Jon Markert

Postdoc @HarvardMed. CryoEM and anything chromatin or transcription. views are my own

[Manuel Osorio Valeriano @mosoriov91]

I’m very happy to share our latest work on the ParABS system. We investigated the dynamic interaction between the ATPase ParA and the CTPase ParB mediating chromosome segregation in Myxococcus xanthus. I would like to thank all the people involved.

[Jon Markert @MarkertJon]

Our work providing the mechanistic basis for SETD2 function is finally out! We demonstrate SETD2 requires active transcription to facilitate H3K36me3 deposition!

[Lucas Farnung @LucasFarnung]

Ever wondered how transcription choreographs histone modifications? Our work reveals the basis of co-transcriptional H3K36me3 by SETD2. We visualize how a histone writer coordinates with the transcription machinery! This is the magnus opus of @MarkertJon https://t.co/g27t5Rw5RY

[Tycho Mevissen @TychoMevissen]

Excited that our work on transcription-coupled DNA repair is now published @CellCellPress! We recapitulated TC-NER in Xenopus egg extract and identified STK19 as a core repair factor that couples stalled Pol II to TFIIH. 🧬🐸

➡️ https://t.co/0SDr81nzhu

[Jon Markert @MarkertJon]

@bmart87 Good luck Ben! Your questions and insights in meetings will be missed!

[Zhipeng A. Wang @ZhipengA]

Hiring! Seeking motivated postdocs, technicians, and graduate students for our new lab at the University of Miami Miller School of Medicine. Dive into protein chemistry and chemical proteomics to explore cancer and aging. #ZwangLab #UMiami #Research
https://t.co/NwnK64DLiF

[Melissa Hoyer @hoyer_melissa]

I am happy to share that I will be starting an assistant professor position at the Van Andel Research Institute @VAInstitute in the Department of Neurodegenerative Science. My lab is opening in July, and I am currently hiring: https://t.co/cYhZuzMtQh and https://t.co/0m8owzgZOo

[Jon Markert @MarkertJon]

@LugerLab @NicoleHoitsma What a strange H3 tail! Congrats Chelsea and all!

[Zhipeng A. Wang @ZhipengA]

biology methods for understanding protein post-translational modifications in cancer & aging. Excited for this new journey! Looking to hire passionate postdocs, technicians, and grad students. Join us! [Main Webpage: https://t.co/NwnK64Ej8d] #research #Careers

[Jon Markert @MarkertJon]

Congratulations @hoyer_melissa and everyone else involved!

[Lucas Farnung @LucasFarnung]

Our paper on the structure of the complete Rpd3S-nucleosome complex is now out in Nat Comm: https://t.co/Y5FyXjkoED. Congrats to @MarkertJon and co-corresponding author @seyvos ! This is the second HDAC-nucleosome structure from Jon this year. Amazing!

[Jon Markert @MarkertJon]

@LugerLab Congrats Karolin! Great scientist, even better mentor!

[Jon Markert @MarkertJon]

@JLeeLab Thanks Jason!

[Lucas Farnung @LucasFarnung]

Our story on the complete Rpd3S-nucleosome complex is now online on Biorxiv: https://t.co/BPvNh6ujDb

We visualize the S. cerevisiae Rpd3S complex bound to a nucleosome including the "evasive" Ume1 subunit!

Congrats, @MarkertJon! Thank you @seyvos for a great collaboration.

[Jon Markert @MarkertJon]

@anthonykkhong @csi_singapore Congrats TK!!

[Ci Ji Lim @cijilim]

Our latest publication reports the cryo-EM structures of the human Polα-Primase DNA elongation complexes - https://t.co/IVPXxLE7ps A Lim lab X Tahirov lab collaboration led by @QixiangHe and Andrey. Thank you, @sarakosman & @NatureSMB, for working with us! Please RT to share! 1/4

[Jon Markert @MarkertJon]

@bmart87 @YSPTSPS @dkjhaunc @maxvcg @fiddle Wow! Is this why you have the blue check mark?? 😆

[Ivan @chaperones4life]

Mechanism of histone H2B monoubiquitination by Bre1 https://t.co/szaUTfEwn5

[Lucas Farnung @LucasFarnung]

Congratulations to Farnung lab PhD Candidate Felix Steinruecke! He has been selected to receive a 2023 NSF Graduate Research Fellowship. Amazing!

[Claudia Mimoso @camimoso]

So excited to share that my thesis work is out now at @MolecularCell! Karen @AdelmanLab and I show that U1 snRNP increases RNA Pol II elongation rate within AT-rich introns, thereby reducing the likelihood of Pol II termination or arrest. Highlights below! https://t.co/HCi5cmVVpX

[cryoEM Papers @cryoEM_Papers]

Binding to nucleosome poises SIRT6 for histone H3 de-acetylation https://t.co/MjdpbEmJNT