RS

Cynic, sarcastic, and inquisitive. Can't stand hypocrites. And can't resist a good joke, which most of our world is nowadays. Laugh and let live.

[RS @zanyrutvik]

@IndiasWorld_mag @marc_saxer Will this be available for attending online?

[RS @zanyrutvik]

@MartinShkreli @thevraa Why not? It will great to understand.

[RS @zanyrutvik]

@amazonIN what's with removing ad free & downloads from prime music when my annual subscription just started? I renewed basis the services promised & now you ask to pay more for what I've already paid? Is it fair to do once we've paid - when you can easily do it at next renewal!

[RS @zanyrutvik]

@sujit_bangar For any significant transaction it is better that spouse who hasn't paid files the tax return for that year. This will enable dept to send query on which the PAN of spouse who has paid can be mentioned. Assessment has been avoided in such cases. But if it comes docs are a must.

[olee.space @Olee_space]

We just delivered India’s first Directed Energy Weapon.

<$1 per shot. Unlimited ammo. Sub-3s hard kill.

Built in a Pune warehouse by a team that wasn’t supposed to exist.

$150K per-shot interceptors? Obsolete.

#DefenceTech #IndiaTech #DirectedEnergy #CounterUAS #MakeInIndia

[RS @zanyrutvik]

@VishalDayama 2 minutes silence for those who did not receive the heart attack inducing message - they don't know where they fall - defaulter of phone bill, or foreign citizen, or both!

[RS @zanyrutvik]

@shahnisarg @vee22n Wow! Have been searching them for ages and can't find them anywhere. Such nostalgia they bring!

[RS @zanyrutvik]

@MTPHereToHelp My sister is stuck at Mankhurd since last 3 hours with no police presence at all. At least open a lane by which they can take a u turn and get out!

[RS @zanyrutvik]

@Riazi_Cafe_en Didn't expect the missing pages to be the first of his perplexing problems!

[RS @zanyrutvik]

@MinervaCap Good observation. My probability of the resolution would be even lower. The telling point is Israel isn't part of this break in hostilities fully. And they've been the one setting the contours of this War.

[RS @zanyrutvik]

Good list for all types and ages of math fans or learners. Quite a few good resources, some of them free to use.

[Cliff Pickover @pickover]

Mathematics.

The Cambridge List of suggested math books for passionate explorers of all ages. PDF link: https://t.co/Vs2pHoE6iZ

[Cliff Pickover @pickover]

Mathematics.

The Cambridge List of suggested math books for passionate explorers of all ages. PDF link: https://t.co/Vs2pHoE6iZ

[RS @zanyrutvik]

@bookworm_Kris Way to go! Some good recommendations for my kids!

[Swarajya @SwarajyaMag]

Several years ago, engineers at a major Indian OEM wanted to add a simple valve to their own engine.

They knew how to do it. The problem: the software running inside their own vehicle's ECU was locked. The key was in Germany.

Three years later, the problem remained unsolved. 🧵

[Anish Moonka @anishmoonka]

Every time you get a cancer biopsy, the lab makes a tissue slide that costs about $5. It shows the shape of your cells under a microscope, and every cancer patient already has one on file.

There’s a much fancier version of that test called multiplex immunofluorescence (basically a protein-level map showing which immune cells are near your tumor and what they’re doing). It costs thousands of dollars per sample, takes specialized equipment most hospitals don’t have, and barely scales. But it’s the kind of data oncologists need to figure out whether immunotherapy will actually work for you. Right now, only about 20 to 40% of cancer patients respond to immunotherapy, and one of the biggest reasons is that doctors can’t easily tell whether a tumor is “hot” (immune cells actively fighting it) or “cold” (immune system ignoring it).

Microsoft, Providence Health, and the University of Washington trained an AI to analyze the $5 slide and predict what the expensive test would show across 21 different protein markers. They called it GigaTIME, trained it on 40 million cells in which both the cheap slide and the expensive test coexisted, and then turned it loose on 14,256 real cancer patients across 51 hospitals in 7 US states.

The results landed in Cell, one of the most selective journals in biology. The model generated about 300,000 virtual protein maps covering 24 cancer types and 306 subtypes. It found 1,234 real, verified connections between immune cell behavior, genetic mutations, tumor staging, and patient survival that were previously invisible at this scale. When they tested it against a completely separate database of 10,200 cancer patients, the results matched up almost perfectly (0.88 out of 1.0 agreement).

Nature Methods named spatial proteomics (mapping where specific proteins sit inside your tissue) its Method of the Year in 2024, and specifically cited GigaTIME in a March 2026 update as a model that “democratizes” this kind of analysis. The full model is open-source on Hugging Face. Any cancer research lab with archived biopsy slides, and most of them have thousands, can now run virtual immune profiling without buying a single piece of new equipment.

[RS @zanyrutvik]

@RBI @UPI_NPCI just made a payment in Sri Lanka using UPI with on the fly conversion! One activation and I was set to pay in a few seconds! Amazing stuff!! Now only if the forex conversion rate can be lowered!

[RS @zanyrutvik]

@SurajKrBauddh @elonmusk and you say reaching Mars is difficult. Get him on your team asap!!

[Mumbai Rains @rushikesh_agre_]

🚨 Mumbai Metro Line-4 concrete slab has fallen on cars below on LBS Marg, Mulund West near Johnson & Johnson/Oberoi. 1:15 PM.

Immediate site safety action needed. @MMRDAOfficial @mybmc @MTPHereToHelp

[RS @zanyrutvik]

@Ola_Mumbai why can't I find any way to connect with support from the app?? Your support options are lacking and except for emergency there's no way to connect with support to explain the issue?? @Olacabs @AshwiniVaishnaw

[RS @zanyrutvik]

@mybmc why is the Bombay Central railway flyover not opened to public even though pretty much ready since 2 weeks! @Dev_Fadnavis @mid_day @RoadsOfMumbai