Christian Froekjaer Jensen

Assistant Professor @ KAUST. C. elegans genetic engineering and Synthetic Bio. Role of non-coding DNA in reducing epigenetic and transgenerational silencing.

[Christian Froekjaer Jensen @wormbuilder]

Big congrats to my Ph.D. student @FaisalMAlkhaldi for winning 1st place in the #LEAP24 Hackathon for his generative AI model to accelerate genetic engineering! #KAUST @KaustResearch

[lablab.ai @lablabai]

🏆Congratulations to the Top 5 onsite winners in the LEAP24 AI Oasis Hackathon!

🥇1st Place: Nuqta Genomics BioForge
Project: Accelerating Genetic Engineering

🥈2nd Place: Aures DAIT
Project: THE Diabetic AI Assistant

🥉3rd Place: Andromida
Project: WorthyYou

🏅4th Place: RAHA
Project: A voice-enabled AI for digital accessibility

🏅5th Place: Eventful
Project: AI Planner

They have won and joined the MVP Lab program by @ntdpsa , receiving a grant of 150,000 Saudi Riyals (40,000 US Dollars) to support and develop their winning ideas. 🚀

[Christian Froekjaer Jensen @wormbuilder]

@_mattrich 😆

[Christian Froekjaer Jensen @wormbuilder]

Excited that a talented Ph.D. student Mohammed Aljohani @MDJEditing from my lab is presenting his work on a genome-wide C. elegans CRISPR library for DNA and RNP-based CRISPR editing for the first time today at the CSHL CRISPR meeting.

[Christian Froekjaer Jensen @wormbuilder]

@ShahLabUCLA Thanks Pavak! Glad you got MosTI working quickly. We're scaling up the library integration approaches with the aim to find single-neuron promoters from oligo pools. Let me know if you have other applications you want to chat about.

[Ceron Lab @CeronLab]

😿Yesterday finished the Spanish Worm Meeting number VIII. #SWM2022

📶Our community is solid and the scientific level is rising.

🏅We were honored of hosting the Nobel laureate Andrew Fire and the superclass Christian Frokjaer-Jensen.

[Christian Froekjaer Jensen @wormbuilder]

@CeronLab @idibell_cat @segenetica Great to interact with the Spanish C. elegans community - lots of exciting science going on. Many thanks to the organizers for a well-planned conference.

[Christian Froekjaer Jensen @wormbuilder]

Very proud of Sarah AlHarbi (@SarahAlharbi_3), Ph.D. student in my lab and VP for Women in Science and Engineering Research at KAUST, for representing the university at Camp 2030 to work on UN SDG goals in New York. https://t.co/vZtK86vQZF

[Peter Meister @peter_meister]

Interested in chromatin folding/SMC complexes/nuclear organization and want to move the Switzerland for a post-doc? Switzerland has its own Marie-Curie postdoc program (deadline 01.12). Reach out by email if you look for a host lab! @snf_ch

[Christian Froekjaer Jensen @wormbuilder]

@AliciaLundby Congratulations Alicia! Great to see Berlingske do a story on your work.

[Christian Froekjaer Jensen @wormbuilder]

@farmgirlphd @Claycomb_Lab Congrats Julie & team! Thanks for the huge effort to make a reference. Oh, and @AGCharlesworth graphics really are beautiful. I am putting this panel up in the lab wall for reference.

[Christian Froekjaer Jensen @wormbuilder]

SGB lab members at the European Worm Meeting 2022!

[Christian Froekjaer Jensen @wormbuilder]

@CeronLab @sonia_elmouridi Thanks Julian. Give it a try and let us know what you think.

[Christian Froekjaer Jensen @wormbuilder]

1/7 Try our new app for optimizing transgenes for C. elegans expression (https://t.co/fFPIYVgnbB). The app uses algorithms from collaborators Henrik Bringmann (TU Dresden) and Dan Dickinson (UT Austin) - or codons from highly expressed ubiquitous genes.

[Christian Froekjaer Jensen @wormbuilder]

@ShahLabUCLA We should have called it "one-stop shop". That is the basic idea :)

[Christian Froekjaer Jensen @wormbuilder]

@Jordan_D_Ward Yes, the idea was to combine all the different steps we'd usually do sequentially - and a few things that I found myself doing "manually".

[Christian Froekjaer Jensen @wormbuilder]

@katic_i @ctmurphy1 Thanks Iskra. Please, let us know how it works out.

[Christian Froekjaer Jensen @wormbuilder]

@ShahLabUCLA Thanks Shah! We find that Dan's algorithm does really well if we combine with removing piRNAs. We didn't specifically add PATC introns (because they don't synthesize well) but we can add short introns with Golden-gate acceptor sites, if it's useful?

[Christian Froekjaer Jensen @wormbuilder]

7/7 The app was developed by postdoc Amhed Vargas (code, https://t.co/JGT66JC0kw) and transgene expression tested by @sonia_elmouridi. We'll write up the details but let us know if you find any bugs or have feature suggestions (no promises!).

[Christian Froekjaer Jensen @wormbuilder]

6/7 The optimized sequence is annotated in the app or in a GenBank file that can be opened in gene editors (for example @ApEplasmid)