Lucia Trastulla

[Lucia Trastulla @LTrastulla]

Keep an eye on the project GitHub https://t.co/aSU846PFu5 for future developments! 🚀

[Lucia Trastulla @LTrastulla]

🎉 Super thrilled to announce my PhD work is finally out.🥳 This work moved a step forward towards personalised medicine paradigms. Huge shout out to all the amazing co-authors, ZillerLab and @IorioLab for making this possible 🙌 https://t.co/D7QW8b3IDm

[Lucia Trastulla @LTrastulla]

Huge congrats to Dr. @Ale_Vinceti for the amazing defence. And thanks so much to @IorioLab and @Francesco_i0ri0 for this beautiful years and for the opportunity to be part of such an amazing team ❤️

[Christine Rummel @ChK_Rummel]

Delighted to share that my first author paper is online. We used massively parallel reporter assay, single cell CRISPRi, iPSC derived neurons, and OMICs to functionally annotate schizophrenia GWAS variants. Check this out: https://t.co/uSjhSQh673
@ImprsTp @mpi_psychiatry #mpra

[Lucia Trastulla @LTrastulla]

Lucky to be in such a great lab and to work with amazing people❤️

[Lucia Trastulla @LTrastulla]

Huge thanks to all the collaborators (Prof. Müller-Myhsok, Prof. Schunkert, @Prof_TGSchulze, @AlexanderTeumer) and all the individuals taking part in the so precious genetic studies (@uk_biobank, @PGCgenetics, #CARDIoGRAM, #PsyCourse, #SHIPTREND)

[Lucia Trastulla @LTrastulla]

The preprint from my PhD work in the lab of Prof. Ziller at the @mpi_psychiatry is finally out!
https://t.co/kTaegPHBgA

[Lucia Trastulla @LTrastulla]

To achieve this, we developed a new pipeline called CASTom-iGEx that operationalizes individual-level genotype data to interpret personal polygenic risk and identify the genetic basis of clinical heterogeneity.

[Fabrizia Pipicelli @fabripipicelli]

Very excited to share my first-author publication on the role of extracellular vesicles in interneuron specification! @silvianeurompi
@NataliaBaumann7
@denisjabaudon
@AndreaForeroE
@rossdigiaimo
@RebeccaB0n
@ScienceAdvances
https://t.co/cz8RHTxC8P

[Lucia Trastulla @LTrastulla]

@IorioLab at its best! Great poster session at #EuroCancerDepMap @ausavino @Ra_LeNoir @Ale_Vinceti @RiccardoRDL

[Lucia Trastulla @LTrastulla]

@Francesco_i0ri0 @uperron3 @NIH @Ra_LeNoir @Target @OpenTargets Yes, of course 😅

[Lucia Trastulla @LTrastulla]

Exciting poster session at the @NIH during the SSACB. It was very insightful to discuss our method for correcting gene independent effects of combinatorial CRISPR-Cas9 screenings. Picture courtesy of @Ra_LeNoir, random clothes due to delayed luggage courtesy of @Target

[Human Technopole @humantechnopole]

📢 Calling all scientists!
Join us for the 1st European Cancer Dependency Map Symposium #EUDepMap with top researchers from @Humantechnopole @emblebi @sangerinstitute @ETH_en on cutting-edge research on cancer vulnerabilities and therapeutic targets.
https://t.co/ybZxdzh6Hu

[Human Technopole @humantechnopole]

Our @Ale_Vinceti from @IorioLab of @Francesco_i0ri0 presents new tools to identify reference gene sets of minimal size allowing supervised analyses of scale-limited #CRISPRCas9 knock-out screens, while having a reduced impact on the screen size.
https://t.co/A3NXVCyH13

[Lucia Trastulla @LTrastulla]

Thanks to coauthors @DrFranVazquez @CancerDataSci @Francesco_i0ri0,
the @MolSystBiol journal, and to @OpenTargets @CancerDepMap and @humantechnopole for supporting this work

[Lucia Trastulla @LTrastulla]

Our review from @IorioLab in collaboration with colleagues at @broadinstitute @CancerDepMap is finally out https://t.co/22DMjGuHfa! Can computational methods aid at estimating the quality of cancer cell lines as in vitro models for tumours?
Highlights in this 🧵

[Lucia Trastulla @LTrastulla]

to conclude, large characterisations of CCLs as well as the development of computational methods to align and compare cancer models and tumour patients will be essential in the near future to the realisation of the personalised medicine paradigm 11/11