We usually think of mRNAs carrying the information needed to make a protein (the central dogma...). But how can the encoded protein control the fate of its encoding mRNA? 🤔
Check out our review on the topic 👇
https://t.co/vqj5JHzWbJ
If you agree that ERC should remove their academic age limits on ERC grants - please Sign this Petition! Please also RT: #EDI#science#EuropeanScience#ERCgrant https://t.co/ydFU97qdju via @UKChange
🚨preprint alert🚨
What do cells do if there's too much tubulin around? They get rid of the encoding mRNAs! Check out the mechanism for ribosome-associated tubulin mRNA decay 👇
Excellent collaboration with @AbsmeierEva@lapassmore@Ivana_Gasic!
https://t.co/RjRxsA2ADa
New work from @_M_Carminati shows that dephosphorylation of RNA polymerase II by CPF (the 3' end processing machinery) promotes Pol II dimerisation. @mcemremnv @MRC_LMB @ERC_Research
PolyA tails on eukaryotic mRNAs are added after co-transcriptional endonucleolytic cleavage of the pre-mRNA.
@VBoreikaite has now reconstituted specific and efficient 3ʹ-endonuclease activity by human CPSF with purified proteins. @ERC_Research @MRC_LMB https://t.co/cZGdvu4odW
We solved a long-standing question about the precise role of the NSUN4 RNA methyltransferase in mitochondria.
A fantastic collaboration between @BurtonNick @ericmiskalab from the @GurdonInstitute and the Venki Ramakrishnan group @MRC_LMB @_nirupa_desai@Hanting_Yang
In a new Science study, researchers present #RoseTTAFold—an #AI network that produces structure predictions with accuracies approaching those of DeepMind’s AlphaFold2. The tool’s code is freely available.
Read more: https://t.co/602WVNVaR3
Yesterday, the German Society for Crystallography (DGK) awarded Manfred Weiss @ManfredSWeiss with the Will-Kleber Medal 2021 for his methododological developments in crystallogrpahy. Congratulations.
@HZB @HZB_BESSY