Jacob T. Sanders

Lecturer at @BCMB_UTK. All opinions are my own.

[Cell Press @CellPressNews]

The longest lived people among us, called "supercentenarians," have an abundance of cancer-killing immune cells, study finds.

Learn more in Cell Reports: https://t.co/iFKWukx2c7

Kosuke Hashimoto, Nobuyoshi Hirose, Piero Carninci, Yasumichi Arai, & colleagues
@cellreports

[nature @Nature]

Nature research paper: Precancerous niche remodelling dictates nascent tumour persistence

https://t.co/2ju71dXoDf

[OserLab @Oser_Lab]

Thrilled to share our new work published in Nature (https://t.co/6KIgZiDhMN). We report an exciting new potential therapeutic strategy with a fascinating mechanism of action for cancers with a compromised G1–S cell cycle checkpoint, including SCLC.
https://t.co/8UyaKWbecQ

[Iain Cheeseman @iaincheeseman]

New preprint! We solve a mystery you didn't know existed. Mitotic cells lack new transcription but require ongoing translation. Interphase mRNA half life is only 2-4 hrs. So how do cells arrest in mitosis for hours without depleting their transcriptomes?

https://t.co/2CCq7AgYWS

[Dr. Eddie Ramirez @EddieRDMD]

Journal Nature: Cancer cells can poison attacking immune cells by filling them with defective mitochondria ― dampening the body’s defensive forces and helping the tumor to evade eradication
https://t.co/NIdGJGr2pZ @_atanas_

[Bartomeu Colom @Bartomeu_Colom]

'The Epigenetic Hallmarks of Cancer'
https://t.co/lwSfwuZmYD

[Amy Strom @DNAmyStrom]

Chromatin scientists, want to reorganize genomic loci as you wish?
Out today in Cell--We made a tool that uses surface tension of engineered condensates to reposition DNA loci across microns of space in living cells in just a few minutes: VECTOR https://t.co/914xsicfcV

[Jacob T. Sanders @JacobTSanders_]

@HengLi_UTK

[The Frock Lab @FrockLab]

Eliminating core NHEJ factors reveals two distinct alternative end joining mechanisms. We investigate how one of them collaborates with the DDR to suppress MMEJ. https://t.co/G9cX4GYtNA

[Jacob T. Sanders @JacobTSanders_]

@WhitneyGulledge Turn up?

[Simona Cristea @simocristea]

Incredible resource: analysis of Whole Genome Sequencing data on 10,478 cancer patients spanning 35 types identifies 330 candidate driver genes, including 74 new drivers.

TP53 is a driver in 29‼️tumor types, followed by PIK3CA(18), ARID1A(16) & PTEN (14)
https://t.co/Q6Y00l4F4f

[Samuel Hume @DrSamuelBHume]

The 10 biggest cancer papers of the last 10 years (in my opinion)

1. Blocking PD1 activates the immune response against cancer - especially if the cancer has more mutations

https://t.co/rBCVRcDfvo

[Dawid Walerych - Cancer Fight Research Club @FightCancerClub]

A great food for thought for p53/oncogene nerds was published in @CD_AACR by Z. Wang, @gemmakelly_1, A. Strasser et al.
Is mutant p53 an oncogene or not? David Lane's comment is paywalled, so I thought of my own, in a short🧵below https://t.co/XIennhdHjt

[Alex Georgakilas @GeorgakilasAlex]

CAR-T therapy for multiple sclerosis enters US trials for first time.
https://t.co/fs0ayWUoxI

[Jacob T. Sanders @JacobTSanders_]

It’s an awesome time to be a @Lions fan. Brad Holmes has really built this team tough. What I would give to sit a room with him and just talk.

[BCMB_UTK @BCMB_UTK]

📢📢📢Faculty position in Membrane Biochemistry and Biophysics. Review of application begins November 1st. Apply at https://t.co/lFdMndi2h5.

[Elena Shpak @elenshpak]

Please retweet. A tenure-track Assistant faculty position in Plant Biology is open in the Department of Biochemistry & Cellular and Molecular Biology (BCMB) at The University of Tennessee, Knoxville. Apply at https://t.co/ob3OLbw0yw.

[Science Magazine @ScienceMagazine]

Using modern biological tools, researchers engineered #cancer cells with and without specific chromosome abnormalities, showing how tumors rely on them for survival and clarifying the biological role of aneuploidy.

Learn more this week in Science: https://t.co/aOSEzppfWX

[Jacob T. Sanders @JacobTSanders_]

@rkreienkMDPhD @Progeria @abbybuch @DrMatt84 @vicfanjul @gonzalo_lab Sad I missed you all! Hopefully next time.

[Jacob T. Sanders @JacobTSanders_]

Your thoughts matter. Your dreams matter. Your life matters. YOU matter! I really needed to hear that. This applies to you too!

[Hamid Rokny @HamidRokny]

Very happy to share my PhD student's new paper, PeakCNV, a new AI-based method to identify candidate CNVs in whole genome/exome, published in CSBJ.
Read more here: https://t.co/yDXfKJOwlg

@nigelhlovell, @amin_beheshti, @AliAfrasiabi12
@TyreeIHealthE

#BioMedEng #UNSWscientia