Excited to share our new study @ScienceMagazine by the fantastic Raphael Mattiuz and @jboumelha@SinaiImmunol showing how DC build and sustain tertiary lymphoid structures in cancer. A major step toward enhancing anti-tumor immunity (1/2) https://t.co/H8awCDz0HM
Pleased to share our latest work from @MiriamMerad lab @SinaiImmunol, where we try to address the Q: Do tumors alter the epigenetic state of myeloid progenitors in marrow, and are certain aspects of immunosuppressive mono-macrophage fate sealed before they enter the tumor?🧵
Excited to share our work with @HalaszLaszlo, now on bioRxiv, on how the systemic effect of a tumor can remodel the epigenomic landscape in peripheral monocytes and shape how they respond to the tumor microenvironment.
https://t.co/nFtLKX0ODo
Interested in single cell genomics but need help getting started? Check out my lab's Single Cell Genomics Day on March 4. Talks will feature recent exciting computational and experimental advances and will be livestreamed at https://t.co/zG98gkckMU. Please RT/spread the word!
In @JExpMed, @anpatsalos, @HalaszLaszlo, and colleagues from the @LaszloNagyLab discover that myeloid GDF-15 is required for proper muscle regeneration following acute injury and is produced by a unique growth factor-expressing #macrophage subpopulation. https://t.co/AN458eRTlR
.@anpatsalos, @HalaszLaszlo, and colleagues from the @LaszloNagyLab discover that myeloid GDF-15 is required for proper muscle regeneration following acute injury and is produced by a unique growth factor-expressing #macrophage subpopulation. https://t.co/kbzGTAH6AN
#StemCells
Required reading for anyone who uses Hi-C in their work. It is humbling to realize what we have been missing by using Hi-C datasets with the standard ca. 500 million contacts, specially when calling compartments. https://t.co/S8qvakQW1D
ScPhere (w/ Aviv Regev @broadinstitute@MITBiology@kochinstitute @HHMINEWS, now @genentech) was published @NatureComms https://t.co/JfgGVl9Hal. ScPhere (pronounced “sphere”, Aviv coined this word & pronunciation) embeds cells into non-Euclidean spaces and addresses batch effects
After almost 7 years working in the field of macrophage-mediated muscle regeneration, I am happy to share our recent (and my first!!!) invited review on the concept of Regenerative Inflammation...!! 😀🥳
https://t.co/VyLCtnyHwU
New Research: Unorthodox Transcriptional Mechanisms of Lipid-Sensing Nuclear Receptors in Macrophages: Are We Opening a New Chapter?: Work over the past 30 years has shown that lipid-activated nuclear receptors form a bridge between… https://t.co/fWOQk2Abno #Endocrinology#Endo
@LaszloNagyLab has a new review out in @FrontEndocrinol from @ZCzimmerer and @HalaszLaszlo, where we give an overview for the recent advances in the understanding of the lipid-activated nuclear receptor-mediated non-classical actions in macrophages.