What if you could watch chromatin states change inside living neurons.....IN REAL TIME? Repost or share if you or someone you know dreams of this!
The Solecki Lab is building an imaging-based biosensor platform to make chromatin biology visible, measurable, and experimentally testable as neurons mature and wire into brain circuits (see enhancer nucleosomes fluttering below).
We’re looking for an Associate Scientist who wants to do more than run experiments. Someone who wants to help build the framework for seeing how the neuronal genome changes as the brain is built.
What if you could watch chromatin states change inside living neurons.....IN REAL TIME? Repost or share if you or someone you know dreams of this!
The Solecki Lab is building an imaging-based biosensor platform to make chromatin biology visible, measurable, and experimentally testable as neurons mature and wire into brain circuits (see enhancer nucleosomes fluttering below).
We’re looking for an Associate Scientist who wants to do more than run experiments. Someone who wants to help build the framework for seeing how the neuronal genome changes as the brain is built.
Still one of the purest dopamine hits in science:
Thank you for your submission.
For one brief, beautiful moment… the paper is someone else’s problem.
Reviewer 2 can cook me later. 🔥
Mind-blowing cell action alert!
Watching vesicle cargo lanes light up like a
@FedEx highway in real-time under the #microscope.
Who knew that home-brewed phosphatidic acid live cell imaging probe would look so stunning in human fibroblasts?
Which organelle do you think its labeling? Drop your guess below!
Too late for #FluorescenceFriday but just in time for #MicroscopyMonday #scicomm #sciart #Science
Hey y’all 👋 I need a little repost magic. 🔥
The Solecki lab is recruiting MULTIPLE postdocs for a chromatin imaging project at St. Jude.
This work sits at the intersection of live-cell imaging, neuronal cell biology, chromatin regulation, and quantitative image analysis — and the eye-popping video below shows exactly why it’s so exciting.
This may be for you if you are:
• A neurobiologist who wants to become DANGEROUS in cell biology 🧠
• A chromatin biologist who wants to ditch endpoint molecular biology and actually watch nuclear states unfold in living cells 🧬
• An imaging scientist or biophysicist who wants to get messy in real cells, not idealized samples 🔬
A quantitative mindset is required. Prior experience in every area is not.
If you ever imagined touring the nucleus like nuclear render and our Pol II biosensor below… reach out because WE can do it.
Tag a scientist who needs to see this + RT to help us find them! 🚀 Let’s make chromatin biology history.
Very excited and proud to announce Dr. Kristen Thomas and my new paper on synaptic plasticity mechanisms in fused, human-derived thalamocortical #organoids out in @CellReports this week! (1/5)
#MachineLearning techniques have the potential to handle huge amounts of data and uncover sound patterns, allowing for faster, cheaper, and better ecological studies based on acoustics.
Learn more in a new #SciencePerspective: https://t.co/4MP9esF0Pp
Beyond thrilled to finally share our preprint, where we have found that Uridine Phosphorylase-1 supports metastasis of mammary cancer by altering immune and extracellular matrix landscapes of the lung https://t.co/k6a0CfMVci
#UPP1#cancermetabolism#metastasis (1/13)
My postdoc work is FINALLY out in @NatureComm!🙌🏾 AgRP neurons control appetite, but their transcriptional regulation is a mystery. Here, we generated AgRP neuron RNA-seq & ATAC-seq profiles and show that IRF3 mediates leptin’s hunger-suppressing effects
https://t.co/EPf2OGSUL7