Congratulations to SWAN Genomics, Number 8 bio, @HydgeneR and All G on securing funding from a $4.75 million BioSciences Fund, designed to help companies bring their technologies to market. 🎉
➡️ Read our story: https://t.co/4j1tgH2kWT
@arc_gov_au
Great to see this work led by @LDorstyn@CCB_Research funded by @nhmrc and many years in the making now out: Caspase-2 deficiency drives pathogenic liver polyploidy and increases age-associated hepatocellular carcinoma in mice | Science Advances https://t.co/Rbng59modd
Sun, surf and scientific talks 😎
Centre Director Ian Paulsen and COO J-L Heylen joined CoESB researchers from our @uwanews and @CurtinUni nodes for their annual Theme 2 (Synthetic Organelles) Retreat on Rottnest Island in sunny WA 🌊☀️ @TheRackhamLab@FilipovskaLab@arc_gov_au
Our story about FASTKD5 is now published at @NAR_Open. It was an amazing collaboration with @hauke_hillen and @Antonio41949078 labs.
https://t.co/Ixj5LzMWwX
FASTKD5 processes mitochondrial pre-mRNAs at non-canonical cleavage sites
This poster is a must have for labs working on #MCS! A guide through the work of so many outstanding labs (apologies if we did not cite your work). Hang it in your office or lab, it will please your eyes and inspire your mind! Kudos to the driving force Antigoni Diokmetzidou! -LS
It takes two to TANGO2!
TANGO2 binds the heat shock protein crystallin alpha B to prevent aggregation of the intermediate filament desmin and its loss models TANGO2-deficiency disorder
Many thanks to our team, collaborators and reviewers.
https://t.co/dQErSDSoUu
#metabolism
Silencing mitochondrial gene expression in living cells | Science https://t.co/wRDoCKbFzT. Wonderful that our paper is out now in Science. A big thanks to LD Cruz-Zaragoza and the team, @warscheidlab & @JakobsLab .
📢 Hunter Meeting abstract submissions close 5pm AEST today!
@ANZSCDB is proud to have joined forces with the Hunter Meeting 2025.
Please encourage your colleagues, postdocs and students to submit their abstracts today!
Link: https://t.co/58AbpP5JSA
Ready to make breakthroughs in gene editing and mitochondrial biology in sunny Western Australia?
Join our vibrant team as a Research Associate or Research Fellow. Expertise in cryo-EM, cell imaging, or mammalian genetic screens is highly desirable
https://t.co/9PipVUF3Pt
The peer-reviewed version of our paper on human tRNA 3' processing is now published in @NatureSMB. Many thanks to the reviewers for their constructive comments!
https://t.co/CckIvTOOxX
See also the very nice related work by @BMartinHallberg@no1gv: https://t.co/FOcw8tVQv0
New structural and functional analyses show that FASTKD4 supports non-canonical RNA processing and MT-ND3 mRNA stability. Thanks to all authors for their contributions and the reviewers for their kind advice!
https://t.co/0eH1tbkKDA
#RNA#mitochondria#mtDNA
Update! We outline AIVE, an AI method for volume EM data. We show the benefits of AIVE for reconstructing your FIB-SEM data, reveal some fascinating cell biology, and define intrusions as a new form of mitochondrial contact.
https://t.co/nnxj2EB3s2
Muscle mito nanotunnels 1/3🧵
Better CRISPR base editors!
More efficient nicking of the unedited DNA strand improves the ability to edit hard to reach bases.
@ACSSynBio
https://t.co/M8Sw8vW12V
Our latest preprint! Some beautiful cell biology in this one.
"Presynapses are mitophagy pit stops that prevent axon degeneration"
https://t.co/pP0JcJcXjR
Discoveries into the cell biology of of mitophagy in axons, a disease mechanism, and a potential therapeutic avenue.
1/2
Out today! We find that an epigenetic modification (6mA) to the mitochondrial genome (mtDNA) influences lifespan and the heritability of mtDNA mutations to the next generation. It implies that epigenetics determines genetic composition in future offspring.
https://t.co/U1kiQ1bjrQ