Jane Stinchcombe

Cell biologist/electron microscopist, delighting in the beauty and function of immune cells

[Mike Morgan @MDMorgan_abz]

@AlexanderDent6 These three had to be the stand out papers in immunology for me, barely a single cell in sight: https://t.co/SUO3oPzboK
https://t.co/ANS2W6ZG4N
https://t.co/xFDVDXZYob

[King's College, Cambridge @Kings_College]

On #WorldCancerDay we celebrate the researchers at Cambridge and across the world laying the foundations for improved cancer therapies.

Like Professor Gillian Griffiths (KC 1980, and Fellow) and all at the @griffiths_lab

💻https://t.co/n4V1GQP9rP
📰https://t.co/5I7O9REbAm

[The Royal Society @royalsociety]

Have you checked out the full programme for the #SummerScience exhibtion 2023? With talks, activities, Lates and over three hundred scientists talking about their research, find out more about this celebration of exciting research: https://t.co/ql3DfSelCn

[The CIMR @TheCIMR]

New @LabWeekes @TheCIMR research identifies cell surface markers of severe #COVID-19
https://t.co/7IMxVBvLxZ

[Nature Rev Immunol @NatRevImmunol]

NEW Highlight of @ScienceMagazine paper by @StinchcombeJane @griffiths_lab showing that TCR+ ectosomes (green) bud from the surface of a cytotoxic T cell (red) at the immune synapse, which terminates TCR signalling and promotes dissociation from target
https://t.co/1nL6KkaCh6

[Lasker Foundation @LaskerFDN]

A new study reveals that cytotoxic T lymphocytes (CTLs) shed activated T cell receptors through ectocytosis, not endocytosis as previously thought. This helps explain how CTLs are able to rapidly destroy multiple target cells in succession. @griffiths_lab
https://t.co/rtNmJeb5rI

[Stella Hurtley @SMHSci]

Ectocytosis renders T cell receptor signaling self-limiting at the immune synapse https://t.co/JXchfFbKuN

[Jane Stinchcombe @StinchcombeJane]

@AnhHLe2702 @AdamRochussen @griffiths_lab @ScienceMagazine @TheCIMR Great questions. Things to further look into.

[Jane Stinchcombe @StinchcombeJane]

Delighted to share our latest research following T cell receptor (TCR) by 3D TEM and showing ectocytosis makes TCR signalling self limiting at the immune synapse.

Many thanks to everyone involved.
@griffiths_lab https://t.co/5kNV1Sf9OW

[TwistedDoodles @twisteddoodles]

Halloween costumes to scare scientists (cartoon for @newscientist ) #halloween #AcademicTwitter

[Cambridge University @Cambridge_Uni]

Is the killer T cell the #JohnWick of the immune system?

Cytotoxic T cells are trained assassins who can kill and kill again. Scientists at @griffiths_lab @TheCIMR have captured them on film hunting down and destroying #cancer cells: https://t.co/51BS8eClXs

@wellcometrust

[Seth Thomas Scanlon @ImmunoEditor]

This week in @ScienceMagazine: @miriamlisci, @griffiths_lab, & colleagues at @TheCIMR, @MRC_MBU, & @dundeeuni
report that mitochondrial translation regulates serial killing by cytotoxic T cells!

https://t.co/4A565s0tcW

#CTLs #mitochondria

[Julian Rayner @rayner_julian]

Such a significant day for #malaria It’s not a perfect vaccine, it’s not the end of the road, but it’s a huge step forward that will save lives. Massive effort by so many people to reach this point. 🎉💯

[nature @Nature]

Sign up for Nature Briefing for the chance to win a 500-piece puzzle that celebrates fifteen groundbreaking female scientists. https://t.co/EpFoW2RIAp

[Tiphaine Douanne @TiphaineDouanne]

What do the primary cilium and immune synapse have in common (except for being two of my favourite things)? Read about it in our perspective for @JCellBiol @griffiths_lab @StinchcombeJane #cilia #immunesynapse #Tcells.

[Journal of Cell Biology @JCellBiol]

In a new perspective, @tiphainedouanne, @stinchcombejane and @griffiths_lab discuss #cilia and immune #synapses, two distinct biological structures that share common molecular mechanisms https://t.co/G8Edm3Whtb

#Immunology #Trafficking

[Rare Disease Day @rarediseaseday]

Today is #RareDiseaseDay!

There are over 6⃣0⃣0⃣0⃣ rare diseases

🌏 300 million people live with a rare disease accross the world

Rare diseases currently affect 3.5% - 5.9% of the worldwide population👨‍👩‍👧‍👦

Learn more about what is a #raredisease

👉https://t.co/4axpDU3ofy

[Rare Disease Day @rarediseaseday]

📢 NEW! The official #RareDiseaseDay video is out NOW

🎉Watch the 6 real life stories and be inspired to join the 2021 campaign.

👥 Share this post with your followers using this hashtag #RareDiseaseDay

[Nature Portfolio @NaturePortfolio]

World View: “If the rich world continues to hoard vaccines, the global pandemic will drag on for perhaps as long as seven more years,” writes @GYamey. https://t.co/tdGPd6VJdg

[Cambridge Immunology Network @Cambridgeimmuno]

Congratulations to Colucci and Sharkey groups for their article being featured in Nature Communications Editors’ Highlights “Immunology”! @DrFran_Colucci @Cam_Repro @NatureComms https://t.co/Of87Bulz3A https://t.co/BIQzylmgwO