Excited to share the major part of my PhD work finally published in @NatureComms ! Here we investigated the impact of adding CD122-directed IL-2 complexes to radiation and anti-PD1 therapies, and how this affects the systemic anti-tumor T cell response.
https://t.co/Se46y3F92I
@Maria_Carden1 talk is now on YouTube!
📣 Differentiation fate of a stem-like CD4 T cells control immunity to Cancer
@HaydnKissick lab @EmoryMedicine
https://t.co/IpdV6qyII8
Excited to share my PhD work in @ImmunityCP . We show CD4 T cell epitopes related to rejection. Through computational prediction and functional studies in humans and mice, we bridge fundamental research and clinical application. Special thanks to @clarsenEmory and @HaydnKissick!
McManus and Valanparambil et al. showed that nearly identical stem-like (PD-1+TCF-1+TOX+) CD8+ T cells emerged as early as day 5 during chronic and acute LCMV infections. https://t.co/gFcXMZSfUg @rafiahmed_lab@dmcmanus123
Excited to share my PhD work from @rafiahmed_lab. We show how CD8 T cells overcome the inability to predict how long a viral infection will last by making adaptable precursor cells a priori—an elegant strategy for an inherently non-prescient immune system. https://t.co/etxUUtbQg2
Check out our latest paper “Differentiation fate of a stem-like CD4 T cell control immunity to cancer”, led by @Maria_Carden1 now live @Nature https://t.co/CrbGlEdQja . This work examines how CD4 T cell differentiation dictates the outcome of the cancer response. Thread below
I am so excited to share my first author publication, “Differentiation fate of a stem-like CD4 T cell control immunity to cancer” published today in
@nature, detailing the project I’ve been working on in
@HaydnKissick’s lab. https://t.co/byzaSwNkwV
Summary of our paper https://t.co/1CE0c2kHUO on combining JAK inhibitors with anti-PD1 for lung cancer (NSCLC). Part of a bench-to-bedside journey to understand opposing roles of IFN in IO. Wonderful team w @EJohnWherry@divijmathew Caitlin Foley @MMarmarelis@Jbauml et al! 1/13
Check out our new paper shedding light on the mechanism of lenalidomide-mediated improvement of the RT-induced abscopal effect in solid tumor models, published this week in Theranostics 👏👏👏@RenLuo_RAD@ElkeFirat@GabiNiedermann@RadOnc_UKF@DKTK_
https://t.co/4B8vdNwf05
Excited to be back in Paris for #Immunorad2023 – the best radioimmunology conference. This event holds a special place in my heart as it was the first conference I attended during my PhD and now, at the culmination of this incredible journey, I'm honored to be here again.
New #JITC article: Adding liposomal doxorubicin enhances the abscopal effect induced by radiation/αPD1 therapy depending on tumor cell mitochondrial DNA and cGAS/STING https://t.co/xw8X6djxLp @liqunwang3 @RenLuobu @KatOnyshchenko@GabiNiedermann
Had an incredible time at #ESTRO2023@ESTRO_RT, learning from some of the top minds in the field and sharing our latest preclinical data on RT/anti-PD1/IL-2c combo treatment!