Please read and critique our new paper on the genetic determinants of human kidney function @NatureGenet:
https://t.co/MxyiCzKRfN
We combined GWAS with CNN and CRISPRi to go from loci to target genes. This roadmap may be useful to others uncovering genes underlying human traits.
Only two more weeks to submit abstracts for the FASEB Cilia and Centrosomes. Abstract submission deadline is June 8. Submit an abstract and come share your exciting science with the community!
https://t.co/xMS1X3QNzE
Please come join me in Washington, DC August 2-6th for the FASEB SRC on Cilia and Centrosomes meeting! Over 40 talks will be selected from abstracts. We are also excited to launch our first North American Ciliopathy Summit, held at the same venue on Aug 2. https://t.co/qvm1I0NosK
Our new paper led by @XiaoxinChen2024 is out @PNASNews! https://t.co/6drZWimYAt
We built a tissue atlas of ~2K transcription regulators ➔ identified Tox3 as a long-sought Atoh1 amplifer in cerebellar development, tumorigenesis & evolution. 1/10
📢 We're recruiting postdocs!
Thrilled to share our new study in collaboration with @TerenceRyan_PhD. We find that intramuscular adipose tissue (IMAT) directly impairs limb muscle function in PAD/CLTI and that preventing IMAT formation improves functional outcomes in experimental PAD. https://t.co/O7Tubo7KJM
Check out this article in @ScienceMagazine featuring our Vilcek Prizewinners: Karolin Luger, @TakashiAkeraLab, @AashishManglik, and @BernaSozen_ !👏
These immigrant scientists are shaping the future of medicine, from uncovering the hidden mechanisms of our cells to advancing treatments for disease. 🔬✨
Read more about their discoveries: https://t.co/MAYxNs5TZo
Polycystic kidney disease is the most common monogenic cause of kidney failure and affects over 10 million individuals. We've known most PKD is caused by mutations in PKD1 for over 30 years. But how PKD1 prevents disease has remained mysterious, limiting effective therapy.
Janelia is hiring Group Leaders! Work alongside superstars like Luke Lavis, @JiefuBiol, @mengwang939, @JLS_Lab, @ERSchreiter. If you have ideas that are perhaps too ambitious or crazy for a traditional academic setting, that is exactly who they are looking for.
Tool-builders at all career stages with original, transformative ideas for experimental approaches in imaging, molecular engineering, protein chemistry, mass spectrometry, and methods that don’t yet exist: Apply by Feb. 3, 2026: https://t.co/WcEOWPoxw5
Excited to have my first senior author publication out in the world! An awesome collab between myself in the @ReiterLab and the Berbari lab at IU. We found primary cilia are necessary for postnatal pituitary development. 1/n.
https://t.co/9JGQtPuu0p
In their Cell Science at a Glance article, Dagmar Wachten & Søren Tvorup Christensen @t_soren explore the primary cilium as a master regulator of cellular communication that integrates diverse signalling pathways in development & homeostasis.
#JCSciliaSI
https://t.co/JAd7Xl6vxW
Good morning, Bay! I’m up early to head out to University of Florida @uflorida and Daniel Kopinke @KopinkeLab. I hope to see you at the Dept of Pharmacology seminar Wednesday!
I am excited to share our preprint of CiliaTrack, a novel machine learning approach to PCD diagnosis. Proud of Nicolas Hadas, a talented PhD candidate in my lab, for developing the code and his amazing work on this project.
https://t.co/fCwO6xcUcs
Check out our latest manuscript where we generate a cross model single cell and spatial atlas of mouse PKD!
A cross model spatial and single-cell atlas reveals the conserved involvement of osteopontin in polycystic kidney disease | bioRxiv https://t.co/ICBC4SXIXJ
More than 12 million people globally are impacted by ADPKD, and it still lacks disease-modifying therapies. Renasant Bio is on a mission to advance next-generation treatments for ADPKD through the development of small molecule correctors and potentiators. https://t.co/TMsUjd0v8w
Thank you to all PKD community members who have advocated over the years, and all who are standing up for the PKD community during this important time. Together, we can #EndPKD.
Want to add your voice? Join our Advocacy Champions Network: https://t.co/AnB9fEaDE1
Whitehead Institute Founding Member Rudolf Jaenisch has received the 2025 Ogawa-Yamanaka Stem Cell Prize, which recognizes his seminal role in establishing and advancing the field of induced pluripotent stem cells (iPSCs). https://t.co/inhUyjIigA @GladstoneInst