This always gets me:
“The most valuable of all education is the ability to make yourself do the thing you have to do, when it has to be done, whether you like it or not.”
- Aldous Huxley
Krishna Rao is the CFO of Anthropic, and this is his first podcast appearance.
He joined the company two years ago when run-rate revenue was about $250M. Today it is $30B. He has helped raise ~$75B and is responsible for the procurement and allocation of compute.
I feel lucky we get to hear what it is like to sit inside a company this consequential at a moment this pivotal.
We discuss:
- The cone of uncertainty
- How he allocates compute across Trainium, TPUs, and GPUs
- What investors misunderstand about model companies
- Why the returns to frontier intelligence keep rising
- Platform vs application and where Anthropic builds its own products
- How Anthropic uses Claude internally
I have asked my closing question about the kindest thing more than 500 times. Krishna's answer is one I have never heard before.
Enjoy!
Timestamps:
0:00 Intro
2:38 The Compute Canvas
6:51 The "Cone of Uncertainty"
11:58 Why the Returns to Frontier Intelligence Are So High
16:45 Recursive Self-Improvement
20:20 Scaling Laws
23:30 Sourcing $100 Billion in Compute
28:05 Platform vs. Application Strategy
32:52 Pricing Dynamics
38:48 How Anthropic’s Finance Team Uses Claude
43:24 Raising Capital & Overcoming Investor Skepticism
52:32 Public Perception, Risks, and Government Regulation
57:25 Mythos Release
1:12:33 What Could Derail the AI Revolution?
1:13:47 Biotech and Healthcare
1:15:31 The Kindest Thing
No one made more money in trading than Jim Simons.
Not Buffett. Not Soros. Not Dalio.
His hedge fund was so powerful, he shut it down to outsiders.
$100 in 1988 grew to $400M in 30 years.
Here’s how a mathematician became the world’s greatest trader:
My high school tennis coach used to say:
“We win trophies in practice—we only go to tournaments to collect them.”
It’s the difference between amateurs and pros. 👇
In 2006, every section of Craigslist was a $1b marketplace startup waiting to happen.
In 2026, every section of PWC's website is a $10b AI startup waiting to happen.