It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). I’m reaching out to identify clinicians/patients who have encountered pediatric IDCS, indeterminate dendritic cell histiocytosis or other (non-LCH) histiocytic sarcomas cases.
I'm trying to understand non-surgical chemo and targeted therapy options, new pathology markers to better diagnose subtypes/treatments, and any data on progression in pediatric patients. Please feel free to share – I’m trying to cast a wide net due to the rarity of this condition and how little is known.
People can contact me directly at my first name (as written in my profile) at https://t.co/ubo0zQRMn0.
New paper with @theMaxwellLab :
Phage reprogramming of Pseudomonas aeruginosa amino acid metabolism drives efficient phage replication
https://t.co/XBDPHTpe6K
If you submit your grants last minute, you're in good company. Half of the applications were submitted in the last two days, in the 2005 NIH Pioneer grant cycle. The red bars indicate the awardees; one of them submitted just 8 minutes before the deadline.
🚨New preprint from our lab! We map the RNA interactions in E. coli infected by lambda, revealing an RNA-driven regulatory layer in phage-host dynamics. We find a phage-encoded sRNA hijacking host replication machinery, impacting the phage cycle.#microbiology#phages@MeetingRna
We’re here at @WCHospital for the #GairdnerScienceWeek Women of Gairdner Event!
High school students, researchers and local faculty are here with 2024 Canada Gairdner Award laureates Drs. Meghan Azad, Gagandeep Kang, and 2022 #GairdnerAwards winner Dr. Deborah Cook
Watch the webinar now! https://t.co/7ZUNL5EyFD
Please RT. 1x postdoc and 1xPhD position available in our group to study the role of NLR-like proteins in cellular development and antibiotic production in Streptomyces.
Postdoc: https://t.co/1dxVBIizvm
PhD position: https://t.co/W8DjdW3Brd
Email me for more information.
This was a wonderful meeting @SPP2330 again! Great kick-off of our second funding period!
Amazing science going on in the phage field and great to see students/postdocs from the first funding period starting their independent labs.
@dfg_public, @fz_juelich, @HHU_de
We are ready to go for the Annual SPP2330 Meeting on “New Concepts in Prokaryotic Virus-host Interactions”! With a fantastic line up of speakers: Alexander Harms @AHarms485, Karen Maxwell @theMaxwellLab, Samuel Kilcher @SamuelKilcher, and Mathias Middelboe @mmiddelboe1
Rare opportunity to join my team, as the @PLOSBiology in-house editorial team is growing!
It's a great team in a great journal, if I say so myself 😆
Please reach out if your have Qs & apply if interested!!
UK or US; assoc or senior
Please RT
https://t.co/hzAuin4pRS
Congratulations to @UofT_dlsph postdoc fellow @michelle_olding on receiving the 2024 EPIC Career Transition Award to lead an independent project looking at the role of prescribed safer supply programs in improving access to HIV and HCV care!
Read more: https://t.co/O0aqTCOyH3
This is definitely one of the longest running projects in the lab b/c we were stuck in a trap of thinking about Sie proteins blocking competing phages. But wasn't a satisfying answer to fit the biology we observed - kudos to @vee_coli for persevering and figuring it out!
New prepint alert @themaxwelllab! 📢 📢 📢 Superinfection exclusion (Sie) proteins aren’t just for defence – they also ensure the spread of viral progeny! Prophages that lack Sie proteins devour their young via a process we call the Kronos effect.
https://t.co/uxv42rYPoJ