Gabriele Simontacchi

Radiation Oncologist in Florence, Italy.

[Chad Tang, MD @ChadTangMD]

Extremely excited to share our latest article published @TheLancetOncol a few hours ago: https://t.co/du9hQOzHv7.

The WOLVERINE individual patient meta-analysis was an international collaboration and part of X-MET collaboration. Goal was to evaluate MDT in oligomet prostate ca.

[Riccardo Noury @RiccardoNoury]

“Il 2025 sarà ricordato come l’anno in cui abbiamo accettato che le guerre potessero essere governate da regole diverse, applicate a seconda del contesto, degli alleati, della geografia morale di chi guarda”. @mannocchia
https://t.co/NoX1PxtVeN

[Giulio Francolini @GiulioFrancoli1]

📢 Re-irradiation for prostate cancer relapse after prior radiotherapy is safe,and effective. A study on behalf of Italian association of radiotherapy and clinical oncology (AIRO)
🔬 54-month fup
✅Low rates of severe toxicity
📈 BRFS: 34 months
🔗 https://t.co/Nep1qVRI3G

[Jonas Willmann, MD @jonas_willmann]

❓ESTRO & EORTC proposed a classification to standardize reirradiation. But does it predict outcomes or toxicity?

🫁☢️ We applied the classification in thoracic reirradiation for NSCLC.

Here’s what we found.
🧵

[Matteo Villa @emmevilla]

🇵🇸🇮🇱 Comunque la pensiate sul conflitto, lasciare un'intera popolazione assediata senza cibo e aiuti umanitari è un crimine di guerra.
A mio parere, uno dei peggiori.

Dopo il collasso del cessate il fuoco, da DUE mesi non entra più alcun aiuto nella Striscia.

Terribile.

[Gabriele Simontacchi @GabSimontacchi]

@isteddos @Icro_Meattini 😂 Definitiva!

[Matthias Guckenberger @Mat_Guc]

Remember the misleading press reports about "brutal" #radonc after PROSPECT ?

This is what modern radiotherapy can achieve for elderly breast cancer patients!
👉 "Endocrine Tx was associated with a greater reduction in HRQOL compared with RT at 24 mo"
👉 oncological data awaited

[The Lancet Oncology @TheLancetOncol]

Presented at #SABCS24:

Interim results from the EUROPA trial:

Single-modality #endocrinetherapy vs #radiotherapy after breast-conserving surgery in women aged 70 years and older with luminal A-like early #breastcancer
https://t.co/ay6evWBQBG

[Matthias Guckenberger @Mat_Guc]

Must read clinical trials in the field of #SBRT 2024

Please complement the list, to allow us staying up-to-date !

[JeeSuk Chang @changjeesuk1]

(1/4) Check out our latest editorial in @RadiotherapyOn1 Green J, where we dive into the nuances of oligomets!

Link: https://t.co/N6b7UlzmOC

In the clinic, we often describe tumors as indolent vs. rapidly progressing. But we still lack a solid metric to quantify this.

[Gabriele Simontacchi @GabSimontacchi]

@AshleyGWinter Or...
Husband: why do you always have to carry such a large and heavy bag?

Later:
-eats the snacks I packed
-drinks my water bottle
-uses my cell phone charger
-uses my umbrella
-asks me for a tissue
-puts all the keys inside the bag
-etc...

[UroToday.com @urotoday]

Apalutamide and SBRT for low-burden, metastatic, hormone-sensitive #ProstateCancer #PERSIAN. Presentation by @GiulioFrancoli1 @AOUCareggi. #GU24 written coverage by @RKSayyid @UofT > https://t.co/u888XAKtbZ @ASCO

[Gabriele Simontacchi @GabSimontacchi]

@adapthyun @MikeChuongMD @PercyLeeMD @lauren_henke @atomsmasher137 @APrice_BeamOn @gdhugo @SBRT_CR @jmmrad @drjamesgood @samsonpp @toddscarbrough And let's remember that half (in some cases more...) of a pharma company budget goes in... marketing!

How could we calculate the fair reimbursement for RT?

[Gabriele Simontacchi @GabSimontacchi]

@adapthyun @MikeChuongMD @PercyLeeMD @lauren_henke @atomsmasher137 @APrice_BeamOn @gdhugo @SBRT_CR @jmmrad @drjamesgood @samsonpp Just an example, I remember this by @toddscarbrough (not to talk about CAR T...)

[Gabriele Simontacchi @GabSimontacchi]

@toddscarbrough @gerryhanna @_ShankarSiva @MP_MacManus @cbcrockett87 @JolyneOHare The % is relative to all N relapses, we miss total number of pts...could be 1-2% absolute or less? Anyway seems high also contralat hilum, about 1/5 of ipsilat hilum in limited stage pts

[Gabriele Simontacchi @GabSimontacchi]

@ScaltritiLab Aggiungerei che con un trattamento radioterapico stereotassico ad intento ablativo, caratterizzato da una tossicità sostanzialmente trascurabile, nella maggior parte dei casi potrebbe evitarsi il trattamento farmacologico, con i suoi costi e la sua tossicità.

[Giulio Francolini @GiulioFrancoli1]

Quality of Life After radical treatment for MIBc (cistectomy +/-neobladder vs bladder sparing approach): a systematic review #ASCOGU23,@dicataldovanes1,@Atem84,@isteddos,@GabSimontacchi,@Icro_Meattini
https://t.co/8HbuzHweve

[Icro Meattini @Icro_Meattini]

A true honor having accepted this challenge among great Friends and Colleagues! @ESTRO_RT #radonc #medphys #OncoAlert #breastcancer @OncoAlert @ASTRO_org @UNI_FIRENZE @AOUCareggi