Aging doesn't just change what brain cells do, it changes what they are! New study shows microglia cells replaced over time by monocyte-like inflammatory cells due to DNA methylation changes, consistent with brain aging and dementia resulting from epigenetic information loss👏🧵
Salk scientist Rusty Gage was the first to show that the human brain can generate new neurons well into adulthood, overturning a century of scientific dogma that held the adult brain to be fully developed and incapable of regeneration.
Gage’s discovery of human adult neural stem cells was a landmark event in the history of neuroscience, forever changing how we think about the flexibility and regenerative power of the adult brain.
We’ve now learned where these stem cells are and what cells they can turn into. We’re also getting a clearer sense of how diet, exercise, stress, and disease can influence adult neurogenesis, and how this affects our learning, memory, and mental health.
Read more from the 2000s time capsule in the newest issue of Inside Salk: https://t.co/Toj8ppwJWH
#SalkInstitute #Neuroscience #StemCells #SanDiego #California
Read about our latest contribution to science ⬇️: How do we feel touch? https://t.co/2pXIgHZPsh
(press release) https://t.co/hMOZsVTPGb
Thanks to all the contributors and here's to the next discovery!
Neuroscientist Magdalena Göetz began the world’s first-ever conference for researchers studying cellular reprogramming, differentiating, repair, & regeneration. It was held at CSHL!
https://t.co/r4v6z6UP7X
Thank you to organisers Marisa Karow @karow_lab, Samantha Morris @morris_lab & Barbara Treutlein @TreutleinLab and all delegates for a great 'Novel Technologies for Programming Human Cell Fate' Workshop this week.
https://t.co/wLGs16Fuen
#BiologistsWorkshops
When help is needed, our #mdcBerlin employees come through‼️ An unbelievable € 3,512.80 has been collected in the last two days to support those affected by the severe #TurkeySyriaEarthquake. Thanks to all the people involved❗️Donations will go to Turkish NGO @ahbap 💪
5,562 proteins were found to have tissue-specific enrichment across 32 human tissues.
The majority of them (3,088) are enriched at the protein but not RNA level.
The brain hosts the largest number of proteins that are only enriched at the protein level but not RNA level.
Glad to share our latest work out in @Nature today
We show that human cortical #organoids transplanted into the somatosensory cortex of newborn rats develop mature cell types and integrate into sensory circuits and can influence reward-seeking behavior
https://t.co/pUQt9CbbmM
Through his pioneering research, Svante Pääbo – this year’s #NobelPrize laureate in physiology or medicine – accomplished something seemingly impossible: sequencing the genome of the Neanderthal, an extinct relative of present-day humans.
BREAKING NEWS:
The 2022 #NobelPrize in Physiology or Medicine has been awarded to Svante Pääbo “for his discoveries concerning the genomes of extinct hominins and human evolution.”
"regular caffeine intake improves the signal-to-noise ratio during information encoding, in part through a fine-tuning of metabolic genes while boosting the salience of information processing during learning in neuronal circuits". https://t.co/Swyz0cNAMc
https://t.co/hCz3tSwnWX
Merry Christmas! We got you a new telescope.
The James Webb Space Telescope launched today, beginning a one-million-mile journey to see 13.5 billion years into the past. Follow @NASAWebb and join the quest to #UnfoldTheUniverse: https://t.co/TlYpoUHdJu