Elijah Edmondson

[Elijah Edmondson @ElijahEdmondson]

CD4+ T cells recognize tumor antigens & trigger vascular damage via macrophages, starving tumors of blood supply. Exciting insight into immunosurveillance & potential new therapeutic angles! @ScienceMagazine https://t.co/MZqbjN4C5u

[NASA Administrator Jared Isaacman @NASAAdmin]

To return Americans to the Moon, NASA is shifting to an iterative, execution-focused approach – just as we did during Apollo. 

We are standardizing rocket architecture, embedding NASA expertise across industry, and increasing launch cadence to support sustained lunar operations.  

We are sending a demand signal for crewed missions beyond Artemis V, with at least two providers capable of bringing astronauts to the surface every 6 months. 

The goal is not just to reach the Moon, but to stay. 

America will never give up the Moon again.

[Elon Musk @elonmusk]

Starship V3 first flight in about 4 weeks

[mark bissell @MarkMBissell]

got my whole genome sequenced and uploaded it to our research cluster where we've got a bunch of bioinformatics tools for claude code

also gave claude access to the nano banana API

"tell me what I look like based on my genome"

left: high school me
right: claude + NB output

[Elijah Edmondson @ElijahEdmondson]

https://t.co/f5vRoOtavk SpatialQM + ST Portal -> reproducible, comparable spatial transcriptomics.

[Association for Single Cell Analysis @ascanet]

Yesh Datar ... Patrick Ellinor constructed HeartMap, the largest single-nucleus atlas to study human adult heart disease ➡️ https://t.co/8ut9PrASdF

#SingleCell #SpatialBiology

[Hao Yin @HaoYin20]

Comparing single-cell #SpatialTranscriptomics methods on FFPE human tumor #TissueMicroArray

CosMx 1k vs MERFISH 500 vs Xenium-UM/-MM 339
93 common genes

lung adenocarcinoma
pleural mesothelioma

Corr. Bulk RNAseq, GeoMx

"better F1-scores with Xenium-MM (median, > 75%) than other ST platforms for all cell types"

@kchenken @NatureComms 2025
https://t.co/nU97JztUuN

[NIH @NIH]

BREAKING NEWS❗

NIH establishes nation's first dedicated organoid development center to reduce reliance on animal modeling. https://t.co/8JP6jGUyzS

[Christophe Leterrier @christlet]

Are exocytic events happening in holes of the spectrin scaffold? To check this, we developed live-cell/SMLM correlative imaging to link exocytic sites to their nanoscale environment. Yes, exocytosis along the shaft occurs in areas devoid of the submembrane spectrin scaffold! 7/11

[Nature Reviews Drug Discovery @NatRevDrugDisc]

New approach methodologies offer the promise of greater predictivity of safety risks of drug candidates than animal models. Find out about progress in their application in drug development in this article in the September issue
https://t.co/TgNKBze7cc
https://t.co/6qkPEiBewV

[Stephen Turner 🦋 @stephenturner.us @strnr]

Predicting gene expression from DNA sequence using deep learning models https://t.co/flQHVhGNms (read free: https://t.co/sXmAB0qfAi) 🧬🖥️🧪

[Elijah Edmondson @ElijahEdmondson]

@musk_news13 Yes

[David Sinclair @davidasinclair]

NEW STUDY: Intermittent fasting (IF) significantly alters the microbiome of mice, with reductions in the gut production of obeticholic acid, a bile acid that induces expression of gut-derived hormones, and an increase in N-acetylglycine production

Why is this interesting? 🧵

[Felipe Templo Jr. ,MD, MBA 🕊 @thejourneymate]

These Captchas are getting out of hand 🤓

[Brian Hie @BrianHie]

We trained a genomic language model on all observed evolution, which we are calling Evo 2.

The model achieves an unprecedented breadth in capabilities, enabling prediction and design tasks from molecular to genome scale and across all three domains of life.

[Smart Biology @SmartBiology3D]

From cells to DNA, we show everything to scale.
Learn more at https://t.co/rZjuFXgP1n
#biology #3D #science #EdTech

[NIH @NIH]

Last year, $9B of the $35B that the National Institutes of Health (NIH) granted for research was used for administrative overhead, what is known as “indirect costs.” Today, NIH lowered the maximum indirect cost rate research institutions can charge the government to 15%, above what many major foundations allow and much lower than the 60%+ that some institutions charge the government today. This change will save more than $4B a year effective immediately.

[Molecular Oncology @MolOncology]

🐭Robust acute myeloid leukemia engraftment in humanized scaffolds using injectable biomaterials and intravenous xenotransplantation

👉https://t.co/nAhhGGpYPo

#LYLSM #CancerModels #PDXs

[National Cancer Institute @theNCI]

New images available! NCI’s Imaging Data Commons now contains tumor and tissue images from nearly 2,000 children participating in the Molecular Characterization Initiative. Check it out! https://t.co/Kc0tRUC20d #Data4ChildhoodCancer #ChildhoodCancer #CancerResearch