Zhubing Shi

Assistant Professor at Westlake University. Interested in chromosome biology and macromolecular assembly.

[Zhubing Shi @ZhubingShi]

@ZhejianJ @RapoportLab @jrengen @GygiLab @DamonRunyon Congrats!

[Nature Reviews Molecular Cell Biology @NatRevMCB]

On July cover
#Review by Iain Davidson and Jan-Michael Peters @IMPvienna on SMC complexes in genome folding

#ChromatinFolding #3Dgenome

https://t.co/aINMIYsxaz

[Zhubing Shi @ZhubingShi]

@YuanHe_NWU @SiyuChen91 Congrats! Another beautiful structure. 👍👍

[Zhubing Shi @ZhubingShi]

@ElphegeNoraLab @NatureComms Yes, the similar motif as in WAPL and sororin.

[TIME @TIME]

This map shows how America voted in every election since 1824 https://t.co/qnmUJc9oi6

[The Nobel Prize @NobelPrize]

BREAKING NEWS:
The 2020 #NobelPrize in Chemistry has been awarded to Emmanuelle Charpentier and Jennifer A. Doudna “for the development of a method for genome editing.”

[Zhubing Shi @ZhubingShi]

A similar DNA trapping state of yeast cohesin-Scc2 complex as in our human cohesin-NIPBL structure.

[cryoEM Papers @cryoEM_Papers]

A Structure-Based Mechanism for DNA Entry into the Cohesin Ring https://t.co/8KDN5vX98H

[Zhubing Shi @ZhubingShi]

@IlyaFinkelstein @isabel_stroh Excellent work! Congrats!

[MRC Laboratory of Medical Sciences (LMS) @MRC_LMS]

🎉🎉NEW RESEARCH🎉🎉
@mikhailspivakov & colleagues in our Functional Gene Control group have asked whether cohesin really is the driving force behind bringing enhancers and their target genes into close proximity.

Find out more in this video & link:
https://t.co/Nt7707iJQz

[Zhubing Shi @ZhubingShi]

Christian Haering and Jan Lowe labs reported multiple conformations of yeast condensin in apo and ATP-bound states. https://t.co/QW04di8JUz

[cryoEM Papers @cryoEM_Papers]

Cryo-EM structures of holo condensin reveal a subunit flip-flop mechanism https://t.co/bkysoxGJs4

[Science Magazine @ScienceMagazine]

A structure provides insight into how cohesin, a protein that mediates sister chromatid cohesion, entraps #DNA. Read the research in Science: ($) https://t.co/3tbr6919kd

[Cees Dekker @cees_dekker]

Exciting finding:
The cohesin SMC complex is not only a DNA-loop extruder but can also induce phase separation!

Now at @biorxivpreprint: https://t.co/7uWBzkJeE7

Check out this major surprise! Great work of postdoc @JeKyungRyu1 at #CDlab together with #Uhlmann & @Dmichiel1 labs.

[Zhubing Shi @ZhubingShi]

New paper from Kim Nasmyth lab shows Scc2 and Scc3 have different roles in DNA entrapment by cohesin. https://t.co/QHC4u6s5Ny

[Zhubing Shi @ZhubingShi]

@IlyaFinkelstein @McLellan_Lab Great work. It’s very helpful for the world to overcome this pandemic. Congrats!

[International Space Station @Space_Station]

The @SpaceX #CrewDragon launched at 3:22pm EST today with @Astro_Doug & @AstroBehnken onboard. It will dock to the space station Sunday about 10:29am. #LaunchAmerica https://t.co/pfTdcoVqiN

[Zhubing Shi @ZhubingShi]

@mahipalganji Thanks!

[Zhubing Shi @ZhubingShi]

Excited to share our paper online ⁦@ScienceMagazine⁩ reporting the cryoEM structure of DNA-bound human cohesin-NIPBL complex. Great collaboration between ⁦@Hongtao_Yu_Lab⁩ and ⁦@bxc82⁩ lab.
Many thanks to editors’ and reviewers’ efforts! https://t.co/qpvy4vtdqF

[Zhubing Shi @ZhubingShi]

@maozhouhe Thank you!

[Zhubing Shi @ZhubingShi]

@EunheeChoi12 Thanks, Eunhee!