Hongtao Yu Lab

Our lab studies the cellular mechanisms that govern chromosome inheritance and integrity.

[Choi Lab @EunheeChoi12]

Happy to share our new paper @NatureComms showing that insulin-independent insulin receptor (IR) activation mechanism by peptide agonist which activate non-functional IR mutants that cause the insulin resistance syndromes.https://t.co/JZy7pafpDV

[Choi Lab @EunheeChoi12]

STAG2 promotes the myelination transcriptional program in oligodendrocytes https://t.co/h7S6VT5EIl

Beautiful work by @Ningyan8 and @Hongtao_Yu_Lab! Congratulation Ningyan!

[Hongtao Yu Lab @Hongtao_Yu_Lab]

@JunminPengLab @eLife Thanks!

[Hongtao Yu Lab @Hongtao_Yu_Lab]

Our cryo-EM structure of VASH1-SVBP bound to microtubules comes out @eLife. Great collaboration with Luke Rice lab!

https://t.co/D3b4UdcQeO

[Hongtao Yu Lab @Hongtao_Yu_Lab]

@yu_yonghao Thanks!

[Science Magazine @ScienceMagazine]

A structure provides insight into how cohesin, a protein that mediates sister chromatid cohesion, entraps #DNA. Read the research in Science: ($) https://t.co/3tbr6919kd

[Hongtao Yu Lab @Hongtao_Yu_Lab]

@rwkhms Thanks, Randy!

[Hongtao Yu Lab @Hongtao_Yu_Lab]

Our cryo-EM structure reveals how cohesin-NIPBL entraps DNA. Fantastic collaboration with @bxc82 lab.

https://t.co/nWHiygKWvU

[Zhubing Shi @ZhubingShi]

Excited to share our paper online ⁦@ScienceMagazine⁩ reporting the cryoEM structure of DNA-bound human cohesin-NIPBL complex. Great collaboration between ⁦@Hongtao_Yu_Lab⁩ and ⁦@bxc82⁩ lab.
Many thanks to editors’ and reviewers’ efforts! https://t.co/qpvy4vtdqF

[Hongtao Yu Lab @Hongtao_Yu_Lab]

@Marston_lab @bxc82 Thanks, Adele!

[Hongtao Yu Lab @Hongtao_Yu_Lab]

@IlyaFinkelstein @bxc82 Thanks, Ilya!😊

[Hongtao Yu Lab @Hongtao_Yu_Lab]

Congrats, Eunhee! 👏👏👏

[Choi Lab @EunheeChoi12]

Dr. Eunhee Choi Selected as Recipient of Alice Bohmfalk Charitable Trust Award https://t.co/cBIeTv5JDW

[Hongtao Yu Lab @Hongtao_Yu_Lab]

Say farewell to @EunheeChoi12 ! We will miss you!

[Ilya Finkelstein @IlyaFinkelstein]

Exciting to see our work in press! A phenomenal collaboration with @Hongtao_Yu_Lab
Researchers Solve Decades-Old DNA Mystery https://t.co/2S2MPBsa27

[Choi Lab @EunheeChoi12]

Read our latest #research on [#Insulin-like growth factor receptor], published with @SpringerNature in @NatureComms

[Structural basis of the activation of type 1 insulin-like growth factor receptor]

Read here: https://t.co/U7HvtKfDaM

[Elphege Nora Lab at UCSF @ElphegeNoraLab]

Mooaar!

"the loop-extruding complexes most frequently contained two cohesin molecules"

https://t.co/yaalwTjyqO
By @Hongtao_Yu_Lab @IlyaFinkelstein @ZhubingShi et al.
Really fascinating

1 or 2 cohesins for bidirectional extrusion?🤔
Different assays > different conclusions? 🤔

[Zhubing Shi @ZhubingShi]

Our cohesin loop extrusion paper is online @sciencemagazine. Great collaboration with @IlyaFinkelstein lab at UT Austin. ⁦@Hongtao_Yu_Lab⁩ https://t.co/xJnaFBh5Z8

[EMDB - EMPIAR @EBI @EMDB_EMPIAR]

Putting a🎀on it! Released today @EMDB_EMPIAR & @PDBeurope, & published @eLife, the 3.2 Å #cryoEM structure of full-length #InsulinReceptor bound to 4 #Insulins by Emiko Uchikawa, Eunhee Choi, Guijun Shang, @Hongtao_Yu_Lab & Xiao-chen Bai from @UTSWNews. (1/2)

[Hongtao Yu Lab @Hongtao_Yu_Lab]

Happy Birthday, Dr. Yu!