Published today in @Nature: A new Fred Hutch study using a first-in-kind rapid autopsy program shows details of metastatic bladder cancer subtypes; could improve diagnosis and future treatment. https://t.co/mQIo8YjE9r
@pushpa_itagi@HsiehLab@GavinHa@DrOmarMian
This work was led by @GavinHa , @HsiehLab, Ming Lam, and @DrOmarMian, involving 5-years of tissue collection followed by 5-years of analysis. The UW/Fred Hutch Rapid Autopsy Program was founded by Drs. @JLWrightMD, Bruce Montgomery, Ming Lam, Funda Vakar-Lopez, @HsiehLab
Ever wonder how heterogeneity defines bladder cancer subtypes?
Ha and Hsieh Lab postdoctoral fellows @pushpa_itagi and Samantha Schuster @fredhutch did, leading to a deep study of bladder cancer clonality, evolution, and heterogeneity published @Nature
https://t.co/gSXSWXJ2ST
In a step toward a #liquidbiopsy for small cell #lungcancer, a Fred Hutch team led @DMacPhersonLab and @GavinHa have developed an approach that can distinguish several #SCLC subtypes from blood samples. https://t.co/IeZVRe6nmp
So excited to share our work on tumor genomes of African ancestry in common cancers. We report several actionable associations, including a novel ancestry-smoking interaction impacts TP53 rate. More discoveries to come if we improve diversity in genomics! https://t.co/hfhO23PNmn
Congrats to Robert Patton for being awarded the @PCF_Science 2023 Young Investigator Award & achieving the top scoring application! Honored to be his co-mentor with PeteNelson. #PCFRetreat23
The #MahanFellowship supports young scientists in the early stages of their careers. We offer fellows a 21-month stipend as they pursue their proposed research project, alongside a mentor in one of our Herbold Computational Biologist labs. Apply today: https://t.co/X9IHSgIkJ6
Have you ever wondered if 3’UTR point mutations found in cancer patients matter? We’re excited to share our new publication out today @CellReports, where we’ve defined how prostate tumor 3’UTR mutations affect molecular & cellular oncogenicity. https://t.co/MhKM0S2uZW 1/n
Excited to share our recent work on KaryoCreate, a new method to engineer chromosome-specific gains and losses in human cells with @SteSantaguida and @GiuntaLab https://t.co/Eg7aEDAB7u Check out also recent similar and complementary work by @LensSusanne and @McClellandLab!
Attending the Major Symposium at #AACR23 about Liquid Biopsy? See the related paper published in @CD_AACR: Nucleosome Patterns in Circulating Tumor DNA Reveal Transcriptional Regulation of Advanced #ProstateCancer Phenotypes by @GavinHa and @Navonilde
https://t.co/rLrNZ00kcr
Fred Hutch is recruiting a faculty member for our #prostatecancer research program. Focus areas include primary prevention, etiology, genetics/genomics, epigenetics, tumor microenvironment, metastasis, development of novel therapeutics and more. Apply: https://t.co/shBLW17Ji6
In the March issue of Cancer Discovery—
Nucleosome Patterns in Circulating Tumor DNA Reveal Transcriptional Regulation of Advanced #ProstateCancer Phenotypes, by @Navonilde, Robert Patton, Peter Nelson, @GavinHa et al
https://t.co/8NvLtDOYlI
@fredhutch#LiquidBiopsy#cfDNA#ctDNA
Faculty position opening! Assistant or associate faculty professor in the @fredhutch Prostate Cancer Research Program! Broad research expertise considered (e.g., prevention, genetics/genomics, therapeutics): https://t.co/L4lAWPjz9X
@NewPI_Slack@FuturePI_Slack#prostatecancer