Dr Michelle Percharde

PI and @UKRI_News Future Leaders Fellow @MRC_LMS @imperialcollege. Loves stem cells, transposons, chromatin, cycling, proud WomanInScience. same handle at 🦋

[Dr Michelle Percharde @MPercharde]

🚨Symposium alert! 🚨 Next edition of our biennial stem cell symposium is 4th Dec 2025 - focus on metabolism and development. Sponsored by @bsdb. Great lineup of speakers, hosted @MRC_LMS in London. Chaired by me and @VAzuaralab. Registration is open.

https://t.co/nFkOu67uUZ

[Dr Michelle Percharde @MPercharde]

@BPernaute @ERC_Research Wow congrats Barbara(za)!!

[Dr Michelle Percharde @MPercharde]

BIG thanks all authors for their invaluable contributions inc @Paul_Chammas @BryonyLeeke @XieSheila @Less_Sepulveda @rna_mcmanus @its_GeorgeYoung & those not on X, as well as @MRC_LMS and @UKRI_News funding #UKRIFLF

[Dr Michelle Percharde @MPercharde]

Maybe my last post here? ---> Follow the lab on 🦋🦋🦋 ! Happily retweeting new preprint: @Paul_Chammas postdoc paper @MRC_LMS , teasing apart Dux vs MERVL in the 2C-like state. Not all 2C-like cells are created equal....

[Paul Chammas @Paul_Chammas]

Happy to share our latest #preprint showcasing the work done during my postdoc in the lab of @MPercharde at the @MRC_LMS. We used CRISPRa to disentangle the close relationship between Dux and MERVL elements in the induction of the 2-cell like state. https://t.co/F40Vfn6KVR (1/8)

[Rachael Barry @DrRBarry]

We're hiring. I'm now officially a UKRI Future Leader Fellow & looking for a driven Research Technician to join my team! If you’re passionate about advancing gut health & cancer biology, I’d love to have you on this journey @ImperialMDR @imperialcollege
https://t.co/RQxFl4p6Md

[Jamie Hackett @hackettlab]

📢Postdoc available! We are looking for curious minds to answer big questions using epigenome editing

Join us at @EMBLRome - we offer training, supportive environment, top salary and scientific excellence. Also - sun, culture & Italian food😉

Info+apply:
https://t.co/1LzuHBds20

[Dr Michelle Percharde @MPercharde]

@Alexis_Barr @kylelmorris @thermosciEMSpec @JEOLEUROPE I feel quite stressed looking at it 😂

[Dr Michelle Percharde @MPercharde]

SPA = single particle analysis? @champneys

[Kyle L. Morris @kylelmorris]

Weekend spa hotel report: I can’t help but notice design parallels with modern #cryoem microscopes, in this ‘Cryo therapy treatment’ device I found on site.

I doubt CRYOACTION is trade marked, @thermosciEMSpec @JEOLEUROPE in case you like the look.

[Dr Michelle Percharde @MPercharde]

Very cool findings for a role for LINE1 in human ESCs from @MRSantosLab . Remarkable to have partial similarities to its role in 🐭

[Miguel Ramalho-Santos Lab @MRSantosLab]

📣Sharing the latest research from the @MRSantosLab, just released on bioRxiv! We found LINE1 RNA promotes nuclear compartmentalization to repress the 8-cell state in human embryonic stem cells.
https://t.co/uE06Xx3QcY

👇Key findings:

[Dr Michelle Percharde @MPercharde]

@bulutkarslioglu @HK_Heidar @NRivron Amazing work and finally well deserved 🙌🏻

[Aydan Bulut-Karslioglu @bulutkarslioglu]

Our new work is out today! Long time in the oven, this has been a really fun and informative collaboration led by Dhanur Iyer in my lab and @HK_Heidar from @NRivron lab. We show that human embryonic cells have an inherent potential to regulate their developmental timing.

[Dr Michelle Percharde @MPercharde]

@JakobssonLab

[Teresa Rayon @t_rayon]

🚨PhD position in the lab in a collaborative project with @bitbio

📩 interested? get in touch for further info

🔁Please RT and share with fitting candidates

[Vicki Metzis @metzisv]

Interested in how cells make decisions? Want to build new tools and model embryonic development using ESCs?

Come join us @MRC_LMS! We have a #postdoc position open in the area of gene regulation, stem cells and mouse development.

See how to apply here: https://t.co/MePCx3blRC

[Lila Allou @lila_allou]

📢3-year postdoctoral fellow position available

Interested in gene regulation and deciphering the molecular mechanisms of human disease, join us at the @MRC_LMS in the beautiful city of London

For more details, please visit https://t.co/K1hrM3iVje

✉️[email protected]
🙏RT

[Dr Michelle Percharde @MPercharde]

@bulutkarslioglu @lila_allou @MRC_LMS You can always share with me 😍😜

[Dr Michelle Percharde @MPercharde]

Welcome Lila to the @MRC_LMS and to the best floor in particular! 😜

[Lila Allou @lila_allou]

Happy to officially join the @MRC_LMS as MRC Investigator and Programme Leader Track. Excited to be surrounded by outstanding, nurturing, collaborative colleagues! For more details, please visit the Lab webpage Genetic Variations and Disease, Lila Allou (https://t.co/kcBOxHWfCT)

[Miguel Ramalho-Santos Lab @MRSantosLab]

Postdoc positions in the @MRSantosLab! Please RT. Upcoming departure of several very successful lab members + new funding = postdoc positions! Exciting new avenues in mouse development, hypertranscription, dormancy and environment-epigenome interactions.
https://t.co/1vyyptbUSb

[Dr Michelle Percharde @MPercharde]

🤫🤫

[Geoff Faulkner @Faulkner_Lab]

I happily wrote a Preview for the recent HUSH2 story @MolecularCell from the Tchasovnikarova lab

Preview:
https://t.co/g3RYbRZDrK

Article:
https://t.co/xkjkWKwXkC

The HUSH-HUSH2 link from L1 transcription to innate immunity could complicate efforts to target L1 in disease.

[Hakan Bagci @hknbgc]

Very happy to announce the publication of our recent study “Competition shapes the landscape of X-chromosome-linked genetic diversity” in Nature Genetics

⁦@MRC_LMS⁩ ⁦@ImperialMed⁩ ⁦@imperialcollege⁩ ⁦@NatureGenet⁩ https://t.co/2aHubld8Hj