The transcription factor Pax5 regulates #Bcell development & commitment, and scientists in the lab of Meinrad Busslinger have found out how. Out now in @JExpMed!
Our interview with first author @SarahGruenb 👉🏼 https://t.co/T4QePv7PlU
The paper 👉🏼 https://t.co/5OP45wMQg3
Delighted to announce the publication of my PhD work in @JExpMed! 🧬 We delved into Pax5 domains, emphasizing CRD1 & CRD2 being pivotal for B cell development and commitment. For more insights, read here: https://t.co/VDCLQQ8ewL
#PhDResearch#BCellDevelopment#Immunology 🎓
It was a pleasure to write with @VassilisGlaros a preview of beautiful work by @robinsonmarcusj /#Tarlintonlab. We tried to see it as minireview of all recent plasma cell timestamping studies by Kurosaki/Ise, @Qi_Tsinghua@DinisCalado and @FooksmanLab labs
https://t.co/9NwqMhR5JG
Local enhancers of the #PAIR4 regulatory module promote distal V-H gene #recombination at the #Igh locus and contribute to #Bcell receptor repertoire diversification
@Louisa_Hill_ et al Busslinger lab @IMPvienna
https://t.co/YHSE4NbLHY
Very happy to share that the last part of my PhD work with Meinrad Busslinger on the role of the PAIR regulatory module in VH gene recombination is out @embojournal ! 🤩🎉🎆
Read 👇 how these enhancers help to generate a broad antibody repertoire:
https://t.co/z1KFk1YLib
It's a wrap! I am thrilled to share that I am now a proud holder of a PhD! A special shoutout to the people who accompanied me throughout this journey! Here's to the start of a new chapter!
I'm super excited that our latest paper was published in Frontiers of Immunology today. Big thanks to Theresa Pinter, the Busslinger and the @johannes_zuber lab and the @IMPvienna
Do you have a favorite gene? Check out if it's essential for plasmablasts
https://t.co/D8ZHRPt26a
An team of scientists of IMP & @erasmusmcintl discovered a link between transcription factor #PAX5 & both #Bcell & brain development/#ASD. Now in @JExpMed:
https://t.co/UMO03NLatM
News item: https://t.co/gBewpupsT5
#autism#Immunology
I am beyond excited to see our story published @JExpMed ! It was a fantastic collaboration with outstanding clinicians and scientists but specifically with Fabian Kaiser and @AleksBadura at @ErasmusMC!
Give it a read to see how Pax5 is important in #Bcells and #braindevelopment!
We are looking for a postdoc to join an extremely exciting project! Do you want to know what #gdTcells recognize? To investigate function of a novel gdTCR ligand candidate? To understand what gdT-TILs recognize in tumors? Join us @karolinskainst! Pls RT.
https://t.co/If2ZomVFv8
The lab of Meinrad Busslinger at the IMP and @TKreslavsky@karolinskainst unveil the role of Bhlhe40 in downregulating the #germinalcenter reaction and preventing #lymphoma development. Congratulations to all authors! Read along 👇
https://t.co/VNqv0dpg07
A round of applause to @Louisa_Hill_ for winning the Kirsten Peter Rabitsch Award for her exceptional PhD thesis: "Factors and regulatory elements controlling #immunoglobulin locus contraction during V(D)J recombination" 🎓👏🏾
https://t.co/4DNVXFzsTR
For decades, Meinrad Busslinger's lab has studied how #Pax5 steers #Bcell development. In @SciImmunology, @CalderonLesly & others now show that Pax5 is also key for *sustaining mature* B cells & their function.
https://t.co/5H6ZE1ouSb
https://t.co/9YX6PEo5ju
Repression of the B cell identity factor Pax5 is not required for plasma cell development. A new study by Grace Liu @gracejliu, Meinrad Busslinger @IMPvienna, Bergthaler @abergthaler@Bergthalerlab, and colleagues. https://t.co/yYvLnnza11 #Bcell#PlasmaCell
My second article is brought to you by Metropole! This story inspired me, not only for its cool breakthrough in COVID-19 testing, but also by the determination of the PhD students who worked through lockdown to drive this innovation! #IMP#IMBA#VBC https://t.co/NGqgXRZRRl