Yiling Li 李怡灵

brain lover | food addict | blind optimist | MRes @ule_lab; PhD @magdalenagoetzlab.

[Yiling Li 李怡灵 @Fionalyl]

Excited to share our latest work uncovering TGIF2 as a key transcription factor (TF) safeguarding neural stem cell (NSC) fate and regulating neurogenic priming! 🧠

🔗 https://t.co/V4lQHld77d

Here’s how we found it and why it’s important!🧵👇

[Yiling Li 李怡灵 @Fionalyl]

@NeuralGrndState Yes! That’s why we are excited to see it plays a somewhat different role in the context of neurogenesis.

[Yiling Li 李怡灵 @Fionalyl]

6/ These findings establish TGIF2 as a major regulator of NSC fate, integrating transcriptional repression with lineage priming to fine-tune neurogenesis.

Looking forward to discussions and feedback! 🔬💡

[Yiling Li 李怡灵 @Fionalyl]

Excited to share our latest work uncovering TGIF2 as a key transcription factor (TF) safeguarding neural stem cell (NSC) fate and regulating neurogenic priming! 🧠

🔗 https://t.co/V4lQHld77d

Here’s how we found it and why it’s important!🧵👇

[Yiling Li 李怡灵 @Fionalyl]

5/ Importantly, TGIF2 is not just a repressor of differentiation—it plays an active role in neurogenic priming. By keeping neurogenic priming genes at low levels to keep NSCs poised but undifferentiated, ensuring proper lineage priming.

[Helmholtz Munich | @HelmholtzMunich @HelmholtzMunich]

Curing the #Brain

Dive into the fascinating research of #cell replacement #therapy!
🎤In this #interview, Prof Magdalena Götz takes you on her scientific journey – and shares glimpse into a special experience as a #WomenInScience:
👉 https://t.co/t0vrK0GqGf

#IWD2024 #WomensDay

[Royal Academy @royalacademy]

This is ‘Emotions on the Playground' by Oscar, age 5.

Oscar says “No one would play with me on the adventure playground.”

Please can we show Oscar that he's a superstar and his painting is absolutely magical💥
#RAYoungArtists

[Florencia L Merino @flmerino_]

Very happy that our new paper from the Götz lab is out today in @ScienceMagazine! We profiled the centrosome proteome of human iPSC-derived neural stem cells and neurons and uncovered high heterogeneity with relevance for development and disease.
https://t.co/hAfCTRDpwI

[Laurent Nguyen @neuroliege]

🎉 Happy to share our latest work! Congratulations for the fantastic achievement @fanny_lepiemme ⁦@CarlaGSilva1⁩ ⁦@miriam_jt⁩ ⁦@StouffletJ⁩ with help from ⁦@MazzuGabi⁩ https://t.co/vm8llSDeWx

[Oscar Wilkins @OscarWilkins16]

Great opportunity to join our team (@FrattaLab) working on an innovative new gene therapy for ALS/FTD. A mix of novel computational (incl. new machine-learning approaches), molecular & cellular biology, all with a real therapeutic aim. Get involved! Link: https://t.co/AooShrypK8

[scverse @scverse_team]

We are very excited to announce scverse (https://t.co/B4lDGfWDPQ), a new consortium around the core Python packages for single-cell omics data analysis. scverse is a cross-lab effort to ensure the longevity and interoperability of the single-cell analysis ecosystem in Python.

[Yiling Li 李怡灵 @Fionalyl]

@ilFerrinho Best of luck and success!

[Rahul Satija @satijalab]

Three recent manuscripts reporting multimodal (RNA+protein) extensions of spatial transcriptomics!

1. SM-omics (@mssanjavickovic) : https://t.co/V2Ri9SZH5e

2. SPOTS (@landau_lab): https://t.co/XMFaxpMMQ7

3. Spatial-CITE-seq (@RongFan8): https://t.co/q2uGL5ykNY

[Rowan Hooper ローワン フーパー @rowhoop]

This week’s podcast has a late contender for my story of the year: human brain cells, wired into the Matrix, playing Pong 🤯 (by @mjflepage)

https://t.co/xCXtNKNJAQ

[Yiling Li 李怡灵 @Fionalyl]

The list of speakers is incredible 🤯😶‍🌫️

[Sergiu P. Pasca @Sergiu_P_Pasca]

I hoped we could have an in person, 3rd CSHL 𝐃𝐞𝐯𝐞𝐥𝐨𝐩𝐦𝐞𝐧𝐭 𝐚𝐧𝐝 𝟑𝐃 𝐌𝐨𝐝𝐞𝐥𝐢𝐧𝐠 𝐨𝐟 𝐭𝐡𝐞 𝐇𝐮𝐦𝐚𝐧 𝐁𝐫𝐚𝐢𝐧. Guo-li Ming & I decided to move it to 2022. No doubt it will be best so far! See speakers👇
#organoids #assembloids #disease
https://t.co/4bC2jg2Pfp

[Martina Hallegger @martinahallegg1]

Enormously proud of the result of this amazing collaboration with @am_chakrabarti, @fcylee, @luslab, @ShorterLab, @Nicolas_Fawzi and @PataniLab on how TDP-43 condensation specifies RNA binding and regulation now published in @CellCellPress https://t.co/VI2fTfLTTx

[Arlotta Lab @ArlottaLab]

We are proud to share our paper with a comprehensive single cell RNA-seq, ATAC-seq and spatial atlas of the developing mouse neocortex, led by @DanielaJDiBella from the @ArlottaLab and @ehshabibi from Aviv Regev’s lab. https://t.co/LfqcEBqbYR