Mitral Valve Prolapse and Ventricular Arrhythmia Risk in TTN-Mediated Cardiomyopathy: A Single Center Experience
@roxanne_coderre@swain_willMD@JohnGiudicessi
https://t.co/2CeM4DhtZy
Dr. Ochi from our EP team has published an important paper!
Excessive ablation for paroxysmal AF may increase the risk of heart failure over 7 years of follow-up, potentially due to impaired atrial function.
More ablation is not always better!
Maintenance of V1-LBBAP Paced QRS Morphology (or a paced QRS ≤120 ms [PlusQRS]) and Response to LBBAP-CRT: Secondary Analysis CONSYST Trial 🟦🟩 JACCEP @JACCJournals
* With strict criteria at implant
@MarionaRegany@JlmontGirbau@tolosanaviu
https://t.co/dzcH1A9j0n
PFA often fails to transmurally block the mitral isthmus or denervate the Vein of Marshall. VOM ethanol infusion remains useful #EPeeps#AFib@patelapoor@NileshMathuria https://t.co/6wyLhhoX0t
Latest crazy story from the frontiers of math and AI -- a neurosurgery resident, with no training in advanced math, uses ChatGPT 5.6 to solve a major open problem in numerical linear algebra. https://t.co/xckiv4TCFc
#AFib is caused by atrial inflammation, and right atrial appendages from patients with AF express higher SGLT2 & GLP-1R. Read about how treating both targets could be synergistic in preventing AF-associated atrial myopathy. https://t.co/Oky8tCYV5F
#JACCBTS#SGLT2i#GLP1R#cvPrev
Sascha Goonewardena and I are hiring five people into our joint cardiovascular AI and multi-omics program at Michigan — postdoc, two senior data scientists, a clinical research coordinator, and a proteomics/biospecimen specialist.
Our labs study coronary microvascular disease and cardiometabolic risk using cardiac imaging, high-throughput multi-omics, and machine learning. These roles span the full width of that: sample handling, model development, and first-author discovery work.
RESEARCH
Postdoctoral Research Fellow — Multiomics and Causal Inference
Hypothesis-driven discovery: multi-omic analyses in large prospective cohorts, Mendelian randomization and mediation analysis at biobank scale, first-author manuscripts. Doctoral degree required.
COMPUTATIONAL
Senior Data Scientist — AI and ECG
Deep learning foundation models for ECG-based detection and endotyping of cardiometabolic disease, and the data infrastructure behind them. Transformers, self-supervised pretraining, PyTorch, large-scale waveform harmonization.
Senior Data Scientist — Multiomics and Population Cohorts
Multi-omic analysis pipelines, model inference deployed across population biobanks, cross-cohort harmonization. Olink or SomaScan, R or Python, causal and genetic inference.
OPERATIONS
Clinical Research Coordinator — Senior/Intermediate
Regulatory management and participant-facing operations for the cardiovascular biorepository: IRB submissions, recruitment and study visits, REDCap workflows, mentorship of junior coordinators.
Proteomics and Biospecimen Research Specialist
Technical lead for the biospecimen pipeline, from collection and biobanking through high-throughput assay coordination, quality control, and vendor management.
All five sit in the Division of Cardiovascular Medicine. Applications go through the U-M careers site; prospective postdocs are also welcome to write to either of us directly with a CV.
🔗https://t.co/0HtJIR1JU0
In this multicenter VT ablation registry, a novel temperature-guided ablation modality showed favorable safety and efficacy relative to power-controlled ablation.
Get the details in #JACCCEP: https://t.co/qgcSyHzCbv
#EPeeps#epAblation@CompagnucciMd
In moderate-severe secondary #TR & #AFib, rhythm control w/out AF recurrence was linked to 3.65-fold improvement of TR to ≤mild. Rhythm control may help mitigate TR severity; consider before TR intervention. https://t.co/yZ0SKoDIf1
#JACCIMG#vhdTR@MayoClinicCV@konsiont
In this sham-controlled trial of 60 patients with symptomatic atrial fibrillation, pulsed field ablation (PFA) was superior to sham in reducing arrhythmia recurrence & burden and improving QOL. https://t.co/iZqzeZILK7
Important paper for all PFA users!🚩
PFA-PVI may look successful—but tiny signals matter.
Residual tiny PV potentials ≥0.03mV ⚡️on high-res mapping predicted 1-yr AF/AT recurrence + late PV reconnection (81% spatial concordance).
Do not miss tiny signals.🔍
https://t.co/MbT8cqZ5ZK
@masudamasaha@hrs_journal
#EPeeps #PFA #AFib