Kirmizis Lab

Epigenetic Regulation of Gene Expression

[Kirmizis Lab @KirmizisLab]

#Chromatin as metabolite reservoir fuelling lipid synthesis.
The work was led by @Evelchar. Many thanks to collaborators @BonaldiTiziana @RobertaNoberini, @hectorkeun, Volker Behrends, @LabStrati, to @embojournal editors and to anonymous reviewers.

https://t.co/JSHjkgZ1xB

[Marcus Buschbeck and Lab @MarcusBuschbeck]

PhD opportunity

An opportunity to do a PhD at the intersection of industry and academia while being part of a vibrant network.

👇

[Kirmizis Lab @KirmizisLab]

Congrats at @ArielKlavaris for leading this study on a new histone H2AX modification, and many thanks to all have have contributed!

[Ariel Klavaris @ArielKlavaris]

📢 Our new paper is out! @KirmizisLab
H2A.X is N-terminally acetylated by NAA40–a novel histone mod responsive to UV irradiation.
Thanks to all authors @BonaldiTiziana @CosKouf @ChristiDemet @N_Dietis anonymous reviewers & @EpigenChromatin Editorial team.
https://t.co/Foa6wiarGP

[Marcus Buschbeck and Lab @MarcusBuschbeck]

Last opportunity to join our network on nuclear metabolism as PhD student.

[Kirmizis Lab @KirmizisLab]

Congratulations Poly!!

[Polymnia Georgiou @PolymniaG]

📢Hot off the press! Excited to share our new paper in @molpsychiatry on the role of ERβ in stress vulnerability. Thanks to all of the authors involved @pzanos @BrianMathur1 @KirmizisLab @Michael_Patton1

https://t.co/Dhu8QNZ59m

A thread🧵

[Kirmizis Lab @KirmizisLab]

Congrats to our postdoc @Evelchar for receiving the Cyprus Young Researcher award in Life Sciences awarded by @ResearchCy for her exciting work on the crossroad of #epigenetics and #metabolism Wishing her continued success as she progresses her career to independent investigator

[Shilatifard Lab @ShilatifardLab]

Have you ever wondered why we have testis specific genes & what happens if their mechanism of silencing is misregulated in other cell types. Well, superb study by Bin Zhang in collaboration with @LuWangLab showed that such ectopic expression can drive cancer & can be targeted for therapeutics https://t.co/v6OBAIMbih @NUFeinbergMed @ScienceMagazine @ScienceAdvances @AACR @NU_BMG_SQE

[Marcus Buschbeck and Lab @MarcusBuschbeck]

HURRY UP! ONLY 3 DAYS LEFT!

To apply for a PhD position in our lab
@carrerasIJC in Badalona-Barcelona
Projects at the intersection of metabolism and chromatin
Starting -/+ September 2025
Being part of a @MSCActions network.

Apply here:
https://t.co/mLuKpRqt86

[Mark Dawson @MAF_Dawson]

We are looking for a talented postdoctoral bioinformatician ⁦@TheDawsonLab⁩ to work with us on single cell multiomics incorporating lineage tracing and spatial technologies- we specifically want someone curious, fearless with a licence to innovate!! https://t.co/gBpTDjb3kI

[Inti De La Rosa Velazquez @IntiOmics]

Great paper! Congratulations @METorresPadilla and team!
An atlas of transcription initiation reveals regulatory principles of gene and transposable element expression in early mammalian development: Cell https://t.co/vCiR5QtQ0M

[Yael David @Yael_David__]

I am extremely proud to see our work about Hepatitis B now published in @CellCellPress.

From basic research to identifying the key step of infection & a potential first drug for curing this devastating disease. This has been an incredible journey.🧵

https://t.co/wfdbwQmw4J

[Kirmizis Lab @KirmizisLab]

****Available PhD position in our group****
Offering one of the below funded positions with start in September 2025. More on the specific project here: https://t.co/Htd1XjQZAp

[NUCLEAR-DN @NuclearDn]

🚨 We’re Hiring! 16 PhD opportunities in an emerging research field! 🚨@MSCActions

Are you ready to dive into innovative research in metabolic regulation of genome function in stem cells and cancer?

🔗 Learn more & apply now: https://t.co/dOp8I6dCM2

#PhD #CancerResearch #MSCA

[NUCLEAR-DN @NuclearDn]

🚨 We’re Hiring! 16 PhD opportunities in an emerging research field! 🚨@MSCActions

Are you ready to dive into innovative research in metabolic regulation of genome function in stem cells and cancer?

🔗 Learn more & apply now: https://t.co/dOp8I6dCM2

#PhD #CancerResearch #MSCA

[Marcus Buschbeck and Lab @MarcusBuschbeck]

OPPORTUNITY TO JOIN US!

Two of these PhD positions are available in our group.

We want to know how nuclear metabolism impacts chromatin regulation in leukaemia.

You as well?
> Then check this out!

[EpiCypher, Inc. @epicypher]

Fun #epgienetics review for Sunday!
Histone PTMs and DNA-templated processes (e.g. transcription) are deeply linked, but the mechanisms driving their cross-talk remain unclear.

López-Hernández et al. cover the latest research on this key question - Enjoy!
https://t.co/2f9lf4D8OM

[Kirmizis Lab @KirmizisLab]

Very insightful review from @NAT_machinery on protein N-terminal acetylation biology and its impact on physiology.

https://t.co/lv0c8jYwB9

[Epigenetics Research at Helmholtz Munich @epigeneticsHMGU]

🚀 2025 INTERNSHIP CALL IS NOW OPEN!

Ready for an adventure this summer? Join our #Epigenetics Summer Internship at @HelmholtzMunich! Dive into AI, stem cells, chromatin and cutting-edge research, while gaining wet and dry lab experience.

Apply now! 👉 https://t.co/swsPXKChJi

[Trefely Lab @trefely]

We have an exciting postdoc opportunity at the interface of metabolism and epigenetics! 🔥🧬

The project will investigate novel metabolic factors driving diabetic cardiomyopathy🫀, and test targeted dietary interventions 🍽️

For more detail and to apply:
https://t.co/IKMJmMAQMo

[Maria Christophorou @MAChristoLab]

Thank you @J_Cell_Sci for giving us the opportunity to write this article. We thoroughly enjoyed it!

[Maria Christophorou @MAChristoLab]

We drew knowledge and inspiration from the work of Arturo Zychlinsky, @VeniPap, @HarmitMalik, Steven Henikoff, @VashKurdistani, @KirmizisLab, Denisa Wagner, @kmartinod, Li Yang, @megeblad, Anne Brüstle and many others.

[Kirmizis Lab @KirmizisLab]

@MAChristoLab @VeniPap @HarmitMalik @VashKurdistani @kmartinod @megeblad Congrats Maria et al. Very insightful!