@SKabrajiMD@utswcancer@RoswellPark@theNCI Definitely a step up from pre-rounding on paper charts or 36-hour MICU call. It's really fun, excited to see what we find out!
1/ Excited to share our new paper with @SihanSean@utswcancer@CRI_UTSW and Michael Lawrence @MGH_RI, now online @CD_AACR. Led by Shreoshi Pal Choudhuri, we found that ecDNAs with MYC paralogs drive acquired cross-resistance in small cell lung cancer #SCLC
https://t.co/MraxEM6PKb
@jillianmcwise@stanleylim93@HFarsibaf@MarcelloStanzi1 @cbmeador 8/ We are grateful to the patients who participated in this research, to @MGHThoracicOnc, and to our funding. This project was launched with @AnnaFaragoMD, guided by Nick Dyson, and inspired by Bruce Johnson, Adi Gazdar and John Minna, who figured most of it out in the 1980's.
7/ We conclude that ecMYC/L/N are recurrent drivers of cross-resistance in SCLC. Shreoshi led a team effort from @jillianmcwise Dr. Luc Girard @stanleylim93@Hfarsibaf@MarcelloStanzi1 @cbmeador, and many others without twitter handles.