Taner

Asst. Prof.

[Molecular Cell @MolecularCell]

Programming biological behavior with AI-guided de novo protein design. www.​cell.​com/molecular-cell/fulltext/S1097-2765(26)00615-5

[htw @heniek_htw]

GABA regulates neuronal, immune & gut-brain signaling in preclinical models
LAB synthesize GABA via GAD; strain-specific GABA-T route needs validation
GABA-enriched foods may improve flavor and offer health benefits
Genetic editing, co-culture & stimulation may boost GABA yield

[David Sinclair @davidasinclair]

Could gut bacteria from long-lived people be used to treat Alzheimer's (AD) & aging? NMN-producing bacteria from healthy older adults were tested in a worm model of AD. Lifespan was extended & behavioral deficits were less 🪱💪😋 What if we ate them?
https://t.co/okg2MXF6IW

[Cell Host & Microbe @cellhostmicrobe]

Akkermansia protects against endometritis

A.muciniphila protects against endometritis by driving tyrosol production, which reaches uterus & suppresses inflammation. Work reveals metabolite-mediated gut-uterus axis linking microbiota to reproductive health
https://t.co/ncSQPi0lyj

[Cell @CellCellPress]

In the latest issue! Resident tissue macrophages transfer selenium transporter protein to protect pancreatic cancer from ferroptosis dlvr.​it/TVzRrM

[David Sinclair @davidasinclair]

FOXO protein regulates genes & extends lifespan in simple organisms. New review discusses how it organizes the epigenome in response to adversity signals: lower ATP, NAD+ & S-adenosyl-methionine (SAM) ⚡️
https://t.co/yZ7xOdiNkq

[Eric Topol @EricTopol]

We are all mosaics with our cells accumulating somatic mutations as we age. Now that is getting fully comprehensively quantified @CellCellPress
https://t.co/o0Vh75u5iU

[Eric Topol @EricTopol]

Spotlighting the macrophage cells in our blood and tissue, their role in diseases, and targeted interventions
https://t.co/dmcdQJCrnj @ImmunityCP

[Samuel Hume @DrSamuelBHume]

This is a beautiful way to visualize the pathophysiology.

B cells at different stages of differentiation occupy different compartments, express different surface markers, and drive different pathologies.

Based on this biology, it'd make sense that (for example) lupus would respond best to anti-CD19 therapies, while Sjögren’s would respond best to anti-BCMA -- though how that shakes out in trials isn't fully known.

[Dr. Thomas Ichim @exosome]

Who needs #ozempic when you have #anktiva ??

Peer reviewed paper showing IL-15 promotes weight loss independent of lymphocytes....

https://t.co/n7CgvKpzq3

[Nature Medicine @NatureMedicine]

Utilizing longitudinal data from 52,236 patients with cancer, this study created a multimodal atlas of cancer cachexia, demonstrating that weight-loss episodes are linked to systemic serologic signatures and specific tumor genotypes. dlvr.​it/TVxNP3

[Cell Host & Microbe @cellhostmicrobe]

Bacteria promote kidney stones

C. glucuronolyticum-like bacteria enriched in urine of calcium oxalate stone patients & promote CaOx crystallization via hippuric acid degradation & biofilm formation. Hippuric acid prevents bacteria-driven crystallization
https://t.co/1k8s6GMfq8

[Dr. Thomas Ichim @exosome]

I want to learn more about baking soda and cancer....

https://t.co/8WK6GzeAzV

[Dr. Eric Berg DC @dr_ericberg]

Clogged arteries are not just a cholesterol problem.

Inflammation, insulin resistance, and damage to the arterial lining can all drive plaque buildup.

Check the daily food and lab markers that matter most for prevention.

https://t.co/ZVbJsuIfVV

Dr. Eric Berg, DC, not MD; information only

[Eric Topol @EricTopol]

In 100% agreement
Exercise should be a prescribed
New @JACCJournals @ACCinTouch scientific statement
https://t.co/q4xiEvEUKC

[Mike Lustgarten, PhD @mike_lustgarten]

Age-associated Autoimmunity Driven by T cell Immunosenescence https://t.co/kNuOny0yXd

[Dr. Eric Berg DC @dr_ericberg]

Potential heart problems and top natural heart remedies:

1. A clot
Top remedies:
• Nattokinase
• Garlic

2. Plaque
Top remedies:
• Tocotrienols
• Vitamin K2
• Vitamin C

3. Cholesterol
Top remedies:
• Niacin
• TUDCA

4. Angina
Top remedies:
• Tocotrienols
• CoQ10

5. High blood pressure
Top remedies:
• Potassium
• Vitamin D

6. Homocysteine
Top remedy:
• B vitamins (nutritional yeast)

7. Enlarged heart
Top remedies:
• Vitamin B12
• TUDCA
*Make sure your iron isn’t too high

8. Murmur
Top remedy:
• B vitamins (nutritional yeast)

9. High pulse rate
Top remedy:
• Potassium

10. Arrhythmias
Top remedies:
• Potassium
• Magnesium
• TUDCA

Dr. Eric Berg, DC, not MD; information only

[Cell Press @CellPressNews]

"Early-life high-fat diet accelerates the developmental trajectory of vagal satiation signaling and predisposes females to overconsumption."

Learn more in Cell Reports: https://t.co/Ju9vRLEJiE

Anna Kamitakahara & colleagues
@CellReports

[ShorterLab @ShorterLab]

Memory stays strong in old age when this brain enzyme is active https://t.co/cNmSVJnmZw

[Aging Science News @AgingBiology]

Cellular senescence: six decades of discovery and reinvention
https://t.co/hUnub2bNTs