Kimberly Linback

A Wife. A Mom. A Daughter. A Sister. A Friend. A Learner. A work in progress

[Patrick Collison @patrickc]

The 2026 @arcinstitute Virtual Cell Challenge just launched. The grand prize is $100,000, sponsored by @NVIDIA, @10xGenomics, and @UltimaGenomics.

There's a lot of interest in virtual cells these days: ML models of cells that can complement wet lab experiments. (You'll always need the wet lab to validate results, of course. But ML models can in principle search far more efficiently.)

A practical challenge in the field is that benchmarking is quite difficult: cells are very complicated, and it's not a priori obvious how to compare two different models.

So, inspired by the CASP protein folding contest, we're running the Virtual Cell Challenge to create a standardized way for teams around the world to compare the efficacy of different approaches, to spread awareness of what works, and ultimately -- we hope -- to support faster progress overall.

https://t.co/KMUYwidz7r

[Eric Topol @EricTopol]

Impact of belly fat on cardiovascular outcomes.
Missed in both directions by BMI.
Waist circumference and/or waist-to-hip ratio measurements are key.
AF-atrial fibrillation, HF-heart failure, CHD-coronary heart disease
@JACCJournals
https://t.co/m7QoMQ2CUi

[Sahil Bloom @SahilBloom]

A mentor once told me this: Just be unapologetically yourself. The moment you start filtering yourself to be liked is the moment you start attracting relationships that need constant maintenance. Do you. The right ones will stick, the wrong ones will walk. That’s a blessing.

[Johnson & Johnson @JNJNews]

We’re committed to helping improve sight for more than 40 million patients in the U.S. and around the world.

This week, we announced a more than $1 billion investment in Jacksonville, Florida to strengthen our Vision operations.

As part of our $55 billion U.S. investment in manufacturing, technology and R&D, this commitment includes a new distribution facility, and advanced manufacturing and packaging technologies, to expand capacity and enhance supply chain resilience.

Learn more: https://t.co/vRSh10gNLl

[WeRateDogs @dog_rates]

This is Sadie. She's a service dog who was honored with her own bone diploma at her human's college graduation. Worked very hard in all her classes and is glad her efforts didn't go unnoticed. 14/10

[Vala Afshar @ValaAfshar]

“Life will always be hard and life will also always be beautiful.”

The beautiful joy of clearly seeing mom for the first time

[Nate Krah @N8Krah]

🧬 New paper out in @Nature! We used CRISPR to selectively kill cancer cells based on a single-letter mutation in their RNA. The story I want to highlight: KRAS — one of the most notorious drivers of human cancer. A short thread on what we found 🧵

[Science Magazine @ScienceMagazine]

For decades, biology textbooks have enshrined a simple rule: DNA is made by copying a template. After one enzyme unzips a DNA double helix into separate strands, another called a polymerase builds a complementary sequence, base by base, for each strand. Presto: two copies of the original DNA.

But new research into how bacteria defend themselves from viruses now shows this synthesis rule isn’t absolute.

Now, a team describes a bacterial enzyme that synthesizes DNA without a nucleic acid template, using its own structure as a guide.

Learn more: https://t.co/TeUWvyO0OD @NewsfromScience

[Eric Topol @EricTopol]

more on this @thetimes https://t.co/iePGD3VpsD
The cliché: "I don't want to know because there's nothing you can do about it" is obsolete

[Eric Topol @EricTopol]

A good, succinct summary of the 3 new studies by @grok

[BMJMedicine @BMJMedicine]

Does your workout variety matter for long-term health?

New research from Han Han and colleagues examines the associations of long term engagement in individual physical activities and physical activity variety with the risk of death.

https://t.co/vV04xPRN4q

[Drug Channels @DrugChannels]

Vertical integration meets scale?

@amazon $AMZN is now the largest provider of employer-sponsored health insurance.

That's a massive platform for building and scaling a healthcare business, starting with selling products and services to itself.

Source: @mark-farrah-associates https://t.co/mJR4ZFLeyP

[Sahil Bloom @SahilBloom]

A hill I’m willing to die on: Nothing will improve your quality of life more than proximity to people you love. It’s worth more than any job will ever pay you.

[Ryan Holiday @RyanHoliday]

3 Life-Changing Habits From The Stoics That You Can Apply Today:

- Pause before you respond
- Go for a long walk every day
- Challenge yourself physically

[James Clear @JamesClear]

If you want a recipe for unhappiness, spend your time accumulating a lot of money and let your health and relationships deteriorate.

[Eric Topol @EricTopol]

Get this: Coffee suppressed atrial fibrillation!
Unexpected results for recurrence from a randomized trial in participants after cardioversion from AF
#AHA25 @JAMA_current ☕️ https://t.co/70dPI2R84C

[Ryan Holiday @RyanHoliday]

“Whatever happens, I can derive some benefit from it.” — Epictetus

[Kimberly Linback @KimLinback]

This year’s Nobel Prize in Medicine exemplifies “if you want to go fast go alone but if you want to go far go together”. Congratulations, I cannot wait to see where your Tregs work will take medicine.

[The Nobel Prize @NobelPrize]

This year's medicine prize was shared by three individuals, Mary Brunkow, Fred Ramsdell and Shimon Sakaguchi. Did you know it's been shared by three people 40 times?

Check out the statistics for the Nobel Prize in Physiology or Medicine.

#NobelPrize

[Vala Afshar @ValaAfshar]

So many are busy measuring what is easy to measure as opposed to what is important.

[Vala Afshar @ValaAfshar]

Stop bragging about how busy you are. People are not interested in your schedule.