Helfrid Hochegger

Cell biologist interested in cell cycle control mechanisms

[Rhys Morgan @RhysMorganLab]

Pleased to share 15 amazing international and interdisciplinary PhD projects now available through the FlexCAT MSCA-DN targeting oncogenic β-catenin.

Includes our own project (DC14) hosted here at @SussexUni @BiochemBiomedUS

Deadline 31/10/26 via:

https://t.co/6LrAyJFNrA

[Helfrid Hochegger @HHochegger]

@Sachin_mitosis @emboreports This is pretty cool! Congrats

[Helfrid Hochegger @HHochegger]

@NatureComms Fantastic team effort led by Robert Zach.
Special thanks to @CR_UK and @wellcometrust for support and the many other authors to make this collaboration possible 🙏. Happy to discuss the work - comments and questions welcome!

[Helfrid Hochegger @HHochegger]

Excited to share our new @NatureComms paper! We developed C-604, a selective inhibitor of Greatwall kinase, and discovered that cancer cells' sensitivity to it depends on a simple ratio: B55α/Greatwall expression levels.
#CellBiology #CancerResearch
https://t.co/DuwPAJ2gfX

[NealeLab /labneale.bsky.social @LabNeale]

Happy 21st Birthday to the GDSC! Celebrating the next two days with colleagues and alumni 🎉
@GDSC_Sussex

[Yuki Hatoyama @yh_biol]

Our new paper has just been published!!
We made a double-degron system combining AID2 and BromoTag to enhance the power of degron. Using this, we were able to strongly inhibit the initiation of DNA replication in human cells, ultimately inducing mitosis without DNA duplication.

[Adrian Saurin @AdeSaurin]

Excited to reveal our new chemical-genetic system to inhibit PP2A-B56 phosphatase. We use this to characterise its substrates and roles during mitosis. This is a simple yet powerful approach to inhibit any enzyme/protein relying on SLiM-based interactions
https://t.co/1poQ2FYsLv

[Joseph Burclaff @JosephBurclaff]

The first paper from my research group is published! We engineer the first cell cycle reporters in primary human intestinal monolayers, design a collagen press for optimal imaging, and compile a computational pathway for image analysis. https://t.co/inMgjYKfSt

[Will Kinney @WKCosmo]

This is possibly my favorite Calvin & Hobbes.

[Diorge Souza @diorge_souza]

We're thrilled to share our new preprint: "Evolutionarily Conserved Principles of ESCRT-III-Mediated Membrane Remodeling Revealed by a Two-Subunit Asgard Archaeal System."

https://t.co/1SboXsSj81

[Max Perutz Labs Vienna @MaxPerutzLabs]

2️⃣ new publications from Joao Matos and his team with are out now! 🤩 In @CellPressNews the team introduces a new method for investigating filaments. In @Dev_Cell the team characterizes the proteome during meiosis 🧬 ➡️ https://t.co/OVL4HwjHwf and https://t.co/OXmiuViuUu

[Guido van Rossum @gvanrossum]

Exactly.

[James Lucas @JamesLucasIT]

Thread of photographers who patiently waited to capture the shot of a lifetime 🧵

1. Leonardo Sens (3 years)

[Benoit Bruneau @benoitbruneau]

What the hell Jeremy? What. The. Actual. Hell?!? This broke my brain @ReiterLab. Seriously though, mind blowing. https://t.co/dW71ul1JjJ

[Sophie Dumont @DumontLab]

Excited to share our work @JCellBiol! We find that chromosome size-dependent spindle forces impair mammalian mitotic error correction of long chromosomes. Congrats to graduate student
@megan_chong who led this work! With Miquel
@RosasSalvans @VannaTran5
https://t.co/mSBj0Rs25G

[Robertus de Bruin @DeRobertus]

The Cell Cycle Club meeting is back, in-person @TheCrick London, June 4 & for global participation live streamed for virtual attendees!

PRESENT YOUR WORK?
SUBMIT AN ABSTRACT (deadline 17 May)

ATTEND THE MEETING
Register for this FREE @Abcam event now!

https://t.co/FYDQ8zbKhB

[Simon Mitchell @SiFTW]

So proud to announce that we’ve launched the new Sussex Cancer Research Centre spanning @BSMSMedSchool @SussexUni @uniofbrighton, @UHSx_Research, @ESHTNHS and NHS trusts across Sussex.
Read more, come to the launch event, and follow us:
https://t.co/hM9isf2DFR
@Sussex_Cancer

[PRX Life @PRX_Life]

This PRX Life paper debuts DisNet2D, a deep #NeuralNetwork for image analysis. The method merges tracking and segmentation to achieve low error rate, allowing advanced image analysis of densely-packed cells.

📝 https://t.co/87H3Z01pct

[Ivor Simpson @DrIvorSimpson]

I'm really excited to announce that our brand new MRes in Advanced Artificial Intelligence is now available on the @SussexUni website https://t.co/XnrUkZhN6k! This course offers research focused training in how to be an effective and responsible AI scientist or engineer.

[Miguel Godinho Ferreira @MGodinhoFerr]

On our paper: Interesting Insight into the Relationship Between TP53, Telomerase, and Telomere Length – Fight Aging! https://t.co/Z1OOKhVDFc