Kenny

PhD at Karolinska Institutet, Group Robert Harris. Just here to archive scientific updates and digest :) #Neuroimmunology #microglia #myelin

[Kenny @KeyinGlia]

It is my utmost pleasure to share my lastesr work with the research community. In this study, we uncover how dysregulation of microglial checkpoints can selectively render vulnerable white-matter regions susceptible to age-related damage.

[John Lukens @LukensJohnR]

TGFβ signaling mediates microglial resilience to spatiotemporally restricted myelin degeneration @NatureNeuro

https://t.co/AIbGsLlduB

[Karolinska Institutet @karolinskainst]

Blood-nerve barrier discovery in the peripheral nervous system has implications for disease targeting and treatment. New study published in @JExpMed. Research by @o_harald, @Science_Hunt, @justZeri, @PainLab_KI et al.

[Danielle Beckman, PhD @DaniBeckman]

Fresh from the microscope, some angry microglia (🔴Iba1🟢Hla-dr) attacking some neurons (🔵NeuN) in our monkey #Alzheimers model! #neuroscience #neuroinflammation

[Sten Linnarsson @slinnarsson]

Human brain atlas papers by @kimsiletti @MossiAlejandro @ka_wai_rine
@ErnestArenasSWE @EmelieBraun1 @MiriDanan Rebecca Hodge Trygve Bakken Ed Lein @LarsBorm Elin Vinsland Erik Sundström and many others. With a stunning double cover illustration by @IKapustova

[Bo Peng @BoPengMicroglia]

We are happy to share our latest paper in Nature Aging @NatueAging. In this paper, we dissected the aging process of microglia. More importantly, we developed a model named 3xDR, by which we are capable of introducing aged microglia in the non-aged brain. https://t.co/ijp5WYClhe

[Enric Llorens @Ellorebo]

Thrilled to be hosting the "Cellular Ecosystems in CNS Repair" symposium with @ChristianGoritz on September 13th, 2023 @karolinskainst @StratNeuro https://t.co/3xFJ96Dxth Register here for free: https://t.co/6yHYS9K6yh

[Wei Qin @WeiQinChemBio]

thrilled to see TransitID out! It has been an incredible and unforgettable journey collaborating with an amazing team. A million thanks to my mentor, Alice. This marks a great milestone as a postdoc, and I am eagerly looking forward to embarking on new adventures at Tsinghua.

[Lai Guan NG @lai9uan]

We are thrilled to share our review article: "Origin and Heterogeneity of Tissue Myeloid Cells" with @FGinhoux @ImmanuelKwok #ZhaoyuanLiu in @AnnualReviews of #immunology

https://t.co/Dx5GNMbzLM

[Discovery Immunology Journal @discovimmunol]

🆕 #Ecoimmunology | The wild mouse bone marrow has a unique #myeloid & #lymphoid composition & phenotype

✍️ Andrew Muir & colleagues @LydiaBeckerIII & @UoNLifeSci
@A__Wolfenden @JFennBio @kathelse @andrewmbrass @grainger_konkel @Mair_Iris

#OA 👉https://t.co/ltjGiFIJ7Z

[John Lukens @LukensJohnR]

Myelin dysfunction drives amyloid-β deposition in models of Alzheimer’s disease https://t.co/6G4T17M50m

[Pluchino lab - Regenerative Neuroimmunology @Pluchinolab]

Mechanisms of axonal support by oligodendrocyte-derived extracellular vesicles | Nature Reviews Neuroscience https://t.co/LsvW8Rh3Y0

[Kenny @KeyinGlia]

Happy to share our latest work: Disrupting microglial TGF-β signaling triggers region-specific pathology in the spinal cord https://t.co/fgzOe1gveW

[Kenny @KeyinGlia]

@Jessie_JSRCDJ Great job and nice work! Congratulations!!!👍

[Kenny @KeyinGlia]

Big congrats!!! 👏👍🥳

[Jun Wang @Jessie_JSRCDJ]

Happy to announce that our work has been published in J Neuroinflammation！ Congratulation to everyone in the lab! Microglial aryl hydrocarbon receptor enhances phagocytic function via SYK and promotes remyelination in the cuprizo… https://t.co/64ArfgKfqv

[Kenny @KeyinGlia]

Congrats to my fellow colleague from Fudan University on publishing her first first-author paper: Activation of TRPV1 receptor facilitates myelin repair following demyelination via the regulation of microglial function https://t.co/DugPuFwrdF

[Kenny @KeyinGlia]

A common framework of monocyte-derived macrophage activation https://t.co/OulqMdA3U6

[Howard L. Weiner, MD @weinerlabhms]

Spoke at FOCIS Symposium on Neuroimmune Interactions in San Francisco on "Modulation of Microglia with Nasal Anti-CD3 to Treat Progressive MS and Neurodegenerative Diseases". Nasal Anti-CD3 can not only be applied to MS but to AD, ALS & traumatic brain injury. Many applications!

[Federico De Ponti @FedericoDePont1]

Massive effort from @Anandamirch and co-authors showing how hypoxemia shapes the immune response in the lung during acute lung injury. Superb paper!! Out now on @NatImmunol.
Also, happy to share the preview that me and my mentor @KC_DC_01 wrote! 🥳🥳🥳

https://t.co/KyGvsRqZQr

[EMBO Reports @emboreports]

Topoisomerase 1 is upregulated in activated #microglia and the myeloid-specific delivery of the TOP1 #inhibitor #topotecan using a novel #nanosystem reduces #neuroinflammation and ameliorates #MultipleSclerosis-like #disease progression.

-> https://t.co/1uu5shaonU

[Kenny @KeyinGlia]

@keyi_G Thank you Keyi for the great help! Looking forward to hearing your good news soon 🤞🎉

[Kenny @KeyinGlia]

Our recent paper is online now @emboreports: Myeloid cell‐specific topoisomerase 1 inhibition using DNA origami mitigates neuroinflammation | EMBO reports https://t.co/0o5Uy0jbGP
Thank all the collaborators and contributors! ❤️