jason

[Dalton (Analyze & Optimize) @Outdoctrination]

Vitamin E megadosing nearly doubled testosterone in response to stimulation in clinical trial.

483 mg for 8 weeks rose baseline T by >100 points.

T rose from 415.5 → 609.2 ng/dl (↑1.47x) after hCG stimulation.

But with vitamin E? 552.7 → 1015.7 (↑1.85x)

hCG is a hormone that stimulates the testes to produce T.

If you've been eating seed oils most of your life - your tissues are likely starved for vitamin E, and this impairs cell signaling and structure at nearly every level.

[Camus @newstart_2024]

Want to clear your sinuses and calm your nervous system for free? Just hum.

James Nestor says humming boosts nitric oxide in your nasal passages by up to 15x, helping with rhinitis and sinus issues. One guy reportedly cleared his rhinitis by humming 10 minutes, 4 times a day. It also stimulates the vagus nerve for instant calm.

Pick a song you like and hum along.

What’s your take, have you tried humming for better breathing or calm?

[Dan Go @CoachDanGo]

The biggest cheat code is sweating every day. It boosts blood flow, accelerates collagen turnover, flushes toxins through your pores, and triggers heat shock proteins, which are great for skin elasticity and anti-aging. Daily sweating is the cheapest health routine on earth.

[Startup Archive @StartupArchive_]

Peter Thiel’s advice to his younger self: “Value substance over status”

“One of the resolutions I came up with a number of years ago was to always value substance over status… I think if I’m honest about it, too much of [what I did] was driven by prestige and status—and not quite enough by the substance of really trying to learn things.”

Thiel continues on to explain that seven months into working at a prestigious law firm after graduating from Stanford Law School, he had a “quarter-life crisis” and quit.

“All you had to do was go through the front door, but peoples’ identities get so wrapped up in the things they compete for that it was inconceivable for people to actually do that.”

When he reflects on how he ended up in this situation, Thiel says:

“I think I had taken too many of these shortcuts of valuing what was prestigious and conventional over what I really wanted to do.”

Source: @StanfordLaw (Oct 2014)

[Investment Wisdom @InvestingCanons]

“If you are not aggressive, you are not going to make money, and if you are not defensive, you are not going to keep money.”

— Ray Dalio

[Vance 🌞⚡️ @VanceE]

My bad, let me speak plainly.

If you have depression or anxiety and are spending thousands on talk therapy and not $50 on probiotics, you might not make it.

But it’s bad depression?

“L. rhamnosus may have a more pronounced effect on individuals with more severe depressive symptoms”

How long?

“Moludi et al. found a 12-week L. rhamnosus supplement significantly reduced moderate to severe depression cases from six to zero”

I am blown the fk away again.

[Ada YU @AdaYU007]

抗衰科学家 David Sinclair 推荐大家多喝抹茶！

他解释：抹茶在生长后期会遮荫处理，因缺少阳光，茶树会大量分泌叶绿素，从而使多酚含量极高，抗氧化能力远超普通绿茶，口感也更好。

他本人已放弃咖啡，长期改喝抹茶。

[Huberman Lab Clips @HLPClips]

How to reduce nighttime urination:

"Daily fluid target is 8 oz (240 ml) per hour for the first 10 hours after waking."

"Gulping fluid moves it through your system faster than sipping due to mechanosensors in the gut; in the evening, sip rather than gulp to slow excretion."

"Limit intake to 5-8 oz between the 10-hour post-waking mark and bedtime, assuming adequate daytime hydration."

"Waking once or twice per night to urinate is normal; following this protocol can reduce that number to zero for most people."

@hubermanlab

[George Ferman @Helios_Movement]

Here's how repressed emotions can make you sick and what to do about it.

Thread🧵

[theendeavorpath @theendeavorpath]

“The biggest mistake you can make is waiting for the perfect moment.”

— Dana White

[Brandon Luu, MD @BrandonLuuMD]

In a new study of mice, the brain moved with abdominal muscle contractions, not breathing or heartbeat.

The belly is mechanically linked to the brain.

[宇峒 @xYsfknBXPT6M0jo]

泡菜被证明能真正增强免疫系统，在提升天然防御能力的同时防止炎症过度反应。

一项具有里程碑意义的人体试验表明，将泡菜纳入饮食可在短短12周内改变免疫细胞的活性，帮助身体增强防御能力，同时避免不必要的有害炎症。

这项随机、双盲研究评估了超重成人，他们摄入的是安慰剂、由天然发酵泡菜制成的泡菜粉，还是使用特殊发酵剂培养的泡菜。通过利用尖端的单细胞RNA测序技术追踪单个细胞内的基因活性，研究人员发现，摄入泡菜直接针对我们生物学的两个关键组成部分：呈递抗原的细胞（它们识别病原体并警示身体）以及CD4+ T细胞（它们协调整体免疫防御）。

至关重要的是，该研究显示泡菜作为一种“免疫调节剂”，这意味着它有助于精细调节免疫系统，使其保持完美平衡，而不是盲目增强它。这种双重作用激活防御途径，同时抑制不必要的、过度反应的信号，这些信号可能引发慢性炎症。虽然两种类型的泡菜都支持这种免疫平衡，但使用发酵剂培养的泡菜在增强病原体识别途径方面表现出更显著的效果。尽管该研究规模较小，且泡菜并非万能药，但这些发现提供了强有力的临床证据，说明传统发酵食品如何从肠道向外影响我们的生物学。

[Ada YU @AdaYU007]

两性专家 Alison Armstrong 说：女人最不理解男人的，就是他的荣誉感。

当一个男人意识到自己无法给深爱的女人所需的东西时，无论多爱她，都会选择离开——因为留下来是不光彩的。

而大多数女人根本不知道男人是这样想的。

作为女性，我看完真的很震惊！ 😅

[David Senra @davidsenra]

“Failure is so much more interesting than success.

And it always saddens me that school doesn't teach that.

At school the thing is to be brilliant and to get the answer right first time. And there are brilliant people who could do that, but for the rest of us who are not brilliant, we have to strive, and we have to go through failure.

And we realize that you don't get it right the first time or the second time. In my case and I counted it. It took 5,127 times.

With failure you question it “Well why did it go wrong?” And actually the reason it goes wrong is often very, very interesting.

Where something works you say “Great that worked.” You don't even stop to wonder why it works.

So if you've got to enjoy failure.”

—James Dyson

[Dan Go @CoachDanGo]

An 80-year-old who lifts weights can be as strong as a 30-year-old who doesn't.

[Camus @newstart_2024]

Medieval teachers used to throw kids in rivers after lessons, to create a big emotional spike so they’d actually remember what they learned.

Andrew Huberman says the same principle works today: If you want to lock in new information, get your adrenaline up right after studying or reading.

A double espresso, ice bath, or anything that gets your heart racing immediately after learning helps tag the info as important and store it better.

Post-learning adrenaline release enhances memory consolidation. Studies by James McGaugh and others show that elevating catecholamines (e.g., via exercise, cold exposure, or caffeine) shortly after learning significantly improves long-term retention by strengthening synaptic connections in the brain.

[jason @sowhatn]

@anblk984 后面的人有可能嘲讽了。可能再加上本来对这个男生没有好感。

[Dalton (Analyze & Optimize) @Outdoctrination]

Breathing slowly increased risk taking, and made those decisions feel more rewarding, in this study.

This is thought to be mediated by the parasympathetic nervous system.

Breathing slow ⇨ increased parasympathetic tone ⇨ more relaxation ⇨ more risk taking.

Higher sympathetic tone ⇨ greater activity in select brain regions ⇨ more reward / dopamine signaling.

[Mars Men @mengotomars]

HOW TO MAXIMIZE T3 (the beauty hormone):

• Iodine – seafood, dairy
• Selenium – Brazil nuts, sardines
• Beef liver (rich in copper and nutrients)
• Vitamin B6 (milk, meat, and organ meats)
• Calcium-rich foods (cheese, raw milk, figs)
• 400IU Vitamin E (very effective at lowering prolactin)

If you want to improve your aesthetics FAST, increase your T3

[Ada YU @AdaYU007]

美国著名科学家 Dr. William Li 每天服用罗伊乳杆菌（Lactobacillus reuteri） 来预防蛀牙！

这种益生菌不仅能改善肠道健康、提升免疫力、降低炎症，更特别的是，它还能直接杀死导致蛀牙和牙龈疾病的有害细菌。

所以他选择咀嚼型补充剂，连续10年没有长过蛀牙！