Now on bluesky: @cerveirarodrigo.bsky.social
Bioinformatics, vaccinology, immunology, science, art and cheese.
PhD student in Karolinska Institutet, Sweden
It's finally out as a paper :D
🧵1/ Introducing scifer, our R/Bioconductor package developed with B cell receptor (BCR) sequences in mind, but adaptable to other sequence types. Pre-trained on real datasets, scifer is designed to streamline index cell sorting sequencing workflow
A new research article was published in ImmunoInformatics
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Scifer: an R/Bioconductor package for large-scale integration of Sanger sequencing and flow cytometry data of index-sorted single cells https://t.co/Udc3AeaJB9
4/ Highly customizable and open-source, scifer is available on Bioconductor and GitHub. Fine-tune it for new applications, leverage parallel processing, and enjoy efficient, streamlined workflows. Contributions are welcome on GitHub issues! #OpenScience#Bioinformatics
What kind of childhood makes a top scientist? Is it enough to have all the right traits (brilliance, grit, etc) or do you need the right family too?
And why should we care? A 🧵 on our paper on the Nobel Laureates.
A teaser: the income distribution of the laureates' fathers.1/N
Modulation of innate immune response to mRNA vaccination after SARS-CoV-2 infection or sequential vaccination in humans: https://t.co/cm3pjY8xzk
@karolinskainst#Immunology#Vaccines
The chart shows the planetary boundaries. 6 of 9 have already been transgressed. Humanity has left the safe space (green) and entered high risk territory. https://t.co/nrXcHxIp9g
Dengue outbreaks can affect 390 million persons yearly. In a trial involving 16,235 persons in Brazil, the live, attenuated, tetravalent Butantan vaccine was efficacious in all age groups at 2 years. Read the full trial results: https://t.co/YY0iRP2Xqb
A dense system of pre-Hispanic urban centers, characterized by constructed platforms and plazas and connected by large, straight roads, has been discovered in the upper Amazon.
Learn more in the latest issue of Science: https://t.co/TrQ3NDDLnc
"The next moonshot in life sciences is decoding the human immune system."
Learn why modeling the immune system can transform global health, and how we plan to do it, in this must read from @janemetcalfe in @TheAtlantic: https://t.co/qwgrHY42VJ
BREAKING NEWS
The 2023 #NobelPrize in Physiology or Medicine has been awarded to Katalin Karikó and Drew Weissman for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19.
Happy to share our latest publication @ImmunityCP: Multivalent antigen display on nanoparticle immunogens increases B cell clonotype diversity and neutralization breadth to pneumoviruses
https://t.co/vQteifxPcT
Bora Guloglu's article on how VL domain identity can influence CDRH3 structure and dynamics has just been published in @FrontImmunol!
https://t.co/rBLr7WtFRT
10/10 This was collaborative work with the help of many collaborators. Including @CureVacRNA, @Loeffler_News , @NillaKH. This study was conducted in Karin Loré group, at @karolinskainst , by Fredrika Hellgren, @doc_brown79 , and myself.
1/10 Have you ever thought about comparing the immune response of a new mRNA vaccine platform with a traditional inactivated vaccine? We have done that for a #rabies vaccine and evaluated in detail its elicited immune responses.
https://t.co/5jsl92tcD6