LeDoux Lab

A behavioral neuroscience lab dedicated to understanding the ways in which the brain forms, stores and retrieves memories about threatening events.

[LeDoux Lab @LeDouxScience]

Very proud and happy for Rodrigo @LeDouxScience !

[Rodrigo Triana-Del Rio @RodrigoTrianaD2]

awardee with The Leon Levy Fellowship 2020!, exciting news for my research plans!! 🧠🎉💪, supported by the best team @LeDouxScience!

[Angelos Krypotos @angelosvankr.bsky.social - (Ψ) @AngelosVanKr]

New paper: "Induction of conditioned #avoidance via mental #imagery". New article available at Behaviour Research and Therapy, with @G_Mertens, Leer, & Engelhard! (https://t.co/E2zJOUznUe)

[Tiago Branco @trabranco]

"defensive responses like fleeing or freezing can co-occur with feelings of fear, not because the neural processes underlying these two kinds of events are intimately entwined in the amygdala, but instead because the events have the same starting point."

Completely agree!

[Stefanie Poll @neuropoll]

Did you ever wonder what happens to memory in Alzheimer's disease? We found that the memory trace is still there, but impaired by interference with other neuronal ensembles. Like a noisy radio channel. Check it out:
https://t.co/q6k58NetpN
@DZNE_en @DZNE_de

[Joseph E. LeDoux "The Four Realms of Existence" @theamygdaloid]

"Thoughtful Feelings" is a new My Word article in Current Biology. It's an overview of my ideas about what emotions are. Thank you @GeoffreyNorth1 for publishing these "thought pieces."
https://t.co/LLhC8Qnb5G

[Barry C Smith @smithbarryc]

Great talk by @hakwanlau at Consciousness Club @WCHN_UCL dealing with which creatures are conscious and ending with suggested clinical treatments for fear and phobia. Thanks to @smfleming for organizing

[Stefan Remy @SR_neurostar]

New preprint from our lab! On our quest to understand how neural activity drives behavior we made a big step forward. Find how we quantify and map DeepLabCut annotated behavior using Deep Variational Autoencoders. VAME GitHub Toolbox available. https://t.co/RoGhuopa67

[Tiago Branco @trabranco]

New preprint from the lab on how the retrosplenial cortex and the superior colliculus help mice find their way home when they are scared. Led by the fantastic duo @RubenDVale and Dario Campagner. #gimmeshelter

https://t.co/eWxFXNqVah

[Wei Ji Ma @weijima01]

Confused about confidence?

Bored with Bayes?

Tired of 2-AFC?

Join us for a virtual journal club:

Monday May 4th
at 12:30 New York time
on https://t.co/jeZ4kWmkpA

@hsinhungli and I will present our paper on multi-alternative confidence https://t.co/UF1ZuM4cqf

[Matteo Carandini @MatteoCarandini]

It's finally out! Congratulations @ArminLak. The paper is here: https://t.co/DkY80l6ZlT

(and it *will* be Open Access -- working on it right now)

[UCL Neuroscience @uclnpp]

New preprint from @candelabellot in @MacAskillAF lab @uclnpp! Push-pull regulation of exploratory behavior by two opposing hippocampal to prefrontal cortex pathways https://t.co/ZXxTcQN0kh

[LeDoux Lab @LeDouxScience]

"A cortico-collicular circuit for accurate orientation to shelter during escape"

[Tiago Branco @trabranco]

New preprint from the lab on how the retrosplenial cortex and the superior colliculus help mice find their way home when they are scared. Led by the fantastic duo @RubenDVale and Dario Campagner. #gimmeshelter

https://t.co/eWxFXNqVah

[Maria Diehl @DrDiehl_neuro]

Excited to share a preprint of the final work from my postdoc lab where we show that prelimbic cortex bidirectionally controls platform-mediated active avoidance. @jorgeiravedra @rojasbowe @JonathanMoranPR @vpvalentin_
https://t.co/GGG3J0dVB4

[Il Memming Park @memming]

#BRAINInitiative virtual event in 1.5 hr on "How Can Dynamical Systems Neuroscience Reciprocally Advance Machine Learning" #machinelearning https://t.co/4PpGEXu5bq featuring @rajankdr @KordingLab @xaqlab @nathanieldaw

[LeDoux Lab @LeDouxScience]

'The central amygdala recruits mesocorticolimbic circuitry for pursuit of reward or pain'

[Anand Gururajan @anandgururajan]

'The central amygdala recruits mesocorticolimbic circuitry for pursuit of reward or pain' by @accumbenshelley in Kent Berridge's lab. Congrats!!! https://t.co/1lcP7NytJ3

[BryanRoth @zenbrainest]

Looking forward to speaking @StanfordBrain today at 12 PM pacific on "New technologies for neuroscientists (and others"

https://t.co/SUCbMwG4mj

[LeDoux Lab @LeDouxScience]

Context- and Subgroup-Specific Language Changes in Individuals Who Develop PTSD After Trauma

[Catarina Cunha @clemoscatarina]

Context- and Subgroup-Specific Language Changes in Individuals Who Develop PTSD After Trauma https://t.co/gVFBiEOiOY

[LeDoux Lab @LeDouxScience]

Amelioration of obsessive-compulsive disorder treated with one epigenetic drug, great job
@clemoscatarina !

[Adam Carter @CarterAG]

Our new study with @GordFishell and @JDimidschstein is now on bioRxiv, showing how the ventral hippocampus engages CCK+ interneurons in the prefrontal cortex, with endocannabinoid modulation of inhibition at only a subset of L5 pyramidal cells:
@theXL92
https://t.co/kZRB0LSyH5

[Simon Peron @PeronLab]

Congrats @TinaVoelcker! This is one of those really pretty results I think a lot of folks suspected was true but never confirmed. Until now.