @ImmunityCP: Multivalent antigen display on nanoparticle immunogens increases B cell clonotype diversity and neutralization breadth to pneumoviruses
https://t.co/vQteifxPcT

[Sebastian Ols @sebbeols]

@ChrisSundling @Slack1Emma @ImmunityCP Tack Christopher!

[Sebastian Ols @sebbeols]

@DanLikeProteins @ImmunityCP Thanks Dan!

[Sebastian Ols @sebbeols]

@SmedSorensenLab @KingLabIPD Thank you Anna!

[Smed-Sörensen Lab @SmedSorensenLab]

Congratulations @sebbeols @KingLabIPD and not on x Karin Loré and colleagues! Great work! 🎉💪

[Immunity @ImmunityCP]

Online now: Multivalent antigen display on nanoparticle immunogens increases B cell clonotype diversity and neutralization breadth to pneumoviruses https://t.co/ql5CCpa2bL

[Sebastian Ols @sebbeols]

@Pradee05 @ImmunityCP Thank you Pradee!

[Sebastian Ols @sebbeols]

@karolinskainst @KingLabIPD @UWproteindesign @NIH @unil @BellinzonaIrb Expect a tweetorial thread to follow in the coming days!

[Sebastian Ols @sebbeols]

All in all, a fantastic collaboration with multiple researchers @karolinskainst @KingLabIPD @UWproteindesign @NIH @unil @BellinzonaIrb

[Jason McLellan @McLellan_Lab]

It's an incredible day for structure-based vaccine design, and I'm thrilled to see our prefusion RSV F antigen get approved as the first RSV vaccine. Still more work to do to reduce the RSV disease burden, but this will help! Congrats @BarneyGrahamMD! https://t.co/8L5JaNy49o

[Sebastian Ols @sebbeols]

@FarangiesG Danke schön 🫶

[Sebastian Ols @sebbeols]

Super happy and proud to share that I am one of the recipients of the KI Sven Gard Prize for the best virology doctoral thesis during 2022.
https://t.co/IW7Pf2MSn5

[Sebastian Ols @sebbeols]

@AviPadhi Thank you Avinash! :)

[Sebastian Ols @sebbeols]

@abarajitha96 Thanks Abi!