Ujjwal

Understanding fetal tolerance @cincychildrens

[Sing Sing Way @babiesresearch]

@Model.ShareSubject https://t.co/ShRyVwk6z4 Our pilot data giving women at high risk for pregnancy complications free mouthwash shows some amazing protective effects! Thank you @MarchofDimes @ProcterGamble @BraxtonForde @CincyResearch @UCincyMedicine

[Ujjwal @ujjwaladh1]

If reproductive fitness is prioritized, then pregnancy isn’t just a reproductive state. It may be that window into how the immune system evolved.
#pregnancyimmunology

[Sing Sing Way @babiesresearch]

Learning immunology from mothers and babies https://t.co/Dwz3HepTGL The maternal-fetal dyad can reveal new approaches for improving pregnancy outcomes, but also how the immunology works applicable to many other physiological contexts @MucosalImmunol @socmucimm @Lukeocyte_bio

[Sing Sing Way @babiesresearch]

Candidalysin promotes fungal-specific Th17 CD4 T cell differentiation and protective systemic immunogenicity - Mucosal Immunology https://t.co/ct37O7ROav part of the lab investigates commensal fungi as another example of expanded tolerance, but have instead found immunogenicity

[Sing Sing Way @babiesresearch]

Mama's T cells need KLF2 for promoting fertility and optimal pregnancy outcomes. Great work by @Abrady81 @Lukeocyte_bio and the entire lab
Maternal Krüppel-like factor 2 (KLF2)+ CD4 T cells promote fertility and fetal tolerance | PNAS https://t.co/cuty2szEgj

[Sing Sing Way @babiesresearch]

Another twist to why babies more vulnerable to infection. Beyond immune cell immaturity, layering, active suppression... maternal pathogen-targeted antibodies still protect. Grateful @Nature for sharing this glass half-full perspective https://t.co/NmDlUluJzD

[nature @Nature]

Nature research paper: Natural maternal immunity protects neonates from Escherichia coli sepsis

https://t.co/apT1LTPORl

[Waggoner Lab @LabWaggoner]

Natural maternal immunity protects neonates from Escherichia coli sepsis @CincyImmunology
@CincyResearch @babiesresearch @Nature
https://t.co/JofjhQJhEA

[Ujjwal @ujjwaladh1]

Excited to see this work out in @Nature. Grateful to be a part of this team uncovering how maternal immunity help protect neonates from E.coli sepsis. Huge thanks to everyone who made this possible

[Sing Sing Way @babiesresearch]

Another twist to why babies more vulnerable to infection. Beyond immune cell immaturity, layering, active suppression... maternal pathogen-targeted antibodies still protect. Grateful @Nature for sharing this glass half-full perspective https://t.co/NmDlUluJzD

[Sing Sing Way @babiesresearch]

Thanks so much @CincyResearch for this post, and @theNAMedicine for highlighting the work we are doing to understand ways to improve infant and child health through improved pregnancy outcomes

[Ujjwal @ujjwaladh1]

Not all maternal microchimeric cells promote NIMA tolerance. Thanks to @babiesresearch for the opportunity to contribute on this paper @ImmunityCP

[Sing Sing Way @babiesresearch]

Tolerance to non-inherited maternal antigen is sustained by LysM+ CD11c+ maternal microchimeric cells: Immunity https://t.co/6SCuRsSQRh

[Ujjwal @ujjwaladh1]

@Messipokhrel @KaaLeKeeto Woah! Beautiful design

[Sing Sing Way @babiesresearch]

An elegant example for showing physiology of babies is unique and unlike little children and adults by @LabDeshmukh and @AlenghatLab with @jm_kinder. Thanks for letting us @babiesresearch join in the fun

[Ujjwal @ujjwaladh1]

Fresh out @AJPLung. Aging lungs exhibited heightened sensitivity to ozone, showing increased parenchymal damage and inflammatory responses compared to younger counterparts. Exciting work @X_got_worse. Glad to be a part of it #lungtoxicology #ozone

[AJP-Lung Cellular and Molecular Physiology @AJPLung]

This #OpenAcess #ArticleinPress is thanks to those at @uofupharmacy and @ChildrensPhila, Parenchymal and Inflammatory Responses to Ozone Exposure in the Aging Healthy and Surfactant Protein C Mutant Lung (Jenna Cheminant et al.):

https://t.co/xwV7X82R7K

#Aging #Ozone

[Sing Sing Way @babiesresearch]

Our research is expanding beyond pregnancy. Excited to share our results by @Hilmill1113 (https://t.co/VpTCnITP35) investigating transplantation tolerance; and grateful to @J_Immunol, @ImmunologyAAI for streamlined review and support

[Ujjwal @ujjwaladh1]

@MikeTyson Legend 🫡

[Ujjwal @ujjwaladh1]

Another hat of maternal microchimeric cells. Exciting work!

[Sing Sing Way @babiesresearch]

JCI - Complement-producing maternal microchimeric cells override infection susceptibility in complement-deficient murine offspring https://t.co/KBwDRNTUsE another example for what microchimeric cells can do, in this case offset disease severity associated with missing proteins

[Sing Sing Way @babiesresearch]

https://t.co/zzIHJKAU18 Besides persistence, another remarkable feature for microchimeric cells is their susceptibility to pregnancy induced displacement, and replacement by new fetal microchimeric cells. We don't know how this works, but does not seem to be classical rejection

[Ujjwal @ujjwaladh1]

@SaumyaTheGreat Wishing you a speedy recovery

[Ujjwal @ujjwaladh1]

@Lukeocyte_bio @metaBailism @SciImmunology Congratulations 🎉🍾

[Ujjwal @ujjwaladh1]

@SnoopDogg Smoke rejecting snoop or the other way?