Joseph A. Miccio, MD

Father, husband, and radiation oncologist | Assistant Professor @PennStateHershey | former resident @yaleradonc | Pitt Panther fan (H2P)

[Skyler Johnson, MD @sky__john]

This preprint reports "high clinical benefit" of ivermectin + mebendazole in cancer patients. However, the study authors themselves state 'benefit cannot be inferred' due to design limitations.

Let's unpack why.

[C. Jillian Tsai, MD, PhD @CJTsaiMDPhD]

🚨You asked and we delivered - CURB2 Ph3 RCT now allows those assigned to SOC to have the flexibility to stay on same systemic therapy➡️real world practice.
Please consider opening/accruing this trial🙏

@NRGonc @CDNCancerTrials @DrMengWelliver

[Penn State Radiation Oncology @PSH_CocoaBeams]

We’re hiring! Radiation Oncologist opportunity at Penn State Health

Join a growing, collaborative team delivering cutting-edge, patient-centered cancer care across a leading academic health system.

👉 Apply here: https://t.co/7gIIq4J48T

[Abhishek Solanki @abhiAsolanki]

Pleased to share our recently published ASTRO consensus paper in Practical Radiation Oncology on DVH dose constraints for radiation therapy treatment planning, led by my friend Dr. Lindsay Puckett.

https://t.co/IWqckLZF2B

A thread on the goals of this effort 🧵

#RadOnc #ASTRO

[Dr Rishabh Jain @DrRishabhOnco]

Localized prostate cancer management is NOT one-size-fits-all. 🎯

From low-risk to very high-risk and cN1 disease, treatment decisions hinge on risk stratification, imaging, and timing of ADT.

These guideline algorithms bring clarity to:
🟢 Active surveillance vs radical treatment
🟡 Favorable vs unfavorable intermediate risk
🔴 High-risk, very high-risk, and cN1 disease
🔁 Post-treatment PSA monitoring and salvage pathways
📸 BCR workup with PSMA PET-CT and MRI

📘 Evidence-based. Structured. Practical.

🔖 Save for clinics
📤 Share with your unit

@myesmo @esmo_open @OncoAlert @ASCO @ASTRO_org

#OncoTwitter #MedTwitter #ProstateCancer #UroOnc #RadiationOncology #MedicalOncology #GUOncology

[Rahul Tendulkar, MD @RTendulkarMD]

Ever had a case of spurious postop PSA elevation that didn’t make sense? Hint: recheck the PSA with human anti-mouse antibody (HAMA) treatment. Here’s a case where a patient was spared from unnecessary salvage therapy.

[Emre Yekedüz @yekeduz_emre]

☢️New meta-analysis in JAMA Network Open:

🎯Stereotactic body radiotherapy (SBRT) alone for oligometastatic cancer achieved 70% systemic therapy-free survival at 1-2 years, highest in renal (87%) and prostate cancer (78%).

🎯Low toxicity rates suggest SBRT may safely defer chemotherapy in selected patients.

10.1001/jamanetworkopen.2025.49685

@OncoAlert @DrYukselUrun #MedX #Cancer #Oncology @JAMANetworkOpen

[Retro Pitt @RetroPitt]

The Oakland Zoo used to be one of the best student sections in the country. Take a moment to watch the pregame before the Syracuse game in 2011.

[Pitt Panthers @Pitt_ATHLETICS]

left ‘em in (Reese’s) pieces 😼🫨🍫

@Pitt_MBB DOMINATES penn state 80-46‼️‼️‼️

[Jeff Ryckman @jryckman3]

Don’t want to just data dump a bunch of kidney SBRT papers on ya rn (sorry I am enthusiastic about this topic) but in general even for niche solitary kidney scenarios fantastic results median eGFR decline around 13 ml/min plateaus at 2 years so it’s a fantastic option especially for peri-hilar or > 2-3 cm not suitable for thermal ablation as most patients motivated to avoid HD, also associated with 99% 5y local control

[Penn State Radiation Oncology @PSH_CocoaBeams]

Proud of our Radiation Oncology team for giving back to our community.

Together, we donated 141 lbs of food to the Hershey Food bank—helping support families in need and making a meaningful impact beyond the clinic. @PennStHershey

[David Palma, MD, PhD @drdavidpalma]

Here are all the oligomets RCTs.
HRs < 1 in green. @Mat_Guc

[Penn State Radiation Oncology @PSH_CocoaBeams]

🎗️October is Breast Cancer Awareness Month. Radiation treatment is more than a therapy - it's a step toward healing and renewed hope. Every beam is aimed at a future free from cancer. To everyone walking this path; your strength inspires us all. 💗@PennStHershey

[Penn State Radiation Oncology @PSH_CocoaBeams]

📢 Excited to welcome @VinitaTakiar, the new Chair of the Department of Radiation Oncology! We’re excited for the leadership, expertise, and vision Dr. Takiar brings to our team. #Welcome #RadOnc @PennStHershey

[Joseph A. Miccio, MD @JAMRadOnc]

@scserendipity1 @TylerSbrt @aadel_chaudhuri @cwspeers @andreasroder1 @brookmans76 @_ShankarSiva @ResearchWyatt @shiv_smith @SimonMDLord @RenuEapen @AlisonBirtle @mrsprostate @alison_tree @MariamAboian @sophia_kamran @lauren_henke @HimanshuNagarMD @JuanMiguelPechL @ethansgrumps @swoo_rad @Prof_Nick_James @PennStHershey Hah it usually ends up with me holding my son while he “helps” push the jogger

[Jeff Ryckman @jryckman3]

🧵1/

🚨New case report out in Cureus:

Face the Pain: Radiobiological and Clinical Considerations of Re-radiosurgery to the Trigeminal Nerve

👉 A deep dive into a unique case of medically refractory TGN in the setting of a petroclival meningioma.

🔗 https://t.co/jxckq1rugm

[Henry S. Park, MD, MPH @HenryParkMD]

Interested in an updated overview of small cell lung cancer geared towards a general audience? Check out our review article published in JAMA! @Sokim_33 @Annechiangmd @YaleMed @YaleCancer @YaleRadOnc

[Nicholas Zaorsky, MD MS @NicholasZaorsky]

Epidural spinal cord compression (ESCC) scale for cancer metastasis

[Rami Manochakian MD, FASCO Cancer Education @RManochakian]

🚨🔥 1/2 @OncoAlert Hot off the press.

Just published @NEJM in conjunction with presentation on updated data @myESMO #ESMO2024

Results of #ADRIATIC trial of #Durvalumab vs #Placebo after #Chemoradiotherapy in Limited-Stage #SmallCell #LungCancer.

👇🏼
https://t.co/ElbWrwddii