Karen Maxwell

Phage biologist focused on virus-host interactions and bacterial pathogenesis.

[Sri Kosuri @srikosuri]

It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). I’m reaching out to identify clinicians/patients who have encountered pediatric IDCS, indeterminate dendritic cell histiocytosis or other (non-LCH) histiocytic sarcomas cases.

I'm trying to understand non-surgical chemo and targeted therapy options, new pathology markers to better diagnose subtypes/treatments, and any data on progression in pediatric patients. Please feel free to share – I’m trying to cast a wide net due to the rarity of this condition and how little is known.

People can contact me directly at my first name (as written in my profile) at https://t.co/ubo0zQRMn0.

[Patrick R. Secor @PRSecor]

New paper with @theMaxwellLab :

Phage reprogramming of Pseudomonas aeruginosa amino acid metabolism drives efficient phage replication
https://t.co/XBDPHTpe6K

[Karen Maxwell @theMaxwellLab]

Amazing work by @LandonGetz and team!

[Karen Maxwell @theMaxwellLab]

@JoeBMcPhee I agree. What kind of animal does that?

[Karen Maxwell @theMaxwellLab]

There are people that submit their grants more than 8 minutes ahead of the deadline???

[Itai Yanai @ItaiYanai]

If you submit your grants last minute, you're in good company. Half of the applications were submitted in the last two days, in the 2005 NIH Pioneer grant cycle. The red bars indicate the awardees; one of them submitted just 8 minutes before the deadline.

[Sahar Melamed @SaharMelamed]

🚨New preprint from our lab! We map the RNA interactions in E. coli infected by lambda, revealing an RNA-driven regulatory layer in phage-host dynamics. We find a phage-encoded sRNA hijacking host replication machinery, impacting the phage cycle.#microbiology #phages @MeetingRna

[Gairdner Foundation @GairdnerAwards]

We’re here at @WCHospital for the #GairdnerScienceWeek Women of Gairdner Event!

High school students, researchers and local faculty are here with 2024 Canada Gairdner Award laureates Drs. Meghan Azad, Gagandeep Kang, and 2022 #GairdnerAwards winner Dr. Deborah Cook

Watch the webinar now! https://t.co/7ZUNL5EyFD

[Susan Schlimpert @SusanSchlimpert]

Please RT. 1x postdoc and 1xPhD position available in our group to study the role of NLR-like proteins in cellular development and antibiotic production in Streptomyces.

Postdoc: https://t.co/1dxVBIizvm
PhD position: https://t.co/W8DjdW3Brd

Email me for more information.

[FrunzkeLab @FrunzkeLab]

This was a wonderful meeting @SPP2330 again! Great kick-off of our second funding period!
Amazing science going on in the phage field and great to see students/postdocs from the first funding period starting their independent labs.

@dfg_public, @fz_juelich, @HHU_de

[New Concepts in Prokaryotic Virus-Host Interaction @SPP2330]

Julia Frunzke @FrunzkeLab opening the annual @SPP2330 meeting! Looking forward to 3 exciting days of science! @dfg_public

[New Concepts in Prokaryotic Virus-Host Interaction @SPP2330]

We are ready to go for the Annual SPP2330 Meeting on “New Concepts in Prokaryotic Virus-host Interactions”! With a fantastic line up of speakers: Alexander Harms @AHarms485, Karen Maxwell @theMaxwellLab, Samuel Kilcher @SamuelKilcher, and Mathias Middelboe @mmiddelboe1

[Karen Maxwell @theMaxwellLab]

@PRSecor @MSU_MicroImmuno @montanastate Wow! Congratulations Pat!!!!

[Karen Maxwell @theMaxwellLab]

@Bruce_G_Allen MID panel success rate was only 13.3% (8 of 60). I suspect that the 15.3% rate may be bolstered by one year bridge grants.

[Nonia Pariente @npariente]

Rare opportunity to join my team, as the @PLOSBiology in-house editorial team is growing!
It's a great team in a great journal, if I say so myself 😆
Please reach out if your have Qs & apply if interested!!
UK or US; assoc or senior
Please RT
https://t.co/hzAuin4pRS

[PhD_Genie @PhD_Genie]

A supervisor, postdoc and the new PhD candidate

https://t.co/xUXtWJiI4M

[Karen Maxwell @theMaxwellLab]

@liyuping927 @biozentrum @NCCR_AntiResist @UniBasel_en @ElginKorkmazhan Congratulations! Looking forward to seeing some cool work coming out of your new lab!!

[U of T Emerging and Pandemic Infections Consortium @UofTEPIC]

Congratulations to @UofT_dlsph postdoc fellow @michelle_olding on receiving the 2024 EPIC Career Transition Award to lead an independent project looking at the role of prescribed safer supply programs in improving access to HIV and HCV care!

Read more: https://t.co/O0aqTCOyH3

[Karen Maxwell @theMaxwellLab]

@MarraffiniLab @AKShilton Congratulations again Amanda - you did a wonderful job! Thanks again for inviting me to be part of your big day!!!

[Nature Communications @NatureComms]

Anti-phage defence through inhibition of virion assembly

@theMaxwellLab @pramalpatel

#phages #antiphage #prophages #phagedefence

#bacteria #microbiology #virology

https://t.co/GmDTGXTBKA

[Karen Maxwell @theMaxwellLab]

This is definitely one of the longest running projects in the lab b/c we were stuck in a trap of thinking about Sie proteins blocking competing phages. But wasn't a satisfying answer to fit the biology we observed - kudos to @vee_coli for persevering and figuring it out!

[Véronique Taylor @vee_coli]

New prepint alert @themaxwelllab! 📢 📢 📢 Superinfection exclusion (Sie) proteins aren’t just for defence – they also ensure the spread of viral progeny! Prophages that lack Sie proteins devour their young via a process we call the Kronos effect.
https://t.co/uxv42rYPoJ