For 15+ years, our work has shown that histone-modifying enzymes do more than just their catalytic jobs. They also have important non-catalytic roles. Dr. Zibo Zhao just published a great review on COMPASS family enhancer monomethylases and discusses how their loss creates new druggable vulnerabilities. https://t.co/VBHYgAFJZo Her findings are now in the clinic for treatment of cancers bearing MLL3/4-COMPASS mutations Fingers crossed! @NU_BMG_SQE@NUFeinbergMed@theNASciences@theNAMedicine@CellPressNews@ScienceMagazine@Nature@NatureCancer@MolecularCell@zhao_zibo
Really pleased to announce that Dr. Anish Thomas from the NCI -here at AACR 2026- will be joining the @LurieCancer Center as Medical Director of our Lung Cancer Program and Director of the new center for Cancer Metastasis. An exceptional physician scientist and leader.
LCRF is pleased to announce this year's 2025 Scientific Grant Program awards. Eleven awardees received a total $1.65 million in funding for new #LungCancer research. Read more about these scientists and the focus of their studies. https://t.co/ZOee0WHJCO
The @LurieCancer (LCC) went thru competing renewal of NCI designation. For a 2nd time we got "exceptional" ranking. The NCI site visit team gave a "perfect exceptional" (equivalent to 10). LCC is one of few in the nation and the only one in IL to ever achieve exceptional status.
Read about some of our faculty’s effort at Northwestern Medicine Biochemistry and Molecular Genetics in developing targeted therapeutics towards human disease! @NUFeinbergMed@NU_BMG_SQE https://t.co/hHkvhDWi1L
Have you ever wondered why we have testis specific genes & what happens if their mechanism of silencing is misregulated in other cell types. Well, superb study by Bin Zhang in collaboration with @LuWangLab showed that such ectopic expression can drive cancer & can be targeted for therapeutics https://t.co/v6OBAIMbih @NUFeinbergMed@ScienceMagazine@ScienceAdvances@AACR@NU_BMG_SQE
Excited to share our latest work, showing GATA6 is a critical regulator in colorectal cancer and 3D genome organization. Led by Huijue, Zoe and thanks to our wonderful collaborators @LuWangLab and Dr. Guanyu Yang. @LurieCancer@NUFeinbergMed
https://t.co/j7yRlf0Kn1
Northwestern Medicine investigators have discovered that inhibiting a chromatin remodeling complex associated with a particular gene in small-cell #LungCancer cells may decrease cancer cell differentiation and tumor growth, per @NatureComms.
https://t.co/pB4OBEoUnW
Very excited to share our latest work on the function of POU2F3/POU2AF2 in mediating SWI/SNF-dependent transcription in small cell lung cancer
https://t.co/CjghVPl6N0