Daniel Wacker

[Daniel Wacker @WackerLab]

Our latest work: As it turns out different positive allosteric modulators bind to different sites at the mu opioid receptor. Find out more in our @biorxivpreprint.
https://t.co/lorGBe427R

[Daniel Wacker @WackerLab]

A take on the current state of biased signaling in psychedelic action and psychedelic drug discovery by John McCorvy and I:

Biased Signaling in Psychedelic Action | Annual Reviews - https://t.co/AufgDcD6ZJ

[Daniel Wacker @WackerLab]

https://t.co/LpMiqFBSIG

[Daniel Wacker @WackerLab]

Job Alert! Open Postdoc position in membrane protein structural biology, molecular pharmacology @ drug discovery in New York.

More info can be found here: https://t.co/9V8fpZWvkQ

[Daniel Wacker @WackerLab]

Lessons from a Toad Psychedelic about the Role of different Serotonin Receptors in Psychedelic Physiology: https://t.co/pbVhYswK6C
Congrats to Audrey and @LankriDavidIL in this collab with @SamesLab and @ScottRusso published in @Nature

[Daniel Wacker @WackerLab]

Typo on my end: The study was spearheaded by @NeuroStructure

[Daniel Wacker @WackerLab]

Tetracyclic Antidepressants Activate Understudied Serotonin Receptors: https://t.co/EDlzMDSDOa
Congrats to @NeuroStruct, @Allyparp, and Audrey Warren for their study in @ScienceAdvances with help from @martafilizola, @NCCATinfo, and @GradSchoolSinai!

[Daniel Wacker @WackerLab]

Asenapine as a potent TAAR1 agonist

https://t.co/YEQ6UEOp4u

Congrats @NeuroStructure

[Daniel Wacker @WackerLab]

Tetracyclic antidepressants potently activate serotonin receptors 5-HT1e and 5-HT1F, explaining some of their clinically observed effects. @NeuroStructure @martafilizola @biorxivpreprint @biorxiv_neursci
https://t.co/ppFgWjHsE0

[Daniel Wacker @WackerLab]

Also, here is our @biorxivpreprint on the structure and pharmacological properties of human TAAR1
https://t.co/kxRxbx009x

[Daniel Wacker @WackerLab]

Also, the lab is looking for a Postdoc conducting the type of research described in the paper: CryoEM, membrane protein function and pharmacology, drug discovery.

[Daniel Wacker @WackerLab]

Structural Studies and Drug Discovery of SLC4A1/AE1 with @SchlessingerLab published in @NatureSMB: https://t.co/nIKYE6FUCo

[Daniel Wacker @WackerLab]

Thanks to first author @CapperMichael and collaborators including @SchlessingerLab, we report 7 structures, uptake and computational assays. Our mechanistic work complements the beautiful AE1-erythrocyte complex architecture reported by @OliBClarke. https://t.co/iY0stslKi6

[Daniel Wacker @WackerLab]

Sharing our @bioRxivpreprint of “Substrate Binding and Inhibition of the Anion Exchanger 1 Transporter”, in which we reveal how AE1 binds and transports substrates, and how different drugs inhibit the transporter.

[Marta Filizola @martafilizola]

Peer-reviewed version of ⁦@filizolalab1⁩’s ‘Mechanism of μ-Opioid Receptor-Magnesium Interaction and Positive Allosteric Modulation’ is now available on @biophysJ - ScienceDirect https://t.co/exocsT9Fpv

[Friedman Brain Institute @SinaiBrain]

EXCITING NEWS! Dr. Denise J. Cai receives prestigious @NIH Director’s New Innovator Award from the @NIH_CommonFund’s High-Risk, High-Reward Research program! A HUGE CONGRATULATIONS to @denisejcai on this great honor!🍾🎉🌟 PRESS RELEASE: https://t.co/JxQR16ppGg

[Daniel Wacker @WackerLab]

I am currently looking for a motivated Postdoc to join our team to work on the structure and function of neurotransmitter receptors and transporters. Spread the word! More info on our lab webpage https://t.co/zG2ouhxCQ8

[Patrick Giguere @TheGiguerelab]

Graduate student position available in my lab for highly motivated student!

[Cell @CellCellPress]

Online now at Cell: VEGAS as a Platform for Facile Directed Evolution in Mammalian Cells https://t.co/55GR6t84oT

[Daniel Wacker @WackerLab]

Now someone give @JustinGEnglish a real job already!

[Daniel Wacker @WackerLab]

Congratulations to my former colleague Justin English for his new paper in cell https://t.co/g0zG33SKUw