@DanGrahamMD Looks biphasic with a glandular component and a small round cell tumor component. The glandular component could be examined with pancyto, CK7, TTF1, and CDX2 to start with. The small round blue cell tumor could be examined with pancyto, CD45, CD99, desmin, and myogenin first.
An unusual case - a rectal somatostatin-positive neuroendocrine tumor. Note the psammomatous calcification (arrow), a characteristic feature of somatostatinomas, like their proclivity to form tubules to mimic adenocarcinoma, all described years ago. PMID: 6139028 #UMiamiPath
Hi friends!
Anyone up for a long overdue #NatPathPuzzler 🔬🧩?
Well… ready or not, here it comes.
Lung nodule in a patient with history for breast carcinoma.
Are you team H&E or team IHC - is IHC needed here?
#PulmPath@PulmPathSoc@MSKPathology
It's out! We report 3D mapping of human pancreatic precancer and associated genetic alterations. With the brilliant @AshleyKiemen and @deniswirtz . Tweetorial to follow soon. https://t.co/fTYX77MM6v
Hello #GIpath friends!
What criteria do you use for dx of GI GVHD? Poll below
Here's a nice example of gastric involvement by GVHD.
Differentials include;
1. Infections - CMV, adenovirus, cryptosporidium
2. Medications - MMF, NSAIDS, PPIs, 5-FU etc
3. Sadly, bowel prep
Bladder tumor from a 56 year old man. Your diagnosis?
- PUNLMP or Ta Low-grade Urothelial Carcinoma?
- Does it make a treatment difference?
#gupath#pathology