Ling-shiang (Felix) Chuang, Ph.D.

Assistant Professor @MountSinai_Path & @IcahnMountSinai. #IBD Genetics #Crohn's #Innateimmunity #Zebrafish #Precisionmedicine. Comments of my own.

[Ling-shiang (Felix) Chuang, Ph.D. @Felix_Chuang240]

🧬 New on #bioRxiv: #GMCSF shapes #immune niches in #Crohn’s disease. #Singlecell spatial #transcriptomics + #zebrafish injury model show GM-CSF restrains #ILC1s, sustains #ILC3s, boosts IL-22, and limits #ulceration. #IBD https://t.co/SZlmw989Cq

[Dylan Burnette @MAG2ART]

The nuclei of the cells in the heart of a zebrafish embryo photographed through a microscope. The ventricle is on the left and the atrium is on right. #CellBiology

[Ling-shiang (Felix) Chuang, Ph.D. @Felix_Chuang240]

🎄✨ Merry Christmas! 🎅🏻 Wishing you all a day filled with love, laughter, and the warmth of cherished moments. May your hearts be as full as your plates and your spirits as bright as the twinkling lights.

[IZFS @InfoIzfs]

Apply for an exciting opportunity to visit the Kawakami Lab through the National Institute of Genetics Travel Grants. The deadline for the application is December 1, 2023 (Japanese time). Learn more about this grant and apply here: https://t.co/4eqkwIk2FA

[Zebrafish Rock! @ZebrafishRock]

Imaging the endocardium of the heart in a two-day-old zebrafish embryo. Credit to @Anjalie_Sch. #ZebrafishZunday

[Dylan Burnette @MAG2ART]

A time lapse of a cell going through cell division hand drawn by Walther Flemming while he was looking in his microscope in the 1800's. He chose to highlight the dynamics of chromosomes.

[Reto Fiolka @RetoPaul]

Our mesoscopic oblique plane microscope is online:
https://t.co/ij8xd8iibn
It enables rapid volumetric imaging of a whole zebrafish embryo with ~2.3 micron lateral resolution.

This is enabled by merging a couple of optical innovations and tricks. 1/N

[Adrian Liston @LabListon]

Where do #TissueTregs come from? The previous standard model is the "seeding and specialisation" model, where #Tregs enter from tissues, turn on a dedicated transcriptional program per #tissue, and dwell indefinitely in that tissue as specialised cells.

1/3

[IBD Mount Sinai @mountsinaiIBD]

FDA Approves Mirikizumab, a Promising Induction and Maintenance Therapy for Ulcerative Colitis. Offers new option with improved quality of life for patients with moderate-to-severely active disease https://t.co/IJoYYifqCa

[Zebrafish Rock! @ZebrafishRock]

Simultaneous tracking of 100 zebrafish larvae using open-source software. Credit to @FastTrackOrg. #ZebrafishZunday

[Zebrafish Rock! @ZebrafishRock]

Immune cells surveil the skin in an adult zebrafish explant. Credit to @errricpeterman. #ZebrafishZunday https://t.co/A0vZLhRLEY

[Ejv @ejvillablanca]

🤯

Mast cells function uncovered!

Mast cells link immune sensing to antigen-avoidance behaviour

#Nature https://t.co/eAwRbm50MC

[Ling-shiang (Felix) Chuang, Ph.D. @Felix_Chuang240]

Asian countries don't think IBD is a serious issue at the current point. But here is the prediction for 2100. #IBD #asian

[Rachel Levantovsky, MD, PhD @RLevantovsky]

Hi Twitter! I have a PhD!

I have many, many people to thank for getting me to this point, but most especially @JudyCho7 and @Felix_Chuang240 . I am so fortunate to have your mentorship and support.

[Gut Journal @Gut_BMJ]

#GUTImage from the paper by Hsu et al entitled

"NOX1 is essential for TNFα-induced intestinal epithelial ROS secretion and inhibits M cell signatures" via

https://t.co/qqRoIGFqUl

@mountsinaiIBD @shikha_nayar @Felix_Chuang240 @JudyCho7 #NOX #TNFa #IBD

[Ling-shiang (Felix) Chuang, Ph.D. @Felix_Chuang240]

Use T instead of an error bar for scientific publication!!!

[serif @serifhello]

Wait a second, these are not real error bars … the author literally just put the letter “T” above the bar graphs 😭

[Ling-shiang (Felix) Chuang, Ph.D. @Felix_Chuang240]

Our new paper is out today. Here is the link to the publication.

[IBD Mount Sinai @mountsinaiIBD]

https://t.co/qDH186H1Zr

[Ling-shiang (Felix) Chuang, Ph.D. @Felix_Chuang240]

Our new paper is out @Gut_BMJ today. ROS is crucial for maintaining epithelial stem cells. Lossing ROS results in #M cell expansion and basal #lymphoplasmacytosis.

[IBD Mount Sinai @mountsinaiIBD]

New publication @Gut_BMJ: NOX1 is essential for #TNFα-induced #intestinal #epithelial #ROS secretion and inhibits M cell signatures. Congratulations to all authors @Naiyunhsu1 @JudyCho7 @Felix_Chuang240 @shikha_nayar @mabes_nyc @TStappenbeckMD @a_azabdaftari

[Ashraf Saad, bridging Glycobiology and Oncology! @AsAshraf123321]

#glycotime
This is a substantial achievement👏
Massive congratulations 🎊 🎉 to all authors:
@nkg2d1
@Felix_Chuang240
@JeanFredericCo1
@JudyCho7
@ZhiChai_Sinai
@JoanaTo62523004
@MiriamMerad
@Salome_S_Pinho
@effiken
@petra_fra
@SiuLingTai
@gaifem_joana
@Ines_S_Alves
@Cat__Azevedo