After 'how to be creative', 'how to write a great paper', 'how to write a bad paper', we can now start with 'how to make to the top of the QED charts'. We are doing really well. Science? Who cares if we can all be creative and aim for this 1%!
Happy to share our new preprint: Spatial Rewiring of Enterocyte Identity in Celiac Disease https://t.co/tfw3wD6Lsr. We describe unexpected changes in enterocyte zonation in Celiac Disease.
(1/8) Still wondering how low complexity intrinsically disordered regions (IDRs) guide transcription factors (TFs) to bind in genomes? Previous studies on sequence grammars; our new @MolCell paper takes the next step: de novo design of functional TF IDRs!
https://t.co/qJugw2V3qE
So you sequenced a billion+ bases. That don’t impress me much.
Over the last decade, biologists have learned how to generate genome sequences at extraordinary scale. What hasn’t kept pace is figuring out what those genes actually do.
Today we infer what a gene by computing similarities, whether by sequence or by structure. Incredibly useful for a first pass but not good enough in most cases to understand or engineer biology. You have to modify the genes and measure the consequences to know what they do.
JERBOA is a toolkit to figure out what genes do at scale. We've used it to unlock 43 non-model microbes across 12 different phyla.
Molecular assets on @Addgene. Analysis software on @github. There's so much to explore, get out there!!
Our new paper is out @Nature 🎉. We show that m1Ψ in mRNA vaccines doesn’t just quiet immunity, it also directly enhance translation by reshaping ribosome dynamics in a sequence-dependent way 🧬
Full paper : https://t.co/T0V5IsVDHj
Huge kudos to @WeizmannScience's @Sys_Immunology Yifat Merbl, included in @Nature's 10.
This scientist found a new trick of the immune system by digging through cellular rubbish https://t.co/yEfSQc3XfB
Some companies try to break plastic. We broke open the microbe that eats it.
The bacterium that naturally degrades PET bottles has been un-engineerable for years. We @CultivariumFRO set out to change that.
"It's just a temporary space until your lab is renovated", Weizmann Institute version. Rebuilding better, and doing so fast. (Photo and tagline: Ziv Shulman)
EEE meeting is BACK! Early Embryogenesis & Epigenetics conference in Berlin 02/2026.
Checkout great program and over 12 slots for (not so) short talks for submitted abstracts!. Early registration now open - https://t.co/XZIEGUV11v
Congratulations to Profs. Assaf Vardi, Steffen Jung, Oren Schuldiner & Yonatan Stelzer of upon being elected as members of @EMBO@lab_oren @TheJungLab @VardiLab
This is what’s left of my lab😞. Finally heading back home. I need to stand, with my two legs, in front of the rubble that was just a few days - my thriving lab, a home for excellent Israeli Jews and arab, as well as foreigners students. This will be my first step of acceptance.
📣Announcing the 2025 Laureates 🥇🥇🥇 of the @Blavatnikawards in Israel! Congratulations to Benjamin Palmer @bengurionu, Chaim Garfinkel @HebrewU, Yonatan Stelzer @WeizmannScience! Each will receive US$100,000 for their groundbreaking scientific research: https://t.co/ALFm3Ri4gc
Congratulations to Prof. Yonatan Stelzer of the Department of Molecular Cell Biology, upon being awarded the 2025 @BlavatnikAwards for Young Scientists
לא לדאוג, אני בסדר. אחרי 38 שנים בצה”ל, כמה דחיפות לא יעצרו אותי ואותנו.
עכשיו - ממשיכים להיאבק, לא עוצרים לרגע. עוצרים את ההפיכה. מחזירים את החטופים.
אחר כך מחליפים את השלטון, מחזירים את המדינה מהידיים של מושחתים, משתמטים וכושלים - לידי העם. רק במאבק נחוש, כשכולנו ברחובות, רק כך נאבק, רק כך ננצח.
New immune mechanism revealed in the Cellular Trash. The discovery, led by Prof. Yifat Merbl’s lab, holds promise in light of the growing resistance to antibiotics >> https://t.co/zn3M8WX0hw @YMerbl@Sys_Immunology
We offer three new positions to join BCA @MooreFound:
1. A full-stack developer to work on the BCA database with @emblebi
2. A senior research technician to develop sc methods
3. A bioinformatician to analyze new atlases with @SangerToL
Details below.
Please, share and repost.