MuSigma

[John Loeber 🎢 @johnloeber]

I'm noticing the growing possibility that Europe becomes very poor in the course of the next 10-20 years. You have the following factors:
- Heavy industry totally uncompetitive against China, automakers etc. rapidly losing ground
- Services industry totally uncompetitive against AI
- No natural resources, or regulatory hurdles making their extraction impossible
- No access to the new economy (no AI, no data centers, uncompetitive energy sector)
- Client states caught in one-way welfare ratchets, spend reallocation + investment well-nigh impossible

This seems under-contemplated. And we're talking really, seriously dirt poor: taken to its logical conclusion, many countries will have much, much smaller services and manufacturing industries -- economies may become much more heavily skewed toward natural resources and energy markets, where Europe has made it impossible for itself to compete.

And I'm not saying that this is likely to happen, it's an extreme case. But the probability is greater than zero and appears to be growing. The EV of that is so negative that it's surprising to me that it's not coming up more.

[BRICS News @BRICSinfo]

JUST IN: 🇶🇦🇺🇸 Qatar signs historic deal to import 4 million tons of American natural gas annually through 2054.

[Bloomberg @business]

Norway’s sovereign wealth fund said it’s among the investors that have been hurt by Turkey’s fund crisis, and has taken steps to review its stock holdings in the country. https://t.co/h5bZuqINbw

[The Economist @TheEconomist]

Prabowo Subianto’s erratic policies are holding back his country https://t.co/Ujvh4QQ8IB

[Avi Roy @agingroy]

Americans are flying to Shanghai for a lung cancer pill that the FDA approved 15 months ago.

Max Doppelt did it for his mother. Her lung cancer had spread to her brain. The drug most likely to help her, sunvozertinib, had been sold in China since 2023 but was unavailable in the US. So he flew over and came home with 26 boxes. Nineteen months later, she is alive and still working. He says at least 30 Americans have made the same trip.

In the trial behind the US approval, the pill shrank tumors in 46 out of every 100 patients whose cancer had worsened after chemotherapy.

The holdup is business, not medicine. Dizal, the Shanghai company that makes it, had no US sales network, according to US oncologists in May. AstraZeneca licensed the drug in July for $600 million and says US sales will start this quarter.

An @FDA approval helps American patients only when a company actually sells the drug here.

[BitBeller 🐶 @BitBeller]

Ich bin vor drei Wochen nach Prag ausgewandert.

Wer Deutschland verlässt, muss sich innerhalb von zwei Wochen abmelden, sonst gibt's ein Bußgeld. Also hab ich direkt online einen Termin beim Bürgeramt gebucht.

Nächster freier Termin: in neun Wochen.

Okay, dann eben Spontantermin. Ich stand um 7:30 Uhr vorm Bürgeramt. Vor mir 6 bis 7 Leute. Mit Klappstühlen. Eine Frau hatte eine Thermoskanne und ein Kreuzworträtselheft dabei, die war offensichtlich nicht zum ersten Mal hier.

Um 7:58 Uhr kommt ein Mann raus und klebt einen Zettel an die Tür: „Heute keine Spontantermine wegen Systemumstellung."

Die Frau mit der Thermoskanne hat nur genickt und ihr Rätselheft eingepackt. Als wäre das ein ganz normaler Dienstag.

Nach meinem Umzug habe ich dort angerufen. 47 Minuten Warteschleife. Dann: „Sie können sich auch per Fax abmelden."

Ich bin in Prag in eine Apotheke gegangen und hab gefragt, ob ich da was faxen kann. Die Apothekerin hat mich angeschaut, als hätte ich nach einem Telegramm gefragt. Sie hat es dann gemacht, wahrscheinlich aus Mitleid.

Soweit so gut.

Eine Woche später ruf ich wieder an. „Das Fax ist angekommen. Aber wir brauchen die Unterschrift im Original."

Warum gibt es dann die Fax-Option?

„Das kann ich Ihnen nicht sagen."

Also bin ich zurück nach Deutschland gefahren. Fünf Stunden. 6:30 Uhr vorm Bürgeramt. Diesmal hat es geklappt.

Die Sachbearbeiterin tippt alles ein, stempelt, druckt die Abmeldebescheinigung aus, perfekt. Ich will gerade aufstehen.

„Ach, Moment. Sie sind ja schon seit drei Wochen weg. Die Frist ist zwei Wochen. Das ist eine Ordnungswidrigkeit, das muss ich weitergeben."

Ich hab ihr erklärt, dass ich am ersten Tag einen Termin gebucht habe und das Bürgeramt mir einfach keinen früheren gegeben hat.

Sie hat mich ganz ruhig angeschaut und gesagt: „Das ist nicht mein Problem und außerdem bin ich dafür nicht zuständig."

Gestern kam der Bußgeldbescheid: 35 Euro.

An meine neue Adresse in Prag. Hier sind die natürlich ganz schnell.

Das ist das beste Deutschland aller Zeiten.

[Inclusive Productivity Network @incprodmon]

Very valuable!

"Industrial AI: from Pilot to Profit: Key Concepts, Success Factors, Use Cases and Market Mechanics" by Boris Scharinger.

https://t.co/93xKLWswcv

"Industrial AI: from Pilot to Profit provides comprehensive insights for riding the AI wave, despite the uncompromising realities of industrial environments. Whether directing a startup strategy or launching corporate AI initiatives, this book is instrumental in steering teams towards successful industrial-grade AI approaches."

Marco Huber (University of Stuttgart and Fraunhofer Institute for Manufacturing Engineering and Automation IPA): “This book powerfully demonstrates how AI creates real value in industrial practice. With its extraordinary range of application areas and tangible use cases, it serves as a unique source of inspiration for decision-makers and users alike. Anyone seeking to understand how AI actually works in a business setting and how it can be implemented will find this an indispensable reference work.”

https://t.co/93xKLWswcv

[Elaine🇺🇸 @PatriotEmma47]

🚨BREAKING: New York Police Officer Quathisha Epps made over 400,000 dollars last year with a base salary of 204,000 and another 204,000 in overtime.

She claimed to have worked over 1,600 hours of overtime and is now under internal affairs investigation for allegedly falsifying overtime hours, including self-approving her own time slips.

Despite the probe, she was allowed to retire early and is now receiving roughly 16,000 dollars per month from taxpayers in her pension.

[The Pleb 🇨🇦 @truckdriverpleb]

Indian newcomer in Canada teaches his followers how to steal "free" food that was intended for poor Canadians

These people are not compatible with our culture whatsoever. These are the complete opposite of Canadian values

DEPORT!

[max doppelt @maxdoppelt]

In January 2025 my mom’s lung cancer spread to her brain. The drug with the best chance of helping her was approved in China but not here.

A doctor told me, almost as an aside, that if she were Chinese she could buy it at a pharmacy.

So I flew to Shanghai and came home with 26 boxes in my luggage. That was 19 months ago. My mom is still here, still working, and in her words has had an amazing three years.

The drug was approved in China in 2023. The FDA approved it in July 2025. It still is not for sale here. I know of at least 30 Americans who have made the same trip.

I have been scared to tell this story because I worried it could cost my mom access to the medicine keeping her alive. But the problem matters more than my silence. These drugs need to be developed and available here, and that means FDA reform.

Art Allen at KFF Health News told our story this week. It also ran in The Washington Post.
https://t.co/tHKV3L004L

[Dan Collins @DanCollins2011]

Americans are smuggling Chinese cancer medications in their suitcase.

26 boxes of Zeggrovy will cost you $10k in China.

AstraZeneca licensed it from the. Chinese company and is projected to sell it around $200k for the 26 boxes.

We don’t have to live like this.

[Treasury Secretary Scott Bessent @SecScottBessent]

Before: tankers filled Iran’s main oil-loading terminal.
After: no crude tankers in sight.

Kharg Island is now nothing more than a monument to the one thing the Iranian regime can still produce: failure.

The regime’s arrogance and belligerence continue to punish ordinary Iranians. Operation Economic Outcast is cutting off the regime’s oil lifeline, denying it resources to fund terrorism, nuclear procurement, and the lavish lifestyles of the IRGC elite.

[LayoffHedge @LayoffAI]

7% GROWTH IN INDIA. THEY CAN THANK AMERICAN PAYROLL.

India now has at least 2,117 offshore capability centers employing about 2.36 million people.

Microsoft pledged $17.5 billion there in December. Amazon pledged $35B more through 2030.

This list is the tip of the iceberg.

[BBC News (World) @BBCWorld]

Crowd of 50 beats foreigner to death in South Africa https://t.co/lNWxzHZRu2

[The Information @theinformation]

Exclusive: DeepSeek is helping Huawei design its next generation of AI chips, with Huawei engineers working inside DeepSeek’s offices.

The collaboration could help China train advanced AI models without relying on Nvidia.

Read more: https://t.co/zbG09YJRNR

[겨울 @4n0m1ex]

한국이 20년간 몽골을 도와 조성한 초원이 너희의 경솔함 때문에 80%가 탔어. 중국이 인공강우를 뿌리지 않았다면 아예 전소 됐을거야. 동아시아에 전방위적인 민폐를 끼쳐놓고 아직도 남탓이나 하고 있니? 너 같은 애들 때문에 다른 일본인들이 고개 숙이고 사과하고 다니는 거잖아.

[The Washington Post @washingtonpost]

Exclusive: The Pentagon is looking to build a more robust deep-cover spying program to conduct economic warfare against China and other U.S. competitors, according to people familiar with the initiative. https://t.co/t4aLnUsZA9

[朝日新聞(asahi shimbun） @asahi]

モンゴルで大規模な草原火災　KDDI現地子会社の車から出火か https://t.co/BphpQWnWrQ

モンゴル国営放送によると、モンゴル東部ドルノド県で今月8日に大規模な草原火災が発生し、自然保護区を含む計52万8765.5ヘクタールが被災した。

[The Economist @TheEconomist]

Private research institutions argue that they are building the future of science, not universities. The history of American innovation suggests they may be right https://t.co/Xx1W3mt8Ih

Illustration: Carl Godfrey

[Bloomberg @business]

The UK was once a pioneer of rail technology. Now, it has one of the worst electrification rates in the world. This week on Bloomberg Green's Zero podcast, how battery-electric trains could change the game https://t.co/AKKarsR3Yy